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Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

The study findings demonstrate the power of spatial single-cell transcriptomics in studying COVID-19 lung pathology and other health and disease conditions.

1 Mar 2023

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Nanomaterials inspired by amyloid proteins are gaining interest in nanotechnology, due to their modularity, controlled self-assembly and stability.

28 Feb 2023

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

After more than two years since its discovery, six million deaths, and half a billion reported cases, there is still no effective cure for COVID-19. Even though vaccines have lowered the impact of outbreaks, patients that contract the disease can only receive supportive care while they wait for their own body to clear the infection.

24 Feb 2023

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

Researchers reported that some monoclonal nAbs directed against distinct RBD epitopes nested inside the SARS-CoV-2 S could substitute ACE2 as a receptor and support fusion between viral and host cell membranes facilitating viral infectivity.

23 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

New insights into the driving factors of COVID-19 dynamics in England

In a recent study posted to the medRxiv* preprint server, researchers provided quantitative estimates of population-level drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and infection severity by fitting coronavirus disease 2019 (COVID-19) epidemiological surveillance data from England into dynamic transmission models.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Omicron BQ and XBB subvariants most resistant viruses to monoclonal antibodies

A recent study examines the neutralization of SARS-CoV-2 Omicron sub-variants by sera from boosted individuals and those with breakthrough infection.

13 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Smoking tobacco and vaping e-cigarettes may increase healthy young people's risk for severe COVID

New UCLA research suggests that smoking tobacco and vaping electronic cigarettes may increase healthy young people's risk for developing severe COVID illness.

10 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Researchers describe a novel SARS-CoV-2 spike protein component vaccine called MT-001.

9 Feb 2023

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

A study published in the journal PLOS ONE demonstrates the effectiveness of acetic acid, the main component of vinegar, in inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Feb 2023

Researchers discover small molecules that can lock SARS-CoV-2 spike proteins

The infamous spike proteins on the surface of SARS-CoV-2 help it bind to and enter human cells. Because of their important role in spreading infection, these spike proteins are one of the main targets for COVID-19 vaccines and treatments.

9 Feb 2023

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

ACE2 News and Research

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Smoking and vaping may put healthy young people at risk of severe COVID

New insights into the driving factors of COVID-19 dynamics in England

Comparative study on retinoic acid-inducible gene-I of humans and bats

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Omicron BQ and XBB subvariants most resistant viruses to monoclonal antibodies

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Smoking tobacco and vaping e-cigarettes may increase healthy young people's risk for severe COVID

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

Researchers discover small molecules that can lock SARS-CoV-2 spike proteins

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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