Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Subjective cognitive decline predicts future dementia risk, study finds

A study in JAMA Psychiatry finds that subjective cognitive decline (SCD) significantly predicts the risk of mild cognitive impairment (MCI), Alzheimer's disease (AD), and all-cause dementia in older adults.

7 Jul 2024

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

An international panel of experts led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, under the umbrella of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment, has produced a consensus statement on sex and gender disparities in resilience to Alzheimer's disease and call for incorporating these differences in future research.

5 Jul 2024

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

The impact of heparan-sulfate-modified proteoglycans (HSPGs) on Alzheimer's disease-associated pathways.

5 Jul 2024

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed.

3 Jul 2024

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

3 Jul 2024

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

3 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

Study finds promising new target for the treatment of Alzheimer's disease

A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State.

2 Jul 2024

No organ is an island: Genetic study shows unique but interconnected aging markers

Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.

2 Jul 2024

Youth and midlife diet quality linked to better brain health in later years

Eating a high-quality diet in youth and middle age could help keep your brain functioning well in your senior years, according to new preliminary findings from a study that used data collected from over 3,000 people followed for nearly seven decades.

1 Jul 2024

Serotonin 2C receptor in the brain regulates memory in people and animal models, research shows

Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and animal models.

28 Jun 2024

New method developed to map mechanistic connections between diseases

Tampere University researchers developed a method to map mechanistic connections between diseases, revealing deeper associations beyond traditional classifications based on affected organs and symptoms.

28 Jun 2024

Penn researchers aim to uncover the underlying biological mechanisms of TBI-related neurodegeneration

A team of researchers led by Penn Medicine will investigate the link between traumatic brain injuries (TBI) and Alzheimer's disease and related dementias (ADRD) over the next five years with a $10 million grant from the National Institute of Neurological Disorders and Stroke (NINDS).

28 Jun 2024

Study reveals brain health benefits of intermittent fasting and healthy diet plans

Researchers from Johns Hopkins Medicine and the National Institutes of Health's National Institute on Aging say their study of 40 older adults with obesity and insulin resistance who were randomly assigned to either an intermittent fasting diet or a standard healthy diet approved by the U.S. Department of Agriculture (USDA) offers important clues about the potential benefits of both eating plans on brain health.

25 Jun 2024

Automated prediction of Alzheimer's disease progression using speech and machine learning

Trying to figure out whether someone has Alzheimer's disease usually involves a battery of assessments-;interviews, brain imaging, blood and cerebrospinal fluid tests.

25 Jun 2024

New study in rhesus macaques offers early intervention window for Alzheimer's

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer's and similar diseases, before extensive brain cell death and dementia set in.

24 Jun 2024

Novel algorithm predicts on-road driving ability in older adults with cognitive concerns

As the world's population ages, so does the proportion of older drivers on the road. Safe driving requires adequate memory, perceptual and motor skills, and executive function abilities.

24 Jun 2024

Research finds causal evidence tying cerebral small-vessel disease to Alzheimer’s, dementia

Research led by in part by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) finds that the most common cerebral small-vessel disease feature seen in brain magnetic resonance imaging is a primary vascular factor associated with dementia risk.

21 Jun 2024

UCF researcher further explores nanotech to improve cancer and disease detection

Early discovery of debilitating diseases such as cancer or dementia is critical in determining treatment and saving lives.

21 Jun 2024

WEHI spinout aims to revolutionize the development of cancer drugs

Australia has cemented its role in becoming a major player in the next generation of medicines with the launch of Ternarx – a globally competitive biotechnology company dedicated to finding new treatments for hard-to-treat cancers.

20 Jun 2024

Alzheimer's Disease News and Research

Further Reading

Subjective cognitive decline predicts future dementia risk, study finds

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

White blood cell type identified as important contributor to inflammation in obesity

Study finds promising new target for the treatment of Alzheimer's disease

No organ is an island: Genetic study shows unique but interconnected aging markers

Youth and midlife diet quality linked to better brain health in later years

Serotonin 2C receptor in the brain regulates memory in people and animal models, research shows

New method developed to map mechanistic connections between diseases

Penn researchers aim to uncover the underlying biological mechanisms of TBI-related neurodegeneration

Study reveals brain health benefits of intermittent fasting and healthy diet plans

Automated prediction of Alzheimer's disease progression using speech and machine learning

New study in rhesus macaques offers early intervention window for Alzheimer's

Novel algorithm predicts on-road driving ability in older adults with cognitive concerns

Research finds causal evidence tying cerebral small-vessel disease to Alzheimer’s, dementia

UCF researcher further explores nanotech to improve cancer and disease detection

WEHI spinout aims to revolutionize the development of cancer drugs

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