Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Geron plans to advance clinical program for spinal cord injury

Geron Corporation today announced the company’s plan to advance clinical development of its human embryonic stem cell (hESC)-based product, GRNOPC1, for the treatment of spinal cord injury.

31 Oct 2009

Bayer HealthCare's Phase II study results of imaging agent florbetaben

Bayer HealthCare presented results from a global Phase II study of florbetaben, its imaging agent in development for the detection of cerebral beta-Amyloid plaques, at the 19th World Congress of Neurology (WCN).

30 Oct 2009

Eisai reports global Phase III study results of eribulin mesylate

Eisai Inc. today announced preliminary results from a recently completed Phase III study with eribulin mesylate (E7389), discovered and developed by the company, in patients with locally advanced or metastatic breast cancer.

30 Oct 2009

Isotechnika Pharma develops portfolio of NICAMs with potent cyclophilin inhibition

Isotechnika Pharma Inc. today announced that it has developed a portfolio of non-immunosuppressive cyclosporine analogue molecules (NICAMs) with potent cyclophilin inhibition. Cyclophilin inhibition has garnered considerable attention as a novel therapy in the treatment of a wide range of diseases including hepatitis C, stroke, and chronic neurological disorders such as Parkinson's, Lou Gehrig's, and Alzheimer's.

30 Oct 2009

Clinical data on the validation set 'Alzheimer patients versus healthy controls' for AclarusDx presented

ExonHit Therapeutics yesterday presented clinical data on the validation set “Alzheimer patients versus healthy controls” for AclarusDx™ (formerly EHT Dx21), its blood-based diagnostic test for the detection of Alzheimer’s disease (AD), at the 2nd Conference of Clinical Trials on Alzheimer’s Disease (CTAD) in Las Vegas, USA.

30 Oct 2009

New state-of-the-art biotechnology center opened on the West Coast

As part of its strategy to discover and develop more biotechnology medicines, Eli Lilly and Company today officially opened a new state-of-the-art biotechnology center on the West Coast.

30 Oct 2009

Dr. Heather Greene to receive 2009 C.A.R.E. Pharmacy Award

Eisai Inc. and the Alzheimer's Association announce today that Heather Greene, PharmD is the recipient of the 2009 C.A.R.E. Pharmacy Award.

30 Oct 2009

NIH launches randomized trail to determine whether lower BP goal cuts the risk of heart and kidney diseases

The National Institutes of Health is launching a large multicenter randomized clinical trial to determine whether maintaining blood pressure levels lower than current recommendations further reduces the risk of cardiovascular and kidney diseases, or age-related cognitive decline.

30 Oct 2009

New reports detail hits taken by Medicaid programs in state budget cuts

State Medicaid and other health programs have fallen under the axe or been moved onto the chopping block this week.

29 Oct 2009

Amorfix Life Sciences achieves 100% specificity in using EP-vCJD Blood Screening Assay

Amorfix Life Sciences, a company focused on treatments and diagnostics for misfolded protein diseases, today announced it has achieved 100% specificity (no reproducible false positive results) upon testing 19,000 blood donations for variant Creutzfeldt-Jakob Disease ("vCJD") with the EP-vCJD(TM) Blood Screening Assay at l'Etablissement Français du Sang de Pyrénées Méditerrannée ("EFS-PM") in Montpellier, France.

29 Oct 2009

Third-quarter 2009 financial results of Antigenics announced

Antigenics Inc. reported today its results for the quarter ended September 30, 2009. The company incurred a net loss attributable to common stockholders of $10.8 million, or $0.13 per share, basic and diluted, for the third quarter of 2009, compared with a net loss attributable to common stockholders in the third quarter of 2008 of $11.4 million, or $0.17 per share, basic and diluted.

29 Oct 2009

Effects of head injuries on players in the NFL: House Judiciary Committee's call to experts

The House Judiciary Committee today called upon national experts and stakeholders in the fields of science and sport to better understand the effects of head injuries on players in the National Football League (NFL). Nationally recognized sports physician and neurosurgeon, Julian E. Bailes, M.D. was called to provide expert testimony based on decades of research detailing how repetitive head trauma on the field leads to long-term neurological damage among athletes.

29 Oct 2009

Long-term effects of statin therapy could lead to transient or permanent cognitive impairment

Besides their tremendous value in treating high cholesterol and lowering the risk of heart disease, statins have also been reported to potentially lower the risks of other diseases, such as dementia. However, a study in the October Journal of Lipid Research finds that similar statin drugs can have profoundly different effects on brain cells -both beneficial and detrimental.

29 Oct 2009

CTE cases are misdiagnosed as Alzheimer's disease, says CSTE researchers

The Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) announced today that a recently deceased member of the NFL Hall of Fame suffered from the degenerative brain disease Chronic Traumatic Encephalopathy (CTE) when he died, becoming the 10th former NFL player diagnosed with the disease.

29 Oct 2009

No scientific proof that patients with Alzheimer's disease benefit from drugs containing the agent memantine

There is no scientific proof that patients with moderate or severe Alzheimer's disease benefit from drugs containing the agent memantine. This is the conclusion in the final report that the Institute for Quality and Efficiency in Health Care (IQWiG) published in September 2009.

29 Oct 2009

NCKU transfers microalgal docosahexaenoic acid production technology to Vedan Biotechnology

NCKU President, Academician Michael Ming-Chiao Lai, signed Technology Transfer Agreement in this morning with Mr. Tou-Hsiung Yang, Chairman of Vedan International (Holding) Ltd, witnessed by Vedan Biotechnology President Shih-An (Raymond) Yang and the inventor, Prof. Huey-Lang Yang of the NCKU Institute of Biotechnology.

28 Oct 2009

The Endocrine Society urges NIH to increase funding for stem cell research

Stem cell research holds great promise for the treatment of millions of Americans with debilitating and possibly fatal diseases. Current legislation and guidelines, however, continue to limit researchers' endeavors in unlocking the potential breakthroughs that stem cell research can provide. To address this concern, today The Endocrine Society issued a Position Statement (http://www.endo-society.org/advocacy/policy) calling for an increase in NIH funding for stem cell research as well as expanding the scope of funding to include promising yet neglected areas of stem cell research.

28 Oct 2009

Alzheimer's Disease News and Research

Further Reading

Geron plans to advance clinical program for spinal cord injury

Bayer HealthCare's Phase II study results of imaging agent florbetaben

Eisai reports global Phase III study results of eribulin mesylate

Isotechnika Pharma develops portfolio of NICAMs with potent cyclophilin inhibition

Clinical data on the validation set 'Alzheimer patients versus healthy controls' for AclarusDx presented

New state-of-the-art biotechnology center opened on the West Coast

Dr. Heather Greene to receive 2009 C.A.R.E. Pharmacy Award

NIH launches randomized trail to determine whether lower BP goal cuts the risk of heart and kidney diseases

New reports detail hits taken by Medicaid programs in state budget cuts

Amorfix Life Sciences achieves 100% specificity in using EP-vCJD Blood Screening Assay

Third-quarter 2009 financial results of Antigenics announced

Effects of head injuries on players in the NFL: House Judiciary Committee's call to experts

Long-term effects of statin therapy could lead to transient or permanent cognitive impairment

CTE cases are misdiagnosed as Alzheimer's disease, says CSTE researchers

No scientific proof that patients with Alzheimer's disease benefit from drugs containing the agent memantine

NCKU transfers microalgal docosahexaenoic acid production technology to Vedan Biotechnology

The Endocrine Society urges NIH to increase funding for stem cell research

Amorfix Life Sciences detects prions in blood from non-human primates that were orally-infected with BSE

Astellas enters into agreement with Medivation to develop MDV3100

Discovery of molecular pathway in brain may reverse cognitive impact of sleep deprivation

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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