Anticonvulsant News and Research

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Older-style antidepressants, as well as anticonvulsant drugs, can help ease the disabling pain caused by nerve tissue damage

For many years antidepressants, which are believed to work by dampening pain signals, have been the first-line drugs for neuropathic pain. "It is usual to start with an antidepressant like amitriptyline, and if this fails then try an anticonvulsant," says Phil Wiffen, a researcher at Churchill Hospital in Oxford, England. "The results of these meta-analyses suggest this is probably still the best approach to take."

19 Jul 2005

Anticonvulsant drug valproate poses greater birth-defect risk than suspected

Use of the anticonvulsant drug valproate during pregnancy may pose a significantly great risk of birth defects than does use of other antiseizure medications.

22 Mar 2005

Atkins diet may be beneficial for people with epilepsy

Imagine that your child with epilepsy could have seizures less frequently, by eating more protein and less carbs. The first comprehensive review of possible dietary treatments of epilepsy has recently been published.

31 Jan 2005

Anti-seizure drugs slow aging in roundworms

Researchers at Washington University School of Medicine in St. Louis have discovered that a class of anti-seizure medications slows the rate of aging in roundworms. The worms, when exposed to drugs used to treat epilepsy in humans, lived longer and retained youthful functions longer than normal.

17 Jan 2005

A novel gene therapy strategy may help reduce seizures in adults suffering from epilepsy

Deborah Lin, from the Faculty of Medical and Health Sciences, is investigating the effects of a therapeutic gene transfer in a particular form of epilepsy which affects the brain’s temporal lobe region.

12 Oct 2004

U.S. Supreme Court to decide whether anti-drug laws should apply to the medicinal use of marijuana

The U.S. Supreme Court is to decide whether anti-drug laws should apply to the medicinal use of marijuana.

29 Jun 2004

Cyberonics announces two new Phase IV epilepsy studies

Cyberonics, Inc. has announced that study sites are being recruited for two new Phase IV epilepsy studies and that three epilepsy educational symposia have been scheduled.

16 Jun 2004

A new guideline evaluates the treatment of infantile spasms

A new guideline developed by the American Academy of Neurology and the Child Neurology Society evaluates the treatment of infantile spasms. The guideline is published in the May 25 issue of Neurology, the scientific journal of the American Academy of Neurology.

24 May 2004

Antiepileptic drug Levetiracetam may help patients with Parkinson's disease

In patients with Parkinson's disease, the antiepileptic drug levetiracetam (Keppra(R)) reduced the involuntary movements (dyskinesia) associated with levodopa, the medication most commonly used to treat Parkinson's disease, according to a study presented today at the 56th annual meeting of the American Academy of Neurology.

29 Apr 2004

Gene of immune system linked to severe adverse drug reaction called Stevens-Johnson syndrome (SJS)

In a study of Han Chinese patients, researchers have for the first time directly linked a gene of the immune system to a severe adverse drug reaction called Stevens-Johnson syndrome (SJS), according to a Duke University Medical Center medical geneticist and collaborators in Taiwan.

1 Apr 2004

FDA has approved Zyprexa, injectable anti-psychotic drug

Physicians have a new fast-acting option for controlling the potentially crippling effects of acute agitation in patients suffering with schizophrenia and bipolar mania. The U.S. Food and Drug Administration (FDA) has approved Zyprexa® IntraMuscular (olanzapine for injection), an injectable form of Lilly's top-selling medication.

30 Mar 2004