Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Antidepressants will cheer you up and stop a repeat heart attack

According to the National Institute of Mental Health, depression and heart disease have long been associated, and one can often lead to the other.

6 Jul 2005

Increase in heart surgery mortality from SSRIs or depression?

Duke University Medical Center researchers have found that patients who were using a class of anti-depression drugs known as selective serotonin reuptake inhibitors (SSRI) prior to undergoing coronary artery bypass surgery have significantly higher death and rehospitalization rates up to five years after the procedure than patients who were not on SSRIs.

26 May 2005

Investigational device-based therapies will lead to entirely new treatment options for chronic depression sufferers

Researchers said that developing brain stimulation techniques such as transcranial magnetic stimulation (TMS), vagal nerve stimulation and deep brain stimulation are emerging as significant treatment options for the millions of patients "poorly served" by existing therapies.

23 May 2005

Use of a common type of antidepressant may increase gastrointestinal (GI) bleeding

In fact, the study suggests that the increase is similar to that associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs, known as pain relievers). DDW is the largest international gathering of physicians, academics and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

17 May 2005

St. John's Wort only minimally effective in relieving major depression

St. John’s Wort, the herbal medicinal long thought to relieve symptoms of depression, provides only minor benefits in patients with the most acute depression and perhaps no benefit for those with chronic depression.

16 May 2005

Magnetic stimulation treatment for depression

Barbara Baas ran away from home and tried to kill herself as a teenager. As an adult, she has tried more than 15 varieties of antidepressants. But, thanks to a new weapon, she has finally reached a truce in a 45-year battle.

10 May 2005

"Anxiety Gene" linked to depression, makes the body out of tune

U.S. scientists in viewing the human body as a well-tuned orchestra, say that think they may have found a discordant note in the form of a gene which appears to increase the likelihood of some people developing anxiety and depression.

9 May 2005

Does clinical depression bring about chronic pain? Or does pain lead to depression?

Does clinical depression bring about chronic pain? Or does pain lead to depression? Because these two conditions frequently co-exist--30 to 54 percent of patients with major depressive disorder also suffer persistent physical pain--there has been much speculation about whether one causes the other or whether a common underlying factor provokes both. Results of studies into the precise nature of this relationship, however, have been inconsistent.

5 May 2005

Psychological treatment most effective treatment for pediatric obsessive-compulsive disorder

Psychological treatment that teaches children to face their fears is the most effective treatment for pediatric obsessive-compulsive disorder (OCD), according to a new Mayo Clinic analysis of previously published research.

4 May 2005

Alarms better than medication for stopping bedwetting

Alarms that buzz, ring or light up when a child wets the bed are more effective at stopping bedwetting than medications like the drug commonly used to prevent urination, according to a new review of recent studies.

2 May 2005

Antidepressant medication or psychotherapy may be effective in treating chronically depressed patients when the other is not

Switching from an antidepressant medication to psychotherapy or vice versa may improve symptoms in chronically depressed patients who prove unresponsive to their initial treatment, according to an article in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 May 2005

Actor-patients' requests for medications boost prescribing for depression

Researchers funded by the National Institute of Mental Health (NIMH), have found that requests from patients for medications have a "profound effect" on physicians prescribing for major depression and adjustment disorder. These findings indicate that direct-to-consumer (DTC) marketing of prescription medications for depression may exert significant influence on treatment decisions.

27 Apr 2005

The power of advertising means you may get medications you don't need

A study published this month confirms what has often been suspected, that prescription drug advertising not only persuades patients to ask for certain medications but also has a profound influence on what doctors prescribe.

26 Apr 2005

Direct-to-consumer advertising may influence physicians' prescribing decisions

Patients requesting specific medications can have a profound effect on physicians prescribing medications for major depression, according to a new study in the April 27 issue of JAMA.

26 Apr 2005

Study may lead to a better understanding of how antidepressants like Prozac work

According to results published in today's issue of the journal Neuron, a study in mice proposes that dopamine and serotonin neurotransmitter systems in the brain occasionally get their signals crossed, causing delays in stabilizing mood.

7 Apr 2005

SSRI antidepressants "hijack" dopamine signaling as well launching serotonin signals

Researchers have discovered that antidepressant drugs such as Prozac not only affect levels of the neurotransmitter serotonin in the brain, but also "hijack" dopamine signaling as well--causing it to launch serotonin signals. Their findings offer new insight into how Prozac and other "selective serotonin uptake inhibitors" (SSRIs) work and how they might cause problems in patients taking them.

6 Apr 2005

Cognitive therapy to treat moderate to severe depression works just as well as antidepressants

The study, conducted by researchers at the University of Pennsylvania and Vanderbilt University, challenges the American Psychiatric Association guidelines that antidepressant medications are the only effective treatment for moderately to severely depressed patients.

5 Apr 2005

Light therapy effectively treats mood disorders

A study commissioned by the American Psychiatric Association and led by a psychiatrist at the University of North Carolina at Chapel Hill School of Medicine has found that light therapy effectively treats mood disorders, including seasonal affective disorder (SAD) and other depressive disorders.

4 Apr 2005

Cognitive therapy may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression

Cognitive therapy, when provided by an experienced therapist, may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression, according to an article in the April issue of Archives of General Psychiatry.