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The burgeoning Indian AIDS epidemic

India, home to one-sixth of the human race, has an AIDS epidemic. Five million Indians are living with HIV infection. The stakes are high; the government is racing against time.

21 Dec 2004

Imatinib mesylate (Gleevec) inhibits important pathways that spur cancer growth

A new clinical study has shown that imatinib mesylate (Gleevec) has activity in AIDS-related Kaposi's sarcoma (KS). Imatinib inhibits important pathways that spur cancer growth, resulting in the regression of KS tumors within 4 weeks in some patients. The study will be published November 30 in the Journal of Clinical Oncology (JCO).

30 Nov 2004

Viral Genetics announces effects of VGV-1 in antiretroviral non-responding HIV infections

Viral Genetics announced today that the results of a clinical trial of its investigational therapy for HIV infection, VGV-1, were recently published in a peer reviewed journal, HIV & AIDS Review.

29 Nov 2004

One in five women with HIV in the United States has no health insurance

One in five women with HIV in the United States has no health insurance. Half of the estimated 460,000 women and men who need lifesaving antiretroviral drugs are not getting them, according to a recent report by the Institute of Medicine (IOM) of the National Academy of Sciences.

29 Nov 2004

Guatemalan Congress repeals law that restricted access to medicines

The Guatemalan Congress's repeal of a law that severely restricts people's access to affordable essential medicines is a positive step forward.

29 Nov 2004

Moldova making progress in fight against HIV/AIDS and tuberculosis

Moldova’s early actions to fight HIV/AIDS and tuberculosis are slowing the rise of the country’s dual tuberculosis and AIDS epidemics, the World Bank reports.

29 Nov 2004

Women now making up nearly half of the 37.2 million adults (aged 15-49) living with HIV worldwide

A new report released today shows that the number of women living with HIV has risen in each region of the world over the past two years, with the steepest increases in East Asia, followed by Eastern Europe and Central Asia. In East Asia, there was a 56% increase over the past two years, followed by Eastern Europe and Central Asia with 48%.

23 Nov 2004

Low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries

Results of a randomised trial in this week’s issue of THE LANCET highlight how the low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries to help reduce illness and death from opportunistic infections such as pneumonia.

18 Nov 2004

Silicone facial implants provide HAART patients with a healthier appearance

Highly active antiretroviral therapy (HAART) for the treatment of HIV/AIDS is the name given to treatment regimens recommended by leading HIV experts to aggressively suppress viral replication and progress of HIV disease. These treatment regimens have been shown to reduce the amount of virus so that it becomes undetectable in a patient's blood.

16 Nov 2004

HIV drugs known as protease inhibitors also protect against Malaria

Scientists from The Queensland Institute of Medical Research (QIMR) have found that a group of HIV drugs known as protease inhibitors may also be effective for treating or preventing malaria.

11 Nov 2004

Protease inhibitors used to treat HIV-1 infection may also be effective for treatment or prevention of malaria

The study found protease inhibitors inhibited the growth of P. falciparum, the malaria parasite that causes most disease. These findings may also expose a previously unexplored vulnerability in the parasite that could lead to a new class of anti-malarial drug.

8 Nov 2004

New molecular tool to pinpoint DNA mutations among thousands of cells

Scientists have designed a new molecular tool, dubbed "LigAmp," to pinpoint DNA mutations among thousands of cells, the equivalent of searching for a single typo in an entire library of books.

28 Oct 2004

Researchers investigate new treatment options, including ways to boost immune responses to better control HIV

Highly active antiretroviral therapy (HAART) for the treatment of individuals infected by HIV-1 is limited by high costs, drug resistance, and drug-related toxicities. This has led researchers to investigate new treatment options, including ways to boost immune responses to better control HIV.

25 Oct 2004

Boehringer Ingelheim - New Drug Application (NDA) for tipranavir

The Company is seeking accelerated approval of tipranavir and has requested a priority, six-month review of the NDA. Priority review designation is based upon whether a drug provides a significant improvement in the treatment of a serious or life-threatening disease.

25 Oct 2004

FDA grants traditional approval for Fuzeon (enfuvirtide), to treat HIV

Roche and Trimeris today announced that the U.S. Food and Drug Administration (FDA) has granted traditional approval to Fuzeon (enfuvirtide), the first and only fusion inhibitor for the treatment of HIV.

18 Oct 2004

PAHO reports on the care and treatment of people with HIV in the Americas

The Pan American Health Organization (PAHO) has issued reports on the first seven of 47 countries and territories with new and specific data on the care and treatment of people with HIV in the Americas.

13 Oct 2004

One group of drugs that is effective in fighting HIV may also be promoting the death of sensory nerves in the skin

One group of drugs that is effective in fighting HIV may, paradoxically, also be promoting the death of sensory nerves in the skin, according to a study presented October 5, 2004, at the 129th annual meeting of the American Neurological Association in Toronto.

5 Oct 2004

Antiretroviral treatment may provide protection against HIV transmission during breast-feeding

Women who take combination AIDS drugs not only have benefits for their own health but also may pass along high levels of the medication through breast-feeding, potentially protecting their infants from HIV infection

30 Sep 2004

PAHO outlines health challenges ahead

Pan American Health Organization (PAHO) Director Dr. Mirta Roses today presented a report summarizing PAHO's work over the past year in the Americas, during a special session of a meeting of the region's ministers of health taking place at PAHO headquarters this week.

28 Sep 2004

Discovery of dopamine terminal injury in brains of people with HIV dementia

Scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have discovered a key mechanism in the brains of people with human immunodeficiency virus (HIV) dementia.

20 Sep 2004