Antiretroviral News and Research

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Are men or women impacted more by adverse reactions to prescription drug treatments?

Recently, researchers presented an overview of sex-based differences in adverse drug reactions (ADRs) based on epidemiology, technique, and underlying mechanism data.

11 Oct 2022

Did telehealth appointments improve HIV care retention during the COVID-19 pandemic?

In a new study, researchers assessed how measures of retention in human immunodeficiency virus (HIV) care have changed due to the COVID-19 pandemic.

6 Oct 2022

How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

The kinetics of T cell response, the inflammatory profile, and the pox-specific T cell induction in monkeypox infection

A new study describes the changes in immune T cell profile over time following monkeypox infection.

14 Sep 2022

CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

Researchers investigated the prevalence of HIV, and other recent sexually transmitted infection diagnoses among persons with monkeypox.

12 Sep 2022

Cellulitis, a deep bacterial infection of the skin, as a monkeypox complication

Researchers described two cases of human monkeypox and deep skin infection.

5 Sep 2022

Dolutegravir-based regimen more effective for treating pregnant people with HIV-1

Dolutegravir-based antiretroviral therapies (ART) for HIV-1 are more effective for pregnant people than some other ART regimens commonly used in the U.S. and Europe, according to a study led by Harvard T.H. Chan School of Public Health researchers.

1 Sep 2022

SARS-CoV-2 mRNA vaccination reveals HIV hiding in immune cells

Vaccination with a SARS-CoV-2 mRNA vaccine revealed HIV hiding in immune cells in blood from people with HIV, according to lab research led by Weill Cornell Medicine investigators.

19 Aug 2022

Study detects asymptomatic monkeypox virus infection

A new study published in the Annals of Internal Medicine aimed to assess the presence of MPVX in the anorectal samples of MSM who had undergone routine tests for sexually transmitted infections from 5th June to 11th July 2022.

17 Aug 2022

Report documents the detection of monkeypox virus in anal samples taken from asymptomatic MSM

A brief research report documents positive monkeypox virus PCR results found in anal samples taken from asymptomatic MSM (men who have sex with men).

16 Aug 2022

Case series of first 3 monkeypox patients in Massachusetts treated with tecoviromat

A team of US-based scientists has described the therapeutic efficacy of a pan-Orthopoxvirus inhibitor, tecovirimat, in patients with monkeypox infection

3 Aug 2022

Symptoms of monkeypox differ from previous outbreaks

A new study describes the clinical characteristics of monkeypox infections during the current outbreak.

1 Aug 2022

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

Finding a cure for HIV has been extremely difficult, in part because the virus hides from antiretroviral treatments in one of the hardest places to reach: the brain.

27 Jul 2022

Innovative technology reveals new insights into cellular reservoirs of HIV

In a presentation today at AIDS 2022, the 24th International AIDS Conference in Montreal, scientists with the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC) and their collaborators described how their use of cutting-edge technology revealed new insights into cellular reservoirs of HIV and what those observations could mean for the next steps in HIV cure research. NIAID is part of the National Institutes of Health.

27 Jul 2022

Combinations of broadly neutralizing antibodies may be a more effective approach to treat HIV

Carefully designed cocktails of broadly neutralizing antibodies (bNAbs) could help treat HIV while minimizing the risk of the virus escaping treatment, suggests a study published today in eLife.

20 Jul 2022

Best available chemotherapy for HIV-related Kaposi sarcoma would save lives and be cost-effective in Africa

Although antiretroviral therapy has markedly improved survival in people with AIDS-associated Kaposi sarcoma (a type of cancer caused by a virus), the condition is still a life-threatening problem in low- and middle-income countries.

15 Jul 2022

Researchers receive $3.25 million NIH grant to better understand the oral manifestations of HIV

Researchers at the Case Western Reserve University School of Dental Medicine will use a $3.25 million grant from the National Institutes of Health (NIH) to better understand how HIV impacts the human body, from mouth lesions to oral cancer.

11 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

HIV accelerates epigenetic aging soon after initial HIV infection

HIV has an "early and substantial" impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to a study by UCLA researchers and colleagues.

1 Jul 2022

Crystal structure of a human endogenous reverse transcriptase revealed

The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according to a study co-authored by a Rutgers researcher.

30 Jun 2022