Antiretroviral News and Research

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Analysis shows dramatic fall in the number of people living with undiagnosed HIV in England

England is on track to have diagnosed 95% of people living with HIV by 2025, putting it in a strong position to eliminate HIV transmission by 2030, say researchers at the MRC Biostatistics Unit, University of Cambridge, and Public Health England (PHE).

24 Sep 2021

Novel combination therapy may prolong viral suppression in patients with HIV

A novel combination treatment may increase the ability of monoclonal antibodies to control viral infection in patients diagnosed with HIV, according to a Northwestern Medicine study published in Science Translational Medicine.

9 Sep 2021

People living with HIV have higher risk of sudden cardiac death, finds study

People living with human immunodeficiency virus (HIV) have a higher risk of sudden cardiac death than people who do not have HIV, especially if the virus is not well-controlled or if they have other heart disease risk factors.

8 Sep 2021

Investigational vaccine does not provide sufficient protection against HIV infection

An investigational HIV vaccine tested in the "Imbokodo" clinical trial conducted in sub-Saharan Africa posed no safety concerns but did not provide sufficient protection against HIV infection, according to a primary analysis of the study data. The Phase 2b proof-of-concept study, which began in November 2017, enrolled 2,637 women ages 18 to 35 years from five countries.

31 Aug 2021

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

Researchers at Albert Einstein College of Medicine and the City University of New York Graduate School of Public Health and Health Policy have been awarded a five-year, $14.5 million grant from the National Institutes of Health to continue leading and expand their research on HIV treatment and care in five Central African nations.

24 Aug 2021

COVID booster shots might be needed in subgroup of HIV-positive individuals

The coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a global pandemic destroying lives and economies. COVID-19 is not curable, so vaccines are the only safeguard during this pandemic.

23 Aug 2021

CUNY SPH and NYC Health Department receive grant to study long-acting injectables for HIV

The National Institute of Mental Health has awarded the CUNY Graduate School of Public Health and Health Policy and the New York City Department of Health and Mental Hygiene a thirty month grant to support long-acting injectable antiretroviral therapy access, uptake, and adherence among people with HIV enrolled in the Ryan White HIV/AIDS Program (hereafter "Ryan White").

23 Aug 2021

CUNY SPH and NYC Health Department receive $3.3 million grant to test new HIV intervention

The National Institute of Mental Health has awarded the CUNY Graduate School of Public Health and Health Policy and the New York City Department of Health and Mental Hygiene a five-year, $3.3 million grant to test a new strategy to help people living with HIV achieve viral suppression.

18 Aug 2021

Researchers receive $26.5 million NIH grant to pursue a new strategy for curing HIV

Over the last 40 years, HIV has shifted from a deadly and mysterious virus to one that can be controlled with daily drugs. But attempts to completely eliminate the virus from the bodies of people living with HIV, curing them for good, have failed.

17 Aug 2021

Risk factors for hospitalization among HIV patients infected with SARS-CoV-2

The hospitalization of PWH with COVID-19 is related to host factors such as older age and co-morbidities, rather than due to traditional metrics of HIV.

11 Aug 2021

COVID-19 vaccine likely protects people living with HIV, study shows

A Johns Hopkins Medicine research team has shown that people living with the human immunodeficiency virus (HIV) are likely to be protected against SARS-CoV-2, the virus that causes COVID-19, if they are fully vaccinated.

11 Aug 2021

Report highlights global shortfalls to end HIV infections among children and young women

In the final report from the Start Free, Stay Free, AIDS Free initiative, UNAIDS and partners warn that progress towards ending AIDS among children, adolescents and young women has stalled and none of the targets for 2020 were met.

23 Jul 2021

Experts develop consensus statement to help improve long-term well-being of people with HIV

Since antiretroviral therapy (ART) for HIV was introduced in 1996, AIDS-related morbidity and mortality has declined significantly.

21 Jul 2021

Study: Adolescent girls and young women can and will use HIV prevention products with consistency

Adolescent girls and young women can and will use HIV prevention products with consistency, according to interim results of a study of two different methods: daily use of the antiretroviral (ARV) tablet Truvada as oral pre-exposure prophylaxis (PrEP) and the monthly dapivirine vaginal ring, a new HIV prevention product currently under regulatory review in several countries.

15 Jul 2021

New biomarkers can predict HIV remission after antiretroviral therapy interruption

New biomarkers that predict HIV remission after antiretroviral therapy (ART) interruption are critical for the development of new therapeutic strategies that can achieve infection control without ART, a condition defined as functional cure.

29 Jun 2021

People living with HIV/AIDS more likely to have suicidal thoughts and die from suicide

A new study by researchers at Penn State College of Medicine indicates that people living with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) - approximately 38 million worldwide - are more likely to have suicidal thoughts and die from suicide than members of the general population.

28 Jun 2021

Special type of stem cell can reduce the amount of HIV virus

In a groundbreaking study, a team of UC Davis researchers has discovered a special type of stem cell that can reduce the amount of the virus causing AIDS, boosting the body's antiviral immunity and repairing and restoring the gut's lymphoid follicles damaged by the simian immunodeficiency virus (SIV), the equivalent of the human immunodeficiency virus (HIV) in non-human primates.

24 Jun 2021

Internal communication network in mammals provides new insights on obesity, skin disorders

National Institutes of Health scientists and their collaborators have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as obesity and inflammatory skin disorders develop. The new research is published in Cell.

24 Jun 2021

Deep learning could transform the ability to accurately interpret HIV test results

Pioneering technology developed by UCL and Africa Health Research Institute researchers could transform the ability to accurately interpret HIV test results, particularly in low- and middle-income countries.

18 Jun 2021

ACTG launches phase 1 HIV cure study evaluating two promising therapies

The AIDS Clinical Trials Group, the largest global HIV research network, today announced the launch of A5386, a phase 1 HIV cure study evaluating two promising therapies.

10 Jun 2021