Autoantibodies News and Research

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Genetic signature helps distinguish latent autoimmune diabetes in adults from pediatric-onset T1D

A multi-center team of researchers led by Children's Hospital of Philadelphia has discovered a genetic signature that could help distinguish an adult-onset form of diabetes sharing many type 1 diabetes characteristics from pediatric-onset T1D, opening the door to potentially more straightforward diagnostic tests for the adult condition and improving responses by ensuring patients receive the most appropriate treatment.

7 Jan 2020

Researchers reveal how antibodies assemble to form a circle for defensive attack

Antibodies are key players in our immune system. These antibodies recognize antigens displayed on foreign cell membranes and thereby recruit attacking forces, called complements.

6 Jan 2020

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

An autoimmune attack on uninfected red blood cells likely contributes to anaemia - a shortage of red blood cells - in people with malaria, according to a new study published in eLife.

12 Nov 2019

UM launches CAR-T clinical trial for patients with myasthenia gravis

Neuromuscular experts with the University of Miami Health System and the Miller School of Medicine will launch a Phase 1/2 clinical trial (NCT04146051) using the CAR-T drug, Descartes-08, to treat patients with generalized myasthenia gravis.

5 Nov 2019

Breast cancer could soon be detected early using a blood test

Researchers have found that breast cancer may be successfully detected up to five years before any symptoms appear using a blood test. The results of this land mark study which could mean diagnosis of breast cancer early and treating it more effectively, were presented at the 2019 NCRI Cancer Conference Sunday (3rd November 2019).

4 Nov 2019

Antibody-based eye drops show promise in treating dry eye disease

Dry eye is a condition wherein a person doesn’t have enough tears to lubricate the eye. With the chronic lack of sufficient lubrication, moisture, and nourishment on the eye, it can lead to eye irritation, inflammation, and eventually, scarring.

14 Oct 2019

Rotavirus plays role in development of type 1 diabetes

A new article published in the journal PLOS Pathogens on October 10, 2019, claims that the common rotavirus may be responsible for the occurrence of type 1 diabetes, a form of diabetes which occurs in children and is due to destruction of the pancreatic islet cells that produce the hormone insulin to normalize blood glucose levels.

13 Oct 2019

Antibody-based eye drop treatment reduces signs and symptoms of dry eye disease

Researchers at the University of Illinois at Chicago are the first to identify the presence of a specific type of antibody, called anti-citrullinated protein autoantibodies, or ACPAs, in human tear fluid.

11 Oct 2019

Rotavirus infection may play a role in type 1 diabetes development

Rotavirus infection may play a role in the development of type 1 diabetes, according to a front matter article published October 10 in the open-access journal PLOS Pathogens by Leonard C. Harrison of the University of Melbourne in Australia, and colleagues.

From PLOS ONE 10 Oct 2019

UAB researchers find key role for IgG autoantibodies in IgA nephropathy

The most common form of the kidney disease called glomerulonephritis is IgA nephropathy.

24 Sep 2019

Dogs can suffer from same autoimmune encephalitis as humans, research reveals

Researchers from North Carolina State University have found that dogs can suffer from the same type of autoimmune encephalitis that people do. The finding could lead to better screening methods for diagnosis and possibly more effective treatments for canine encephalitis.

24 Sep 2019

Embryonic damage due to autoantibodies could be cause of behavioral disorders in the child

Dysfunctions in the maternal immune system that occur during pregnancy could possibly lead to impaired brain development in the unborn child.

18 Sep 2019

ECLS trial demonstrates potential of blood test for early lung cancer detection

Oncimmune Holdings plc, a leading global immunodiagnostics group, welcomes the presentation of data today by Professor Frank Sullivan (Chief Investigator on the ECLS trial) which has demonstrated the potential of Oncimmune’s EarlyCDT Lung test to reduce the incidence of patients with late-stage lung cancer at diagnosis, compared with standard clinical diagnosis.

12 Sep 2019

First potential biomarker identified for postural orthostatic tachycardia syndrome

New research from The University of Toledo College of Medicine and Life Sciences strongly suggests postural orthostatic tachycardia syndrome, or POTS, is an autoimmune disorder and may help pave the way for a simple blood test that could help physicians diagnose the condition.

9 Sep 2019

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss.

8 Sep 2019

New circulating immune cell could help predict type 1 diabetes risk

A new Finnish study suggests that type 1 diabetes may in part be caused by a novel subset of immune cells. This is because these cells, called peripheral T helper cells, are found to circulate at a higher rate in children with type 1 diabetes of recent onset, as well as in healthy children who later develop the condition.

20 Aug 2019