Autoimmunity News and Research

RSS

Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Two-arm molecule can deplete cancer-protecting cells to promote immune responses against tumors

A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, could lead to new types of cancer immunotherapies.

11 Aug 2021

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

Immunohistochemistry staining showing PD1 expression on tumor cells in a skin biopsy from a cutaneous T-cell lymphoma patient.

5 Aug 2021

CD8+ T cells show gene-dependent variation in cross-reactivity to human coronaviruses

A new study discusses how both different responses to the infection itself and to COVID-19 vaccines are likely the result of genetic differences.

25 Jul 2021

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

You can't make a banana split without bananas. And you can't generate stable regulatory T cells without Vitamin C or enzymes called TET proteins, it appears.

21 Jul 2021

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

20 Jul 2021

Functional autoantibody in COVID-19 contributes to the 'firestorm' of blood clots and inflammation

Researchers at Michigan Medicine have discovered yet another functional autoantibody in COVID-19 patients that contributes to the disease's development and the "firestorm" of blood clots and inflammation it induces.

19 Jul 2021

UCSF researchers discover how the immune system may play a role in miscarriage

Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.

16 Jul 2021

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers.

16 Jul 2021

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

The National Institutes of Health has awarded the University of South Florida total expected funds of $69.9 million over the next four years to continue the follow-up of study participants in The Environmental Determinants of Diabetes in The Young (TEDDY) consortium.

13 Jul 2021

SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Researchers from Switzerland recently investigated humoral and cell-mediated immune responses to mRNA-based vaccines in patients undergoing treatment with CD20-B-cell depleting agents for autoimmune diseases, transplantation, or malignancy.

12 Jul 2021

Exposure to beneficial microorganisms is not affected by targeted hygiene or cleaning

The theory that modern society is too clean, leading to defective immune systems in children, should be swept under the carpet, according to a new study by researchers at UCL and the London School of Hygiene & Tropical Medicine.

5 Jul 2021

EULAR Patient Research Partners join in new research project to advance treatment of psoriatic arthritis

Eleven Patient Research Partners (PRPs) from three organizations (EULAR, GRAPPA-EU, and EUROPSO) participate in the new research project HIPPOCRATES, ensuring the patients' perspective is preserved and prioritized in all research activities to maximize the project's impact.

2 Jul 2021

Connective tissue protein promotes immune responses that fight bacterial infections

A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition called sepsis, a new study finds.

28 Jun 2021

UCLA scientists discover how immune cells can be trained to fight potential threats

The body's immune cells naturally fight off viral and bacterial microbes and other invaders, but they can also be reprogrammed or "trained" to respond even more aggressively and potently to such threats, report UCLA scientists who have discovered the fundamental rule underlying this process in a particular class of cells.

24 Jun 2021

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor of physiology & biophysics and member of the Institute for Immunology at the University of California, Irvine.

22 Jun 2021

A World First: sequencing polyclonal antibodies using only proteomics

News-Medical speaks to Bin Ma, President of Rapid Novor, about their latest research that sequenced polyclonal antibodies using only proteomics.

From Rapid Novor Inc 21 Jun 2021

Passive smoking and air pollution associated with arthritis risk, poor response to RA treatment

RA is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It can also cause fatigue, and the underlying inflammation may affect other body systems.

18 Jun 2021

Researchers assess the incidence of dementia or heart failure in people with rheumatoid arthritis

RA is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It can also cause fatigue, and the underlying inflammation may affect other body systems.

18 Jun 2021

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Genetics plays a major role in determining a person’s risk of developing type 1 diabetes, but environmental and lifestyle factors are also important. In an article recently published in Chinese Medical Journal, a team of researchers explore the interplay of genetic and environmental factors by summarizing the literature on type 1 diabetes and epigenetics—the study of how gene expression patterns can be modified.

18 Jun 2021

Study shows link between breast milk, gut bacteria, and development of the immune system

Many diseases caused by a dysregulated immune system, such as allergies, asthma and autoimmunity, can be traced back to events in the first few months after birth.

17 Jun 2021

Autoimmunity News and Research

Further Reading

Two-arm molecule can deplete cancer-protecting cells to promote immune responses against tumors

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

CD8+ T cells show gene-dependent variation in cross-reactivity to human coronaviruses

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

Functional autoantibody in COVID-19 contributes to the 'firestorm' of blood clots and inflammation

UCSF researchers discover how the immune system may play a role in miscarriage

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Exposure to beneficial microorganisms is not affected by targeted hygiene or cleaning

EULAR Patient Research Partners join in new research project to advance treatment of psoriatic arthritis

Connective tissue protein promotes immune responses that fight bacterial infections

UCLA scientists discover how immune cells can be trained to fight potential threats

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

A World First: sequencing polyclonal antibodies using only proteomics

Passive smoking and air pollution associated with arthritis risk, poor response to RA treatment

Researchers assess the incidence of dementia or heart failure in people with rheumatoid arthritis

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Study shows link between breast milk, gut bacteria, and development of the immune system

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News