Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

World-first discovery offers potential cure for lupus

Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.

6 Feb 2024

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Researchers uncover that the Xist ribonucleoprotein complex, unique to females, is a key driver of sex-biased autoimmunity, offering new insights into autoimmune disorders' higher prevalence in women.

4 Feb 2024

X-chromosome inactivation and its role in autoimmune susceptibility in females

Somewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our own tissues. As many as 4 out of 5 of those people are women.

1 Feb 2024

Study finds patients with long COVID exhibit complement dysregulation with signs of thromboinflammation

Researchers explore inflammatory signatures restricted to patients with active post-acute COVID-19 sequelae.

23 Jan 2024

New biomarkers could help detect lupus nephritis earlier

New biomarkers with improved diagnostic performance for early detection of lupus nephritis have been discovered in the University of Houston lab of Chandra Mohan, a pioneer in lupus research.

22 Jan 2024

Study shows slight increase in Guillain-Barre syndrome risk with adenovirus COVID vaccines

Study investigates the link between COVID-19 vaccines and autoimmune/neurological diseases, focusing on Guillain-Barre syndrome (GBS) risks associated with adenovirus vector vaccines.

16 Jan 2024

Defective gene triggers uncontrolled immune attack in young lupus patients

A group of researchers lead by Min Ae Lee-Kirsch from the Department of Pediatrics, Medical Faculty, TUD Dresden University of Technology (Germany), studied four patients from two families who developed symptoms of SLE in the first years of life.

12 Jan 2024

New molecule targets key protein in autoimmune diseases

Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease.

11 Jan 2024

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

19 Dec 2023

Unlocking the secrets of our "dark genome": Scientists crack the code of LINE-1

A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome" -; the 98 percent of our DNA that has largely unknown biological function.

14 Dec 2023

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

Inflammation is an important part of the body's defenses, eliminating threats and repairing damage. When the immune system is overactivated, though, it can turn from friend to foe.

14 Dec 2023

Study suggests possible targets for the development of a vaccine against multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease in which the Epstein-Barr virus (EBV) is thought to play a role that has not yet been fully clarified.

14 Dec 2023

ANU research uncovers protein's role in autoimmune disease and cancer

A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research from The Australian National University (ANU) has found.

6 Dec 2023

New study classifies CSU skin eruptions into five categories using mathematical modeling

Chronic spontaneous urticaria (CSU), a skin condition marked by sudden eruptions.

6 Dec 2023

Breakthrough research identifies new ways to target skin autoimmune diseases

Breakthrough research has revealed new ways to remove immune cells that cause skin autoimmune diseases without affecting protective cells that fight infection and cancer.

30 Nov 2023

Science tackles mental health: New tools against anxiety and depression in a stressed world

This review in the Proceedings of the National Academy of Sciences discusses the role of scientific tools in combating mental health disorders like anxiety, MDD, and PTSD, emphasizing the need for a deep scientific understanding and diverse treatment approaches in the face of a global surge in psychological stress. The study explores stress biology, treatment strategies, and the importance of personalized scientific approaches to effectively address the mental health crisis.

29 Nov 2023

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

A subtype of CD8 T cells, which are classically known to promote immune system responses, may be in fact regulating the immune system by suppressing immune cells causing self-destructive responses leading to autoimmune disorders and organ graft rejection.

15 Nov 2023

Autoimmunity News and Research

Further Reading

World-first discovery offers potential cure for lupus

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

X-chromosome inactivation and its role in autoimmune susceptibility in females

Study finds patients with long COVID exhibit complement dysregulation with signs of thromboinflammation

New biomarkers could help detect lupus nephritis earlier

Study shows slight increase in Guillain-Barre syndrome risk with adenovirus COVID vaccines

Defective gene triggers uncontrolled immune attack in young lupus patients

New molecule targets key protein in autoimmune diseases

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Unlocking the secrets of our "dark genome": Scientists crack the code of LINE-1

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

Study suggests possible targets for the development of a vaccine against multiple sclerosis

ANU research uncovers protein's role in autoimmune disease and cancer

New study classifies CSU skin eruptions into five categories using mathematical modeling

Breakthrough research identifies new ways to target skin autoimmune diseases

Science tackles mental health: New tools against anxiety and depression in a stressed world

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

Bacteria fight phages with RNA-based immune defense

New lipidic peptide IK14004 shows promise in treating cancer and reducing autoimmune complications

Allen Discovery Center for Neuroimmune Interactions launched at Mount Sinai

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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