Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

NIH awards grants to 11 research groups to establish AMP RA/Lupus Network

The National Institutes of Health has awarded grants to 11 research groups across the United States to establish the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus (AMP RA/Lupus) Network.

25 Sep 2014

Researchers discover new details of how autoantibodies destroy healthy cells in skin

University at Buffalo researchers and colleagues studying a rare, blistering disease have discovered new details of how autoantibodies destroy healthy cells in skin.

11 Sep 2014

Belgian receives research grant from Jeffrey Modell to help cure IPEX syndrome

For the first time the Jeffrey Modell Foundation is giving a research grant to a Belgian laboratory. The team of Adrian Liston from VIB-KU Leuven will use the grant to develop a gene therapy to cure children that suffer from IPEX syndrome, a rare and fatal autoimmune disorder in which the immune system attacks the body's own tissues and organs.

9 Sep 2014

New biomarker may improve diagnosis of early-stage rheumatoid arthritis

A novel biomarker for rheumatoid arthritis (RA) has significant potential to help physicians better identify early-stage disease, when treatment can often arrest further disease progression and disability, according to a new study in The Journal of Rheumatology.

From Quest Diagnostics 28 Aug 2014

Study identifies novel gene that controls nerve conduction velocity linked with MS

A new study published in The American Journal of Pathology identifies a novel gene that controls nerve conduction velocity.

13 Aug 2014

Immune system play role in memory impairment associated with chronic epilepsy

Could the body's own immune system play a role in memory impairment and cognitive dysfunction associated with conditions like chronic epilepsy, Alzheimer's dementia and concussions? Cleveland Clinic researchers believe so, based on a study published online by PLOS ONE.

25 Jul 2014

Researchers discover how metal beryllium triggers deadly immune response in the lungs

Using exquisitely detailed maps of molecular shapes and the electrical charges surrounding them, researchers at National Jewish Health have discovered how the metal beryllium triggers a deadly immune response in the lungs.

3 Jul 2014

Australian immunologists uncover additional role for antibody-making 'B cells'

A discovery by Australian immunologists, uncovering an additional role for antibody-making 'B cells', is considered important enough by the American Association of Immunologists to rank it among the top 10% of articles in the latest issue of The Journal of Immunology, off the press today.

2 Jul 2014

Researchers find unique cell type that can protect against uveitis

Researchers at the National Eye Institute (NEI) have found a unique cell type that, in tests on mice, can protect against uveitis—a group of inflammatory diseases that affect the eye and can cause vision loss.

1 Jul 2014

Researchers find shared genetic link in autoimmune response among PV patients

Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.

19 Jun 2014

No link between consumption of cow's milk-based formula and development of autoantibodies in kids

There is no correlation between the consumption of a cow's milk-based formula or hydrolyzed protein formula and the development of diabetes-associated autoantibodies in children younger than seven, according to a worldwide research study published in the Journal of the American Medical Association (JAMA).

17 Jun 2014

Scientists identify novel approach to treating multiple sclerosis

Scientists in the University of Connecticut's Technology Incubation Program have identified a novel approach to treating multiple sclerosis (MS) using human embryonic stem cells, offering a promising new therapy for more than 2.3 million people suffering from the debilitating disease.

17 Jun 2014

Using placental cells to repair damaged tissues: an interview with Zami Aberman, CEO, Pluristem Therapeutics

We start with birth and we collect the cells after C-section. The reason for that is we have to have the mother sign a consent letter that she is donating the placenta and, on top of that, we have to have a blood sample from the mother to test for any viral contamination.

16 Jun 2014

Hydrolyzed formula does not lower diabetes linked autoantibodies in infants at risk for type 1 diabetes

Among infants at risk for type 1 diabetes, the use of a hydrolyzed formula (one that does not contain intact proteins) compared with a conventional formula did not reduce the incidence of diabetes-associated autoantibodies after 7 years of follow-up, according to a study in the June 11 issue of JAMA, a diabetes theme issue.

11 Jun 2014

Findings add surprising new dimension to understanding of antibody repertoires

As elite soldiers of the body's immune response, B cells serve as a vast standing army ready to recognize and destroy invading antigens, including infections and cancer cells. To do so, each new B cell comes equipped with its own highly specialized weapon, a unique antibody protein that selectively binds to specific parts of the antigen.

10 Jun 2014

Wistar findings suggest means of boosting initial immune response

Your first response to an infectious agent or antigen ordinarily takes about a week, and is relatively weak. However, if your immune system encounters that antigen a second time, the so-called memory response is rapid, powerful, and very effective.

10 Jun 2014

FCVB 2014 to feature cutting edge research in basic cardiovascular science

Cutting edge research in basic cardiovascular science will be presented at Frontiers in CardioVascular Biology (FCVB) 2014, held 4-6 July at the Palau de Congressos de Catalunya in Barcelona, Spain.

5 Jun 2014

TCM announces winners of 26th Annual Industry Awards

The Tech Council of Maryland (TCM), Maryland's largest technology trade association for life science and technology, today announced the winners of its 26th Annual Industry Awards.

16 May 2014

Baylor receives $3.3M grant from NIAMS to advance research in autoimmune diseases

Baylor Research Institute has received a $3.3 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), one of the National Institutes of Health, to fund its Autoimmunity Center of Excellence.

14 May 2014

Study provides insight into effects of interleukin-27 in regulatory T-cell biology, physiological functions of IL-27

In a new report published in the Journal of Leukocyte Biology, scientists lay the groundwork for the development of novel tumor therapies that may help rid the body of cancer by inhibiting the recruitment of a specific suppressive immune cell type called "regulatory T-cells." The approach described in the report shows that an immune molecule, called interleukin-27, promotes the recruitment of regulatory T-cells.

2 May 2014