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New model of esophageal cancer

In the November 1st issue of G&D, a team of scientists led by Dr. Anil Rustgi (UPENN) presents an innovative new model of esophageal cancer, which holds great promise as an experimental platform to investigate the etiology and possible treatment of this devastating disease.

1 Nov 2007

Vitamin A derivative associated with reduced growth in some lung cells

Treatment with a derivative of vitamin A called retinoic acid was associated with reduced lung cell growth in a group of former heavy smokers, according to a study published online October 30 in the Journal of the National Cancer Institute.

31 Oct 2007

Cancer fighting technology uses UV light to attack tumours

Scientists at Newcastle University have developed a cancer fighting technology which uses UV light to activate antibodies which very specifically attack tumours.

31 Oct 2007

Daily commute in car increases exposure to harmful air pollutants

The daily commute may be taking more of a toll than people realize. A new study by researchers at the University of Southern California (USC) and the California Air Resources Board found that up to half of Los Angeles residents' total exposure to harmful air pollutants occurs while people are traveling in their vehicles.

31 Oct 2007

No link between vitamin D and overall cancer deaths

No relationship was found between vitamin D levels and the overall risk of dying from cancer, according to a study published online October 30 in the Journal of the National Cancer Institute.

31 Oct 2007

Neural stem cells may help to restore memory after brain damage

In the study, mice with brain injuries experienced enhanced memory -- similar to the level found in healthy mice -- up to three months after receiving a stem cell treatment. Scientists believe the stem cells secreted proteins called neurotrophins that protected vulnerable cells from death and rescued memory.

31 Oct 2007

Scripps design new type of vaccine that could one day be used in humans to block the onset of infection

In hopes of combating the growing scourge of antibiotic-resistant bacteria, in particular drug-resistant staph bacteria, a team of scientists from the Scripps Research Institute has designed a new type of vaccine that could one day be used in humans to block the onset of infection.

31 Oct 2007

Herb rosemary fights free radical damage in the brain

Rosemary not only tastes good in culinary dishes such as Rosemary chicken and lamb, but scientists have now found it is also good for your brain.

31 Oct 2007

Novel strategy to inactivate encephalitis virus

A collaborative team of scientists from the Uniformed Services University of the Health Sciences (USU) and the National Cancer Institute (NCI) have developed a novel strategy to inactivate highly virulent Venezuelan equine encephalitis virus (VEEV) that can infect and kill both animals and humans.

31 Oct 2007

Quality of life most important for survival in advanced non-small cell lung patients

Healthcare providers have observed it for years -- patients who appear to have a better quality of life while battling their cancer live longer.

31 Oct 2007

Light beams used as tweezers to manipulate cells

In a feat that seems like something out of a microscopic version of Star Trek, MIT researchers have found a way to use a "tractor beam" of light to pick up, hold, and move around individual cells and other objects on the surface of a microchip.

31 Oct 2007

How tumors respond to EGFR inhibitors

Three papers published this month in the open access general medical journal PLoS Medicine investigate how tumors respond to a an important class of drugs used in cancer chemotherapy, known as epidermal growth factor receptor (EGFR) inhibitors.

31 Oct 2007

Cancers successfully treated by targeting the viruses that cause them

Researchers at the Albert Einstein College of Medicine of Yeshiva University have shown for the first time that cancers can be successfully treated by targeting the viruses that cause them.

31 Oct 2007

Blood group O may be the key to a cure for malaria

New research from Scotland has led to a discovery which may bring a cure for malaria a step closer.

31 Oct 2007

Vitamin D protects against colorectal cancer

According to a new study by researchers at the U.S. National Cancer Institute (NCI) there is no link between vitamin D levels and the overall risk of dying from cancer.

31 Oct 2007

Aggregation propensity, amyloid peptide toxicity and Alzheimer disease

Cells have evolved multiple mechanisms to ensure proper folding, but a number of molecular and biophysical events - such as changes in pH or temperature, mutations, and oxidation - can disrupt a protein's native shape.

31 Oct 2007

New Jersey appellate court rules referendum asking voters to approve $450M for stem cell research should remain on ballot

A three-judge panel of a New Jersey appellate court on Friday unanimously ruled that a Nov. 6 referendum that would allow the state to borrow $450 million over 10 years to fund stem cell research in the state should not be removed from the ballot, the New York Times reports (Peters, New York Times, 10/27).

30 Oct 2007

Saint Louis University scientists identify chemical that triggers Parkinson's disease

Researchers at the Saint Louis University School of Medicine have discovered the key brain chemical that causes Parkinson's disease - a breakthrough finding that could pave the way for new, far more effective therapies to treat one of the most common and debilitating neurological disorders.

30 Oct 2007

Copper transporter plays an unexpected role in the absorption of cisplatin

Platinum complexes such as the well-known cisplatin are powerful antitumor medications. They cross the cell membrane and reach the nucleus, where they attach to DNA and stop cell growth. But how does cisplatin get to the nucleus?

30 Oct 2007

What makes some clays powerful antimicrobial agents?

With funding from the National Institutes of Health-National Center for Complementary and Alternative Medicine, the UB geologists are studying the surface characteristics of a broad range of naturally occurring antimicrobial clays, including some clays from France to determine why they are such effective killers of bacteria.

29 Oct 2007