B Cell News and Research

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Checkpoint inhibitors may not be effective lymphoma treatment when CAR T fails

For 30% to 40% of lymphoma patients who receive CAR T therapy, the treatment is a godsend.

25 Apr 2023

Deciphering immunological imprinting in the context of COVID-19

In a recent article published in the journal Immunity, researchers explained the concept of immunological imprinting and its underlying principles. They also discussed its potential role in the context of coronavirus disease 2019 (COVID-19) vaccines.

24 Apr 2023

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Researchers explored the pathophysiological variables and coagulation abnormalities associated with long coronavirus disease (COVID).

21 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

B cells use mechanical force to pull antigen molecules off other cells

Most cells evolve slowly, accumulating incremental changes that better suit their environments. Immune cells, because they must adapt rapidly to counter new threats, evolve much more quickly.

13 Apr 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

12 Apr 2023

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

A new nuclear medicine therapy can cure human non-Hodgkin lymphoma in an animal model, according to research published in the April issue of The Journal of Nuclear Medicine.

11 Apr 2023

Regulatory T cell populations descend from two different origins, finds study

A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's Hospital of Philadelphia (CHOP).

7 Apr 2023

Study explains why leukemia survivors experience negative effects on blood formation decades later

Contrary to previous belief, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia.

5 Apr 2023

Updated booster shots vital for keeping COVID-19 in check

Between natural infection and a global vaccination campaign, most people now have some immunity against the virus that causes COVID-19.

3 Apr 2023

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

A study published in Cell Reports Medicine describes that COVID-19 vaccines induce strong T cell response in blood cancer patients, irrespective of antibody response and B cell numbers.

30 Mar 2023

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer.

29 Mar 2023

Hematology patients generate robust immune responses against SARS-CoV-2 after vaccination

Researchers found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

29 Mar 2023

New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

Researchers isolate an IgM exhibiting ultrapotent neutralization from a Zika virus-infected pregnant woman

A recent study published in the Cell Press Journal demonstrated that plasma immunoglobulins of isotype M elicited during pregnancy have an exceptional Zika virus-neutralizing potential.

27 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

B Cell News and Research

Checkpoint inhibitors may not be effective lymphoma treatment when CAR T fails

Deciphering immunological imprinting in the context of COVID-19

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

B cells use mechanical force to pull antigen molecules off other cells

New tool provides insight into the developmental history of certain immune cells

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

Regulatory T cell populations descend from two different origins, finds study

Study explains why leukemia survivors experience negative effects on blood formation decades later

Updated booster shots vital for keeping COVID-19 in check

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

Hematology patients generate robust immune responses against SARS-CoV-2 after vaccination

New study suggests broad neutralizing antibody could provide three years of COVID protection

Researchers isolate an IgM exhibiting ultrapotent neutralization from a Zika virus-infected pregnant woman

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Detecting tissue-resident memory T cells in solid tumors

Immunochemistry multiplex for solid tumor analytical validation

Analyzing regulatory and effector T cells in tumors

Immunology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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