Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New advance in the development of a test for early diagnosis of cancer

Blood cells reveal tumors in the body. Researchers at the Paul Scherrer Institute achieve an advance with the development of a test for early diagnosis of cancer.

14 Dec 2023

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Researchers performed a two-sample Mendelian randomization analysis to investigate the associations between genetically proxied suppression of PDE5, a recognized pharmacological target for erectile dysfunction, fertility, subjective wellness, and sexual behavior.

14 Dec 2023

Epigenetic changes can contribute to the development of type 2 diabetes

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.

13 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

PharmaKure and Universiti Teknologi MARA (UiTM) announce partnership to advance research in Alzheimer’s Disease diagnosis

Research partnership aims to build strong pharma and academic collaborations in sharing data and clinical samples to develop biomarker-based diagnostics for Alzheimer’s Disease.

12 Dec 2023

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV).

11 Dec 2023

Can oral contraceptive therapy improve the vaginal microbiome in women with PCOS?

The impact of the contraceptive medication-induced change in hormonal levels on the vaginal microbiome.

7 Dec 2023

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Researchers performed a proteomic analysis to identify serologic indicators of organ aging and disease.

7 Dec 2023

Mediterranean diet linked to improved sperm quality

A study in the journal Nutrients finds that adherence to the Mediterranean diet positively correlates with improved sperm parameters in men. This observational cross-sectional study, involving 300 non-obese males, revealed that higher adherence to the diet is associated with better sperm motility, morphology, viability, and count, suggesting that diet can be a crucial factor in male fertility.

5 Dec 2023

Study identifies genetic indicators to predict the decline of cognitive abilities

For some people, extreme stressors like psychiatric disorders or childhood neglect and abuse can lead to a range of health problems later in life, including depression, anxiety and cardiovascular disease.

5 Dec 2023

New biomarker for inflammatory bowel disease identified through reverse metabolomics

In recent years, microbiome research has started to shift its focus from the microbes themselves to the molecules they produce.

5 Dec 2023

Brain imaging and machine learning identify altered functional brain connectivity in people with ASD

What happens in the brain to cause many neurodevelopmental disorders, including autism spectrum disorder (ASD), remains a mystery.

5 Dec 2023

Study delves into the molecular intricacies of osteosarcoma in elderly patients

In a study published in the journal Genes & Diseases, scientists from Union Hospital, Tongji Medical College, and Huazhong University of Science and Technology delve into the molecular intricacies of osteosarcoma in the elderly.

4 Dec 2023

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice.

30 Nov 2023

Machine learning model predicts brain health improvements based on neural biomarkers

As part of its ongoing quest to advance better brain health and performance, new research led by Center for BrainHealth at The University of Texas at Dallas investigated neural biomarkers associated with improvements on a brain health index.

30 Nov 2023

Mapping emotions in the body: Study reveals physical topography of feelings

The study published in PNAS reveals that emotions create identifiable maps of bodily sensations, consistent across different cultures and races. Using a novel method named "embody," researchers found that subjective emotional experiences are linked to specific bodily changes, providing insights that could aid in understanding and treating mood disorders like depression and anxiety, which alter standard emotional processing.

30 Nov 2023

Non-invasive monitoring of glucose and adenosine monophosphate biomarkers in saliva

Dr Farid Khan, PharmaKure CEO, to speak on Alzheimer's diagnosis and treatment at Biotech Outsourcing Strategies Manchester 2023

Talk to focus on the spinout journey from drug repurposing to clinical trials for diagnosing and treating Alzheimer’s Disease.

28 Nov 2023

Biomarker News and Research

Further Reading

New advance in the development of a test for early diagnosis of cancer

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Epigenetic changes can contribute to the development of type 2 diabetes

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

PharmaKure and Universiti Teknologi MARA (UiTM) announce partnership to advance research in Alzheimer’s Disease diagnosis

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Can oral contraceptive therapy improve the vaginal microbiome in women with PCOS?

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Mediterranean diet linked to improved sperm quality

Study identifies genetic indicators to predict the decline of cognitive abilities

New biomarker for inflammatory bowel disease identified through reverse metabolomics

Brain imaging and machine learning identify altered functional brain connectivity in people with ASD

Study delves into the molecular intricacies of osteosarcoma in elderly patients

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Machine learning model predicts brain health improvements based on neural biomarkers

Mapping emotions in the body: Study reveals physical topography of feelings

Non-invasive monitoring of glucose and adenosine monophosphate biomarkers in saliva

Imaging approach provides objective evidence for the involvement of neck muscles in primary headaches

Clinical trial reveals dapagliflozin's impact on heart failure and type 2 diabetes management

Dr Farid Khan, PharmaKure CEO, to speak on Alzheimer's diagnosis and treatment at Biotech Outsourcing Strategies Manchester 2023

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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