Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study links OCD improvement to brain activity shift

A recent study from Baylor College of Medicine and Texas Children's Hospital has identified a specific neural activity pattern as a novel biomarker to accurately predict and monitor the clinical status of individuals with obsessive-compulsive disorder (OCD) who have undergone deep brain stimulation (DBS), a rapidly emerging therapeutic approach for severe psychiatric disorders. The study, led by led by Drs. Sameer Sheth and Wayne Goodman along with co-lead authors, Drs. Nicole Provenza, Sandy Reddy, and Anthony Allam, was published in Nature Medicine.

13 Jul 2024

New threshold for CXCL13 concentration revolutionizes neuroborreliosis diagnosis

A newly defined threshold for the concentration of the cytokine CXCL13 may improve the diagnosis of neuroborreliosis.

13 Jul 2024

How lipoproteins shape your metabolic health

Study provides a comprehensive review of the lipoprotein pathway and its impact on healthy metabolism, highlighting the roles of HDL, LDL, and other lipoproteins in cardiovascular health and disease.

11 Jul 2024

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

A recent meta-analysis in Nutrients examined recent studies on the cornelian cherry, Cornus mas L., for evidence of its cardiometabolic benefit.

11 Jul 2024

High-intensity interval exercise improves brain function in older adults

A longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in older adults for up to 5 years.

10 Jul 2024

Novel device uses a simple blood test to detect early stage lung cancer

University of Queensland researchers have designed a device that uses a simple blood test to detect early stage lung cancer.

10 Jul 2024

New 'band-aid' measures body biomarkers that indicate health or disease through sweat

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a 'band-aid' or plaster that measures body 'biomarkers' that can indicate health or disease through sweat, paving the way for a new non-invasive and effective way for patients to monitor their health.

8 Jul 2024

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

Researchers developed an AI model using multimodal data to accurately diagnose different types of dementia, enhancing early and personalized treatment.

8 Jul 2024

Turning cancer cells against themselves to overcome drug resistance

Treating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians never know when, where and what resistance might emerge, leaving them one step behind.

4 Jul 2024

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed.

3 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

No organ is an island: Genetic study shows unique but interconnected aging markers

Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.

2 Jul 2024

Study sheds light on the intricate relationship between depression and brain activity

A significant new study published in the Cyborg Bionic Systems journal by Fanli Kong and colleagues sheds light on the intricate relationship between depression and brain activity, particularly focusing on the basolateral amygdala (BLA) in rats.

26 Jun 2024

AI transforming cardiovascular care with groundbreaking diagnostic and prognostic innovations

AI tools are revolutionizing cardiovascular healthcare by enhancing diagnostics, prognostics, and biomarker detection, thus improving the precision and efficacy of care. The review also addresses the potential risks and challenges in integrating AI into clinical workflows.

25 Jun 2024

Breakthrough biomarker predicts recurrence risk in clear cell renal cancer

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence.

25 Jun 2024

Pentraxin 3 as a predictor of advanced fibrosis and carotid intima-media thickness in MAFLD patients

Metabolic-associated fatty liver disease (MAFLD) may increase the risk of cardiovascular events. In this study, we assessed the predictive value of pentraxin 3 (PTX3) for severe fibrosis and carotid intima-media thickness (CIMT) in patients with MAFLD.

25 Jun 2024

FDA expands orphan drug designation for Roswell Park's brain cancer immunotherapy

The U.S. Food and Drug Administration (FDA) has expanded orphan drug designation for SurVaxM, a brain cancer immunotherapy born in the labs of Roswell Park Comprehensive Cancer Center.

25 Jun 2024

SPT Labtech and Olink Announce New Automated Solution to Accelerate Research with Olink Next Generation Proteomics Technology

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From SPT Labtech 25 Jun 2024

Research shows gut bacteria's role in mental resilience and reduced anxiety

Researchers characterized brain-gut microbiome (BGM) patterns related to stress resilience.

25 Jun 2024

Electrophysiological markers for personalizing transcranial magnetic stimulation in depression

Not all patients with depression respond to medication. Two recently published studies provide additional information on how an alternative treatment, transcranial magnetic stimulation (TMS), could be further enhanced.

24 Jun 2024

Biomarker News and Research

Further Reading

Study links OCD improvement to brain activity shift

New threshold for CXCL13 concentration revolutionizes neuroborreliosis diagnosis

How lipoproteins shape your metabolic health

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

High-intensity interval exercise improves brain function in older adults

Novel device uses a simple blood test to detect early stage lung cancer

New 'band-aid' measures body biomarkers that indicate health or disease through sweat

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

Turning cancer cells against themselves to overcome drug resistance

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

White blood cell type identified as important contributor to inflammation in obesity

No organ is an island: Genetic study shows unique but interconnected aging markers

Study sheds light on the intricate relationship between depression and brain activity

AI transforming cardiovascular care with groundbreaking diagnostic and prognostic innovations

Breakthrough biomarker predicts recurrence risk in clear cell renal cancer

Pentraxin 3 as a predictor of advanced fibrosis and carotid intima-media thickness in MAFLD patients

FDA expands orphan drug designation for Roswell Park's brain cancer immunotherapy

SPT Labtech and Olink Announce New Automated Solution to Accelerate Research with Olink Next Generation Proteomics Technology

Research shows gut bacteria's role in mental resilience and reduced anxiety

Electrophysiological markers for personalizing transcranial magnetic stimulation in depression

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