Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Therapeutic ketosis for mild cognitive impairment, Alzheimer's and Parkinson's

A new study in Frontiers in Neurology aimed to review the available studies which support the clinical utility of ketogenic interventions in PD, MCI, and AD.

5 Mar 2023

Pitt and UCI researchers secure funding to advance understanding of patient reactions to Alzheimer's diagnoses

University of Pittsburgh and University of California, Irvine (UCI) researchers have received funding from the National Institute of Aging to advance understanding of real-world patient and family member reactions to biomarker-informed Alzheimer's disease and related disorders diagnoses.

3 Mar 2023

Association between cardiovascular disease and transportation noise revealed in new research

Researchers assessed the association between cardiovascular disease and transportation noise.

3 Mar 2023

Astrocytes exhibit stronger acid response with REM sleep in epileptic mice

Researchers at Tohoku University have shown that astrocytes - star-shaped glial cells that control the local ionic and metabotropic environment of the brain - exhibit an acid response with REM sleep in mice.

3 Mar 2023

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Researchers assessed the role of renalase as an independent predictor of COVID-19-related mortality.

2 Mar 2023

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

In a recent study posted to the Preprints with The Lancet SSRN* server, a team of researchers in China developed a machine learning-based diagnostic tool to detect tuberculosis and drug-resistant tuberculosis using nanoparticle-enhanced laser desorption/ionization mass spectrometry (NPELDI MS) to determine metabolic fingerprints from serum samples.

28 Feb 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

An overview of the anti-inflammatory effects of nuts

Researchers summarize existing literature on the effects of consuming nuts on biomarkers of inflammation and oxidative stress.

28 Feb 2023

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

Published in JAMA, a University of Minnesota led study shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes (T1D).

24 Feb 2023

The relationship between DNAm-based age acceleration measures in the prediction of cross-sectional and longitudinal health outcomes and mortality

Researchers assessed the association between deoxyribonucleic acid methylation (DNAm)-based clocks or aging measures and demographic and serological parameters in estimating health-associated outcomes, including deaths.

24 Feb 2023

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Cedars-Sinai investigators found that women who developed mood and anxiety disorders associated with pregnancy and childbirth had specific altered proteins circulating in their bloodstream in the third trimester.

23 Feb 2023

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Measuring a key blood molecule may help doctors diagnose whether or how much impaired blood flow to a patient's brain is contributing to dementia or cognitive problems, according to a new study led by a UCLA Health researcher.

23 Feb 2023

First molecular biomarker for acquired generalized lipodystrophy discovered

Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.

21 Feb 2023

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

In new evidence-based guidelines, the American Gastroenterological Association recommends non-invasive biomarkers as a first-line strategy for monitoring many patients with ulcerative colitis (UC).

21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Biomarker News and Research

Further Reading

Therapeutic ketosis for mild cognitive impairment, Alzheimer's and Parkinson's

Pitt and UCI researchers secure funding to advance understanding of patient reactions to Alzheimer's diagnoses

Association between cardiovascular disease and transportation noise revealed in new research

Astrocytes exhibit stronger acid response with REM sleep in epileptic mice

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

Mass spectrometry-based identification of COVID-19 biomarkers

An overview of the anti-inflammatory effects of nuts

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

The relationship between DNAm-based age acceleration measures in the prediction of cross-sectional and longitudinal health outcomes and mortality

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

First molecular biomarker for acquired generalized lipodystrophy discovered

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Study examines link between different epigenetic age measures and lung cancer risk

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Neoadjuvant nivolumab treatment improves survival rates in NSCLC patients

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

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