Celiac Disease News and Research

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Celiac disease is an inherited autoimmune disorder where gluten has been identified as the environmental trigger of the disease. Gluten is an ingested protein found in wheat, barley and rye. Gluten is broken down into gliadin which can pass through the intestinal epithelial barrier during times of increased intestinal permeability. The ingestion of gluten causes an immune response which triggers an inflammatory reaction in the small intestine. This then causes damage to the villi in the small intestine and can lead to total villous atrophy in celiac disease. This results in varying symptoms such as fatigue, skin rash, anemia, fertility issues, joint pain, weight loss, pale sores inside the mouth, tooth discoloration or loss of enamel, depression, chronic diarrhea or constipation, gas and abdominal pain. The immunology and nutritional abnormalities in celiac disease can potentially result in long- term complications such as osteoporosis, refractory sprue, small intestinal cancer, and lymphoma.

Celiac disease is a growing public health concern, affecting approximately 3 million people in the United States and over 6.5 million people worldwide. The only current management of celiac disease is complete elimination of gluten from the diet, which can be very difficult to implement in practice. Additionally, the response to the gluten-free diet is poor in up to 30% of patients, and dietary nonadherence is the chief cause of persistent or recurrent symptoms.
Leaky gut and space flight – the mechanism revealed

Leaky gut and space flight – the mechanism revealed

Novel diagnostic method for rapid measurement of celiac disease antibodies

Novel diagnostic method for rapid measurement of celiac disease antibodies

Space travel can affect intestinal function of astronauts

Space travel can affect intestinal function of astronauts

Tips for a gluten-free Thanksgiving dinner

Tips for a gluten-free Thanksgiving dinner

MU researchers describe Down syndrome-associated catatonia

MU researchers describe Down syndrome-associated catatonia

New insights into how immune system and inflammation play a role in PD

New insights into how immune system and inflammation play a role in PD

Celiac disease may now be curable with biodegradable nanoparticles

Celiac disease may now be curable with biodegradable nanoparticles

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

New treatment shows promise to reverse celiac disease

New treatment shows promise to reverse celiac disease

Healthiest gut bacteria with plant-based or Mediterranean diet

Healthiest gut bacteria with plant-based or Mediterranean diet

Research finds lower bone density among adults with undiagnosed celiac disease

Research finds lower bone density among adults with undiagnosed celiac disease

Kids with celiac disease and allergic inflammatory disorder may not need to remove soy from their diets

Kids with celiac disease and allergic inflammatory disorder may not need to remove soy from their diets

New study finds no significant gluten transfer in common-cooking activities of celiac families

New study finds no significant gluten transfer in common-cooking activities of celiac families

New AGA guideline on evaluation of chronic diarrhea released

New AGA guideline on evaluation of chronic diarrhea released

Diarrhea linked significantly to weight gain

Diarrhea linked significantly to weight gain

Raising Awareness of Coeliac Disease with Coeliac UK

Raising Awareness of Coeliac Disease with Coeliac UK

Discovery may help identify signs of type 1 diabetes earlier

Discovery may help identify signs of type 1 diabetes earlier

Study calls for screening of all first-degree relatives of celiac disease patients

Study calls for screening of all first-degree relatives of celiac disease patients

Type 1 diabetes linked to gut microbiome and genetic factors

Type 1 diabetes linked to gut microbiome and genetic factors

Genetic risk for autoimmunity may be linked to differences in gut microbiome

Genetic risk for autoimmunity may be linked to differences in gut microbiome