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Novel sequencing method could be useful for COVID-19 research

Researchers at the University of Chicago and the Cleveland Clinic have presented a novel single-cell RNA sequencing method that could be a useful application for research into the current coronavirus disease 2019 (COVID-19) pandemic.

20 Sep 2020

Engineered, high-affinity ACE2 receptors neutralize SARS-CoV-2

In a study published in the preprint server bioRxiv, researchers from the Kyoto Prefectural University of Medicine and Osaka University Japan, discuss how they engineered ACE2 to enhance its affinity to RBD in human cells.

17 Sep 2020

SMART researchers discover a new way to manufacture human red blood cells

Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have discovered a new way to manufacture human red blood cells (RBCs) that cuts the culture time by half compared to existing methods and uses novel sorting and purification methods that are faster, more precise and less costly.

14 Sep 2020

Study reveals how B cells react to SARS-CoV-2

In an exciting immunological medRxiv preprint paper, researchers from Germany and Russia analyzed adaptive immune response in severely affected patients with coronavirus disease (COVID-19). They demonstrated a protracted immune reaction characterized by egress of B lymphocytes into the blood.

9 Sep 2020

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot keep pace.

31 Aug 2020

Study suggests memory B cells persist following COVID-19 recovery

Researchers at Tel Aviv University in Israel have gained valuable insights into the serological and B cell response to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

26 Aug 2020

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

A seminal study by US researchers, currently available on the bioRxiv* preprint server, demonstrates how structure-based design can be efficiently employed to develop molecular probes targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike and its domains, with possible future use in diagnostics, treatment and vaccine development.

24 Jun 2020

Study reveals novel mechanism that triggers a cell-mediated immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that specifically recognize parts of the invading microbe and mediate its destruction.

11 Jun 2020

CBD treatment improves arthritis symptoms in dogs, study finds

A team led by researchers at Baylor College of Medicine in collaboration with Medterra CBD conducted the first scientific studies to assess the potential therapeutic effects of cannabidiol for arthritic pain in dogs, and the results could lead the way to studying its effect in humans.

28 May 2020

IONTAS announces a new collaboration to identify novel immunotherapy targets

Antibody discovery agreement will support the development of new therapeutics for acute and chronic inflammatory syndromes.

From FairJourney Biologics 7 May 2020

Study: Astrocytes regulate neuronal circuits involved in learning and memory

Researchers at Baylor College of Medicine reveal that astrocytes, the most abundant cells in the brain, play a direct role in the regulation of neuronal circuits involved in learning and memory. The findings appear in the journal Neuron.

24 Apr 2020

Scientists find a way to block the growth of kidney cancer

Scientists at the MDC have discovered stem cells responsible for the most common form of kidney cancer. The team of Walter Birchmeier has found a way to block the growth of these tumors in three models of the disease.

17 Feb 2020

Prenatal single cell blood test for gene defects

With the current state of knowledge regarding genetic testing, non-invasive prenatal testing (NIPT) is in favor for genetic testing in unborn babies, using fragments of DNA circulating in the mother’s blood.

4 Feb 2020

Single-cell DNA assessment method can detect fetal genetic abnormalities

Non-invasive prenatal tests are used for fetal genetic disease screening in pregnant women. In contrast, invasive tests like amniocentesis carry the risk of causing fetal harm.

4 Feb 2020

Study uncovers large, giant viruses that belong to NCLDV supergroup

While the microbes in a single drop of water could outnumber a small city's population, the number of viruses in the same drop-;the vast majority not harmful to humans could be even larger.

24 Jan 2020

Finding ways to stop cancer at its roots

Why do some cancers come back? Sometimes, a treatment can effectively eliminate cancer cells to undetectable levels, but, if the treatment stops, cancer may return.

7 Nov 2019

Oxygen-deprived tumor cells have survival advantage that promotes metastasis

Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream.

7 Nov 2019

Advances in translational genetics unlocked by Bio-Rad technologies to be presented at ASHG 2019

Scientists will present 24 abstracts and three talks, highlighting research driven in part by Bio-Rad Laboratories' Droplet Digital PCR and single-cell ATAC-Seq (scATAC-Seq) technologies, at the 2019 American Society of Human Genetics Annual Meeting in Houston, October 15-19.

15 Oct 2019

Researchers find diverse immune cell profiles, roles in breast cancer resistance to immunotherapy

In recent years it has been increasingly appreciated that immune cells within the tumor microenvironment contribute to tumor progression and, importantly, to the tumor's response to therapy.

27 Aug 2019

Johns Hopkins researchers use nanotechnology to repair faulty brain circuits

Working with mouse and human tissue, Johns Hopkins Medicine researchers report new evidence that a protein pumped out of some — but not all — populations of “helper” cells in the brain, called astrocytes, plays a specific role in directing the formation of connections among neurons needed for learning and forming new memories.

31 Jul 2019