Chemokine News and Research

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Chemokines are a family of small cytokines, or proteins secreted by cells. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3-dimensional shape.

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

22 Feb 2024

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals how smoking, CMV latent infection, and BMI significantly influence cytokine release, impacting immune response variability and potentially affecting disease risk.

14 Feb 2024

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

The effect of Interleukin-24 (IL-24) on CSCs and CAR-T cell therapy.

14 Feb 2024

Never-before-documented genetic disorder causes rare lung disease

The macrophage is one of the body's most important inhabitants. Meaning "big eater" in Greek, this immune cell consumes and digests problematic elements from microbes and cancer cells to dust and debris.

8 Feb 2024

Immune cells in overdrive: Study finds unbalanced response worsens lung infections

CD4+ T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections.

8 Feb 2024

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

Study reveals SARS-CoV-2 fragments mimic immune peptides, potentially driving the virus's inflammatory response, offering insights into COVID-19's severe inflammation mechanisms.

5 Feb 2024

Small-molecule A485 mobilizes white blood cells on demand

New study reveals a small molecule that can selectively mobilize white blood cells, offering potential treatments for diseases with abnormal leukocyte counts.

3 Feb 2024

Study reveals new mechanisms involved in the development of inflammatory cardiovascular diseases

A team led by LMU researchers Christian Weber and Yvonne Döring has demonstrated new mechanisms that are involved in the development of inflammatory cardiovascular diseases.

24 Jan 2024

COVID-19-associated blood plasma inflammatory factors do not affect blood-brain barrier, study shows

It is now well documented that the coronavirus outbreak triggered a global health crisis. In this study, researchers wanted to know whether blood-brain barrier impairment contributed to the development of neurological problems during COVID-19 progression, and to what extent.

19 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Unlocking the anti-inflammatory secrets of bergamot byproducts

The positive effect of bergamot derivatives.

17 Jan 2024

Immune dysregulation in long COVID patients uncovered in new study

Sstudy reveals significant immune changes in long COVID patients, including altered T cell responses and systemic inflammation, using advanced 'omics' and serological assays.

14 Jan 2024

Study: Respiratory syncytial virus directly infects nerve cells and causes inflammation

Respiratory syncytial virus (RSV), a common infection in children and senior adults, can also infect nerve cells and trigger inflammation leading to nerve damage, according to a new Tulane University study.

10 Jan 2024

Gut microbiota linked to social anxiety behaviors

Study reveals that gut microbiota from individuals with social anxiety disorder (SAD) can induce social fear behaviors in mice, suggesting a causal role of gut microbes in modulating behaviors relevant to SAD.

2 Jan 2024

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research delves into the complex roles of neutrophils in inflammatory bowel disease (IBD), exploring their diverse functions and interactions with the gut microbiota and emphasizing the need for targeted therapies based on these insights.

27 Dec 2023

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

Chemokine News and Research

Further Reading

Natural killer cells lead the charge in cancer treatment innovation

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

Never-before-documented genetic disorder causes rare lung disease

Immune cells in overdrive: Study finds unbalanced response worsens lung infections

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

Small-molecule A485 mobilizes white blood cells on demand

Study reveals new mechanisms involved in the development of inflammatory cardiovascular diseases

COVID-19-associated blood plasma inflammatory factors do not affect blood-brain barrier, study shows

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Unlocking the anti-inflammatory secrets of bergamot byproducts

Immune dysregulation in long COVID patients uncovered in new study

Study: Respiratory syncytial virus directly infects nerve cells and causes inflammation

Gut microbiota linked to social anxiety behaviors

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Autopsy study provides new insights into yellow fever's impact on the heart

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Key role of ion and water influx in T cell migration uncovered

Carrot juice boosts immune response, cuts inflammation, new study reveals

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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