Chromosome Y News and Research

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The Y chromosome is one of the two sex chromosomes in humans (the other is the X chromosome). The sex chromosomes form one of the 23 pairs of human chromosomes in each cell. The Y chromosome spans about 58 million base pairs (the building blocks of DNA) and represents almost 2 percent of the total DNA in cells.

Each person normally has one pair of sex chromosomes in each cell. The Y chromosome is present in males, who have one X and one Y chromosome, while females have two X chromosomes.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. The Y chromosome likely contains between 70 and 200 genes. Because only males have the Y chromosome, the genes on this chromosome tend to be involved in male sex determination and development. Sex is determined by the SRY gene, which is responsible for the development of a fetus into a male. Other genes on the Y chromosome are important for male fertility.

Many genes are unique to the X or Y chromosome, but genes in an area known as the pseudoautosomal region are present on both chromosomes. As a result, men and women each have two functional copies of these genes. Many genes in the pseudoautosomal region are essential for normal development.

Genes on the Y chromosome are among the estimated 20,000 to 25,000 total genes in the human genome.
DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

Gene variants can increase risk of schizophrenia, shows study

Gene variants can increase risk of schizophrenia, shows study

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Variations in genome’s 'dark matter' region can make patients susceptible to inflammatory diseases

Variations in genome’s 'dark matter' region can make patients susceptible to inflammatory diseases

Researchers use “gene drive” technology to eliminate malaria mosquitoes in lab experiments

Researchers use “gene drive” technology to eliminate malaria mosquitoes in lab experiments

Scientists uncover important functions of a special protein during cell division

Scientists uncover important functions of a special protein during cell division

Woman's genetic make-up may play a role in weight gain from birth control

Woman's genetic make-up may play a role in weight gain from birth control

Study: Recombination is crucial for proper segregation of chromosomes into germs cells

Study: Recombination is crucial for proper segregation of chromosomes into germs cells

Harmful effects of BPA can be reversed by administering coenzyme Q10

Harmful effects of BPA can be reversed by administering coenzyme Q10

Study provides more insight into the initiation and progression of human cancers

Study provides more insight into the initiation and progression of human cancers

COVID-19 infection risk and outcomes explained by the cell receptor genetic variability

COVID-19 infection risk and outcomes explained by the cell receptor genetic variability

New therapeutic possibilities for treating intellectual disability in Down syndrome

New therapeutic possibilities for treating intellectual disability in Down syndrome

Researchers describe an underlying biological basis for mylagic encephalomyelitis/chronic fatigue syndrome

Researchers describe an underlying biological basis for mylagic encephalomyelitis/chronic fatigue syndrome

New study indicates novel therapies for Duchenne muscular dystrophy

New study indicates novel therapies for Duchenne muscular dystrophy

Bayreuth researchers discover natural protective mechanism against cancer

Bayreuth researchers discover natural protective mechanism against cancer

Researchers discover physiological mechanisms underlying pediatric B-ALL

Researchers discover physiological mechanisms underlying pediatric B-ALL

ACE2 genetic variants may influence coronavirus disease progression

ACE2 genetic variants may influence coronavirus disease progression

Mutated ATP1B gene a risk factor for Parkinson’s

Mutated ATP1B gene a risk factor for Parkinson’s

New mathematical model can help explain why so many pregnancies and IVF attempts fail

New mathematical model can help explain why so many pregnancies and IVF attempts fail

Why do so many pregnancies and in vitro fertilization attempts fail?

Why do so many pregnancies and in vitro fertilization attempts fail?