Chromosome Y News and Research

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The Y chromosome is one of the two sex chromosomes in humans (the other is the X chromosome). The sex chromosomes form one of the 23 pairs of human chromosomes in each cell. The Y chromosome spans about 58 million base pairs (the building blocks of DNA) and represents almost 2 percent of the total DNA in cells.

Each person normally has one pair of sex chromosomes in each cell. The Y chromosome is present in males, who have one X and one Y chromosome, while females have two X chromosomes.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. The Y chromosome likely contains between 70 and 200 genes. Because only males have the Y chromosome, the genes on this chromosome tend to be involved in male sex determination and development. Sex is determined by the SRY gene, which is responsible for the development of a fetus into a male. Other genes on the Y chromosome are important for male fertility.

Many genes are unique to the X or Y chromosome, but genes in an area known as the pseudoautosomal region are present on both chromosomes. As a result, men and women each have two functional copies of these genes. Many genes in the pseudoautosomal region are essential for normal development.

Genes on the Y chromosome are among the estimated 20,000 to 25,000 total genes in the human genome.
Researchers identify new risk gene for Parkinson's disease

Researchers identify new risk gene for Parkinson's disease

Modifiable risk factors could play important role in Alzheimer's disease, study finds

Modifiable risk factors could play important role in Alzheimer's disease, study finds

OGT delivers translocation and partial tandem duplication detection with updates to SureSeq NGS portfolio

OGT delivers translocation and partial tandem duplication detection with updates to SureSeq NGS portfolio

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

New study offers clues to why autism is more common in boys than in girls

New study offers clues to why autism is more common in boys than in girls

Key protein in sperm production could aid male infertility treatments

Key protein in sperm production could aid male infertility treatments

3D chromatin landscapes in T cell acute lymphoblastic leukemia important beyond DNA code changes

3D chromatin landscapes in T cell acute lymphoblastic leukemia important beyond DNA code changes

Study identifies ancestral fragments of DNA associated with hereditary prostate cancer

Study identifies ancestral fragments of DNA associated with hereditary prostate cancer

Changes in 3D genetic structure equally important as DNA code mutations in childhood leukemia

Changes in 3D genetic structure equally important as DNA code mutations in childhood leukemia

Researchers elucidate new mechanism for controlling DNA methylation in cells

Researchers elucidate new mechanism for controlling DNA methylation in cells

Recognizing CDKL5 Deficiency Disorder

Recognizing CDKL5 Deficiency Disorder

Researchers probe how specific genes can impact early brain development

Researchers probe how specific genes can impact early brain development

Abnormal retinal gene function underlying vision loss in dogs

Abnormal retinal gene function underlying vision loss in dogs

Why do women live longer?

Why do women live longer?

Observation of telomerase activity at a single-molecule level using 'optical tweezers'

Observation of telomerase activity at a single-molecule level using 'optical tweezers'

Novel technique helps trace individual chromosomes during embryonic development

Novel technique helps trace individual chromosomes during embryonic development

New discovery may be useful for developing novel cancer treatments

New discovery may be useful for developing novel cancer treatments

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Chromosomal imbalance in cancer cells can either promote or inhibit metastasis

Chromosomal imbalance in cancer cells can either promote or inhibit metastasis

DNA topological problems may cause lymphoma, study shows

DNA topological problems may cause lymphoma, study shows