Crohn's Disease News and Research

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Crohn’s disease is a chronic inflammatory disease of the bowel affecting at least 115,000 people in the UK. The condition usually develops in teenagers and young adults, but can be diagnosed at any age and is equally common in men and women.

The condition can affect any part of the digestive tract between the mouth and the anus, although inflammation in the last section of the small bowel (ileum) or the first part of the large bowel (colon) is most common.

Crohn's disease is a ‘relapsing and remitting’ condition characterized by symptom-free periods followed by episodes of “flare-ups,” during which symptoms such as diarrhoea, abdominal pain, fever and fatigue may become particularly bothersome.

Long term, severe inflammation can damage sections of the digestive system, resulting in additional complications, such as a tear in the wall of the anus (fissure), narrowing of the intestine (stricture) or the formation of an abnormal connection between the bowel and another body part such as the bladder, vagina or skin (fistula). Such problems usually require surgical treatment to correct. Crohn's disease also increases the risk of developing bowel cancer.

The exact cause of Crohn's disease is not clear but experts believe a combination of factors may be at work including genetics, immune responses to certain bacteria or viruses and lifestyle factors such as diet or smoking status.
UAB expert provides in-depth understanding of food-borne illnesses

UAB expert provides in-depth understanding of food-borne illnesses

Study findings provide new insight into inflammatory bowel disease

Study findings provide new insight into inflammatory bowel disease

Antifungals and probiotics could play critical role in potential new therapeutic approaches for IBD

Antifungals and probiotics could play critical role in potential new therapeutic approaches for IBD

Study uncovers millions of previously unknown genes in human microbiome

Study uncovers millions of previously unknown genes in human microbiome

Crohn's & Colitis Foundation and Oxford University Press partner to publish Inflammatory Bowels Diseases journal

Crohn's & Colitis Foundation and Oxford University Press partner to publish Inflammatory Bowels Diseases journal

MSC transplantation can be safe, effective approach to treat Crohn's disease-related fistula

MSC transplantation can be safe, effective approach to treat Crohn's disease-related fistula

Study provides new insights into biologic networks involved in IBD

Study provides new insights into biologic networks involved in IBD

Researchers show that separate septic and aseptic procedure rooms is unnecessary

Researchers show that separate septic and aseptic procedure rooms is unnecessary

Blood test using infrared spectroscopy could provide cheaper, quicker alternative for colitis screening

Blood test using infrared spectroscopy could provide cheaper, quicker alternative for colitis screening

Exclusive enteral nutrition may be effective treatment for children with Crohn's disease

Exclusive enteral nutrition may be effective treatment for children with Crohn's disease

Home visits help new parents overcome tough histories, raise healthy children

Home visits help new parents overcome tough histories, raise healthy children

Drug-like molecule appears to interfere with inflammatory response in variety of diseases

Drug-like molecule appears to interfere with inflammatory response in variety of diseases

Biomedical scientist receives $1.83 million NIH grant for inflammatory bowel disease research

Biomedical scientist receives $1.83 million NIH grant for inflammatory bowel disease research

Research identifies crucial insights into early T-cell development

Research identifies crucial insights into early T-cell development

Researchers win $1.4 million federal grant to study new treatment approaches for intestinal inflammation

Researchers win $1.4 million federal grant to study new treatment approaches for intestinal inflammation

Sheffield scientists discover that simple arthritis drug could help treat blood cancer sufferers

Sheffield scientists discover that simple arthritis drug could help treat blood cancer sufferers

Mango intake exerts beneficial effects in progression and severity of IBD

Mango intake exerts beneficial effects in progression and severity of IBD

Researchers highlight role of micro-guests in pathologic processes

Researchers highlight role of micro-guests in pathologic processes

Researchers unravel how acidic conditions favor protein misfolding in deadly diseases

Researchers unravel how acidic conditions favor protein misfolding in deadly diseases

Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients

Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients