Cyanosis News and Research

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Cyanosis refers to abnormal blue discoloration of the skin and mucous membranes. The term is derived from the Greek word kuaneos meaning dark blue.

Understanding and addressing neurodevelopmental challenges in congenital heart disease

More than a decade of new knowledge about neurodevelopmental risk in people with congenital heart disease has changed the thinking about who is most at risk and the factors that impact neurological development, learning, emotions and behaviors, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

22 Feb 2024

Neonates exposed to SARS-CoV-2 in utero at higher risk of respiratory distress, study finds

Researchers found that neonates born to mothers with SARS-CoV-2 infection face an increased risk of respiratory distress, potentially due to an inflammatory response triggered by prenatal exposure.

29 Jan 2024

The effect of moderate intensity exercise in pregnant women with cardiovascular disease

Researchers assess the effect of moderate-intensity exercise in pregnant women with cardiovascular disease.

19 Apr 2023

SARS-CoV-2 transmission from infected owner to pet rats

SARS-CoV-2 Omicron transmission from a symptomatically infected individual to two domestic rats.

19 Oct 2022

The role of SARS-CoV-2 in COVID-19-associated chilblains

A recent study published in the British Journal of Dermatology evaluated COVID-19-associated chilblains.

23 Aug 2022

What impact has SARS-CoV-2 variant B.1.1.519 had on Mexico City?

The current study reports the effective reproduction number of B.1.1.519 and presents its geographical origin based on phylogenetic analysis.

20 Sep 2021

Gout drug may improve heart function in individuals with congenital heart disease

A drug used to treat gout, probenecid, may improve heart function in individuals with a particular heart defect, according to results from a small pilot study run by a University of Cincinnati researcher.

27 Aug 2020

Old letters provide insight into Spanish flu pandemic horror

An archive of letters written by those who survived the Spanish flu pandemic at the start of the last century shows what it was actually like to live during that time. The Spanish flu pandemic killed over 250,000 people in Britain alone and worldwide it wiped out a population of over 100 million.

23 Sep 2018

Study sheds new light on underlying genetic causes of congenital heart disease

Approximately one in every 100 babies is born with congenital heart disease (CHD), and CHD remains the leading cause of mortality from birth defects.

9 Oct 2017

Children with single-ventricle disease have higher rates of brain abnormalities at each stage of surgery

As children with single-ventricle disease, a complex and severe heart defect, undergo a series of three reconstructive surgeries, pediatric researchers have detected higher rates of brain abnormalities at each stage.

4 May 2017

Lung cancer surgery patients at higher risk of developing venous thromboembolism

New evidence suggests that lung cancer surgery patients are at higher risk of developing venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE), than previously thought, with elevated risks of complications or death. When thromboemboli occur, they may be asymptomatic or attributed to post-surgical pain or complications, and may reflect both the lung cancer itself as well as compromised lung function after surgery.

29 Apr 2015

Research opens door to new direction of PAH treatment

The development of new, more effective vasodilators to treat pulmonary arterial hypertension has been hampered because of their systemic toxicity and adverse side effects. An international team of investigators seeking to surmount these problems and increase drug efficacy have determined that a vascular homing peptide can selectively target hypertensive pulmonary arteries to boost the pulmonary but not systemic effects of vasodilators. Importantly for potential clinical use, this peptide retains its activity when given sublingually. The results using a rat model of PAH are published in the American Journal of Pathology.

8 Jan 2014

IUSL awarded patent for method for changing perception of skin tone

How someone perceives color is determined by how the item they are looking at scatters and emits light. In August, three City College of New York physicists affiliated with the Institute for Ultrafast Spectroscopy and Lasers (IUSL) were awarded a patent for a method for changing perception of skin tone by applying quantum and optical principles to cosmetic preparations.

6 Nov 2013

Positive new data from Genzyme’s eliglustat tartrate Phase 3 studies on Gaucher disease type 1

Genzyme, a Sanofi company, today announced positive new data from the Phase 3 ENGAGE and ENCORE studies of eliglustat tartrate, its investigational oral therapy for Gaucher disease type 1.

15 Feb 2013

AMAG seeks FDA sNDA approval for Feraheme Injection

AMAG Pharmaceuticals, Inc. today announced that it has submitted a supplemental new drug application (sNDA) to the United States Food and Drug Administration (FDA) for Feraheme (ferumoxytol) Injection for Intravenous (IV) use.

25 Dec 2012

AMAG presents new data from two ferumoxytol phase III trials on IDA at ASH annual meeting

AMAG Pharmaceuticals, Inc. today announced that new data from two pivotal phase III clinical trials were presented at the American Society of Hematology's (ASH) annual meeting in Atlanta, Georgia.

11 Dec 2012

AMAG receives Swiss marketing authorization for ferumoxytol to treat iron deficiency anemia

AMAG Pharmaceuticals, Inc. today announced that the Swiss Agency for Therapeutic Products (Swissmedic) has granted marketing authorization in Switzerland for ferumoxytol, an intravenous (IV) iron therapy to treat iron deficiency anemia (IDA) in adult patients with chronic kidney disease.

6 Sep 2012

Cyanosis News and Research

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