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Bioinspired method detects and detoxifies harmful chemicals in single step

Many industrial and agriculture processes use chemicals that can be harmful for workers and the ecosystems where they accumulate.

12 Aug 2019

Innovative technology could help treat cancer more selectively and effectively

Treating cancer more selectively and more effectively - this could be achieved with an innovative technology developed by teams of researchers at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and the Ludwig-Maximilians-Universität München.

9 Aug 2019

Innovative technology could treat cancer more selectively and effectively

9 Aug 2019

Antioxidant precursor molecule could improve dopamine levels in Parkinson's patients

N-acetylcysteine (NAC) is a naturally occurring molecule that replenishes one of the body's antioxidants and now shows potential benefit as part of a standard course of treatment for patients with Parkinson's disease, according to a study published in the journal, Clinical Pharmacology & Therapeutics.

16 Jul 2019

Ludwig Cancer Research study discovers new cellular oxygen sensor

A Ludwig Cancer Research study led by Peter Ratcliffe and colleagues has discovered a previously overlooked oxygen sensor in animal cells that functions very much like one used by plants.

5 Jul 2019

Researchers identify genes linked with survival in children with biliary atresia

Scientists at Cincinnati Children's Hospital Medical Center have identified an expression pattern of 14 genes at the time of diagnosis that predicts two year, transplant-free survival in children with biliary atresia – the most common diagnosis leading to liver transplants in children.

19 Jun 2019

Research reveals immunomodulatory role of ent-kaurane diterpenoids toward NK cells

As early responders in the surveillance of malignant cells, natural killer cells play a significant role in the control of transformed cells at the tumor initiation stage through direct cytolysis. For this reason, NK cell-based immunotherapy is a potential therapeutic strategy for tumor sufferers.

31 May 2019

Researchers synthesize new polysulfide donor that has high anti-inflammatory effect

Researchers from Japan have developed a new polysulfide donor: a chemical compound composed of chains of sulfur atoms that can artificially increase reactive sulfur species (chemically reactive molecules containing sulfur) in cells and tissues.

4 Apr 2019

Study uncovers new chemical reaction key to cataract formation

Researchers working to understand the biochemistry of cataract formation have made a surprising finding: A protein that was long believed to be inert actually has an important chemical function that protects the lens of the eye from cataract formation.

28 Nov 2018

Researchers succeed in building protein nanotubes from tiny scaffolds

Researchers at Tokyo Institute of Technology have succeeded in constructing protein nanotubes from tiny scaffolds made by cross-linking of engineered protein crystals.

14 Nov 2018

Researchers uncover how common pain reliever causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins at an amino acid called cysteine.

11 Oct 2018

How Does Amyloid Formation Impact Neurodegenerative Disease?

An interview with Dr Rosie Staniforth discussing her research into amyloid formation and its impact on neurodegenerative diseases.

From Postnova Analytics 11 Oct 2018

Breakthrough fluorine discovery may impact how pharmaceutical companies develop new drugs

A groundbreaking discovery by chemists at The University of Texas at San Antonio will have a significant impact on how pharmaceutical companies develop new drug treatments.

6 Sep 2018

UTA scientists map function of enzymes to provide keys for developing new drugs

UTA biochemists are mapping the function of specific enzymes which may facilitate development of new drugs to fight bacterial infection, cancer and potentially neurodegenerative diseases like autism, Down syndrome, Parkinson's disease and Alzheimer's.

30 Aug 2018

Ubiquigent launches REDOXprofiler for rapid identification of REDOX cycling compounds

Ubiquigent Limited, a company specializing in providing ubiquitin cell-signalling system drug discovery services, research tools and novel targeted chemistry, announced today that it has launched REDOXprofiler.

24 Aug 2018

A simple pill for meth addicts on the cards

Researchers from Australia's Curtin University have developed a simple pill that could be used to treat methamphetamine addicts. It would soon be tried in a clinical trial to prove its efficacy and utility said the researchers.

18 Jul 2018

New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

5 Jun 2018

Taurine deficiency in sperm linked to male infertility

Sperm are highly specialized cells adapted to achieve a single goal: fertilize an egg. Along the road to fertilization sperm must embark on a lengthy journey to the female oviduct, avoiding several fatal stresses that occur when they pass through different physiological environments.

11 May 2018

New studies use proteomics to shed light on pathogenic mechanisms

Recent studies in the journal Molecular & Cellular Proteomics have shed light on pathogenic mechanisms of the sexually-transmitted parasite Trichomonas vaginalis and the HIV-associated opportunistic lung fungus Aspergillus.

11 May 2018