Cysteine News and Research

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Insilico Medicine announces launch of intelligently-formulated nutraceuticals in Europe

Insilico Medicine, Inc, a big data analytics company applying latest advances in deep learning to drug discovery, biomarker development, and aging research today announced that the line of nutraceuticals developed in collaboration with Life Extension will be available across Europe.

5 Apr 2017

New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

In an article published recently in Plos One, researchers from INRS-Institut Armand-Frappier Research Centre reported a strategy that could lead to the discovery of new cationic antimicrobial peptides (CAMPs) with greatly enhanced antimicrobial properties.

5 Apr 2017

Researchers characterize ‘gold fingers’ using ion mobility mass spectrometry

Drugs containing gold have been used for centuries to treat conditions like rheumatoid arthritis. In addition, they might be effective against cancer and HIV.

28 Mar 2017

Researchers identify mechanisms involved in acid pump

Researchers at Aarhus University, Denmark, have succeeded in identifying the mechanisms involved in what is known as the acid pump, which at the cellular level pumps acid into the stomach - in some cases leading to gastric ulcers and gastroesophageal reflux disease.

7 Mar 2017

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease.

3 Jan 2017

Japanese researchers discover that 2-aminobutyric acid can effectively raise antioxidant levels

A Japanese research team has become the first in the world to discover that 2-aminobutyric acid (2-AB) is closely involved in the metabolic regulation of the antioxidant glutathione, and that it can effectively raise levels of glutathione in the body when ingested.

15 Dec 2016

Antioxidant levels could be boosted with newly-found amino acid function

14 Dec 2016

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

A new technique offers better sensitivity and accuracy in detecting an essential biomarker of cancer and inflammatory diseases.

7 Dec 2016

Blocking key nutrient uptake may be effective way of treating triple negative breast cancer

Cancer rewires the metabolism of tumor cells, converting them into lean, mean, replicating machines.

21 Nov 2016

Boosting levels of detoxification compound may help prevent metabolic decline linked to aging

Researchers at Oregon State University have found that a specific detoxification compound, glutathione, helps resist the toxic stresses of everyday life - but its levels decline with age and this sets the stage for a wide range of age-related health problems.

24 Oct 2016

Optical and PET/CT activity-based probes could help in non-invasive imaging of atherosclerotic plaques

Researchers at Stanford University have demonstrated for the first time the use of a dual optical and PET/CT activity-based probe to detect atherosclerotic plaques. The study is published in the October issue of the Journal of Nuclear Medicine.

20 Oct 2016

NAC improves effectiveness of adoptive cell therapy for treating melanoma

A collaborative team of investigators at the Medical University of South Carolina and Loyola University have demonstrated for the first time that culturing T cells in N-acetyl cysteine (NAC) before they are infused as immunotherapy improves effectiveness and outcomes in a preclinical model of melanoma. These findings were reported in the October 15, 2016 issue of Cancer Research.

17 Oct 2016

Study finds decreased cysteine/cystine ratio could serve as accurate redox biomarker for epilepsy

Approximately 2.9 million people in the United States suffer from epilepsy, according to the CDC.

5 Oct 2016

CIRM approves $5.2 million for research on life-long treatment for rare childhood disease

Cystinosis is a rare disease that usually strikes children before they are two years old and can lead to end stage kidney failure before their tenth birthday.

22 Sep 2016

TSRI scientists shed light on molecular workings of MS drug

A study by scientists at The Scripps Research Institute has helped to de-mystify the molecular workings of the multiple sclerosis (MS) drug Tecfidera. The drug is the most widely prescribed pill-based therapy for MS, but its biological mechanism remains mysterious.

21 Sep 2016

Scientists create stable boron carrier for targeted radiation-based tumour therapies

Targeted radiation-based therapies for treating cancerous tumours such as 'boron neutron capture therapy' (BNCT), rely on the efficient and effective delivery of the capture agent (in this case, boron) to the tumour.

11 Aug 2016

Researchers uncover novel virulence strategies employed by Leishmania parasite

Professor Albert Descoteaux of INRS-Institut Armand-Frappier Research Centre and his team have discovered novel virulence strategies employed by the Leishmania parasite.

29 Jul 2016

Researchers discover pathway linking oxidative stress and cysteine in Huntington's disease

Researchers at Johns Hopkins Medicine report they have identified a biochemical pathway linking oxidative stress and the amino acid cysteine in Huntington's disease.

27 Jul 2016

New technology could help deliver treatments for brain injuries

A new study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute describes a technology that could lead to new therapeutics for traumatic brain injuries. The discovery, published today in Nature Communications, provides a means of homing drugs or nanoparticles to injured areas of the brain.

29 Jun 2016

Natural molecule NAC could benefit patients with Parkinson's disease

The natural molecule, n-acetylcysteine (NAC), with strong antioxidant effects, shows potential benefit as part of the management for patients with Parkinson's disease, according to a study published today in the journal PLOS ONE.

17 Jun 2016