Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

The currently available evidence on viral-induced parkinsonism

The currently available evidence on viral-induced parkinsonism

New study provides comparison of replicating and non-replicating vaccines against SARS-CoV-2

New study provides comparison of replicating and non-replicating vaccines against SARS-CoV-2

Doctors discover genetic and viral causes of adenoid hypertrophy in kids

Doctors discover genetic and viral causes of adenoid hypertrophy in kids

SARS-CoV-2 infection in mothers does not have a significant teratogenic effect

SARS-CoV-2 infection in mothers does not have a significant teratogenic effect

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

Study confirms link between Epstein-Barr virus and multiple sclerosis

Study confirms link between Epstein-Barr virus and multiple sclerosis

Scientists explore immune memory of common cold coronaviruses before the SARS-CoV-2 pandemic era

Scientists explore immune memory of common cold coronaviruses before the SARS-CoV-2 pandemic era

Maternal antibodies may play a key role in protecting infants from congenital HCMV infections

Maternal antibodies may play a key role in protecting infants from congenital HCMV infections

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

The successful transplantation of genetically engineered pig hearts into recently deceased humans

The successful transplantation of genetically engineered pig hearts into recently deceased humans

Beyond COVID-19: the potential future applications of mRNA vaccines

Beyond COVID-19: the potential future applications of mRNA vaccines

Stress accelerates aging of the immune system

Stress accelerates aging of the immune system

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

Topical ocular administration of progesterone could be viable treatment for retinitis pigmentosa

Topical ocular administration of progesterone could be viable treatment for retinitis pigmentosa

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

Study explores neurologic complications in pediatric COVID-19 cases

Study explores neurologic complications in pediatric COVID-19 cases

Mice live longer with nasal gene therapy

Mice live longer with nasal gene therapy

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Scientists examine the impact of herpesviruses on (pre)diabetes

Scientists examine the impact of herpesviruses on (pre)diabetes

Exploring simultaneous and sequential COVID-19 vaccine candidate

Exploring simultaneous and sequential COVID-19 vaccine candidate

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