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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Evolutionarily ancient enzyme-repair system used to identify type of DNA damage responsible for the onset of skin-tumor development

In a finding that broadens our insight into the cause of certain kinds of UV-induced skin cancer, researchers at Erasmus University Medical Center (Rotterdam, The Netherlands) have employed an evolutionarily ancient enzyme-repair system to identify the principal type of DNA damage responsible for the onset of skin-tumor development.

26 Jan 2005

New method of delivery of gene therapy may lead to safer treatment for cancer

The Lankenau Institute for Medical Research (LIMR) announced that in collaboration with the Massachusetts Institute of Technology (MIT) they have performed preclinical proof-of- principle studies showing how nanotechnology can be used to enhance gene therapy for cancer.

25 Jan 2005

New technique can greatly facilitate the development of vaccines against infectious diseases such as smallpox, malaria and tuberculosis

Because the new technique can synthesize a large number of proteins very quickly, it has potential to accelerate vaccine development, particularly crucial in the fight against bioterrorism.

25 Jan 2005

Modern humans have sloppy gene control mechanisms which can make us susceptible to diseases

Our evolutionary ancestors’ lack of choice in the mating game has left modern humans exposed to disease, according to new research published in the journal PLOS Biology today.

25 Jan 2005

New blood tests to soon replace painful bone marrow biopsies for leukemia and lymphoma patients

Quest Diagnostics Incorporated announced today that The University of Texas M. D. Anderson Cancer Center in Houston has granted the company exclusive use of five proprietary blood testing methods, which, once available in the form of laboratory diagnostic tests, may eliminate the need for painful and expensive bone marrow and other tissue extractions.

24 Jan 2005

Priming embryonic stem cells to fulfill their promise

Bioengineering researchers at the University of California, San Diego have invented a process to help turn embryonic stem cells into the types of specialized cells being sought as possible treatments for dozens of human diseases and health conditions.

24 Jan 2005

High blood pressure risk in African-Americans linked to genetics

National health records have shown that African-Americans are more prone to high blood pressure than Caucasians, but pinning down the roots of that difference has proven elusive. Now, researchers at the Stanford University School of Medicine have narrowed down the search for genes that contribute to this difference in disease risk.

24 Jan 2005

NIH begins Phase 1 clinical trial of HIV vaccine candidate

GenVec announced today that the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), has begun the second Phase 1 clinical trial in healthy adult volunteers of an HIV vaccine candidate jointly developed by the Dale and Betty Bumpers Vaccine Research Center (VRC), a part of NIAID, and GenVec.

19 Jan 2005

Elsevier to launch journal devoted to nanomedicine

Elsevier has announced plans to launch a peer-reviewed journal devoted to nanomedicine - the emerging science of using molecular machines to treat human disease. Nanomedicine: Nanotechnology, Biology, and Medicine, the official publication of the American Academy of Nanomedicine, will be published quarterly, with the first issue to appear in March 2005.

18 Jan 2005

Single gene mutation as the cause of around one in 25 cases of Parkinson’s disease worldwide

The studies suggest that the mutation, in a recently discovered gene called LRRK2, causes around 5% of inherited Parkinson’s cases and around 2% of isolated cases. Screening for the new mutation is likely to become a component of genetic testing for Parkinson’s disease in the near future.

17 Jan 2005

Study provides insight into strategies for telomere-based molecular cancer therapeutics

A new study published in the January issue of Cancer Cell provides exciting new information about how to boost the effectiveness of a promising cancer treatment that targets telomeres in an attempt to interfere with the ability of a cancer cell to continuously divide.

17 Jan 2005

Researchers attack cervical cancer

As more and more promising results of clinical trials on vaccination against human papillomaviruses are published, the more likely it becomes that an HPV vaccine will be the first licensed immunization against a sexually transmitted disease.

17 Jan 2005

Prototype needle-free drug and vaccine delivery device

Dr Mark Kendall, an Oxford University Research Lecturer in Engineering and Associate Director of the PowderJect Centre for Gene and Drug Delivery Research, has been named one of the top younger engineers in the country for his research into needle-free vaccine delivery technology.

17 Jan 2005

Scientists are a step closer to developing drug targets to treat fungal meningitis

Scientists are a step closer to developing drug targets to treat fungal meningitis -- the infection linked to at least three deaths on Vancouver Island -- thanks to the sequencing of two Cryptococcus genomes by an international team that included researchers at the University of British Columbia and the BC Cancer Agency's Michael Smith Genome Sciences Centre in Vancouver.

17 Jan 2005

Human Genome Project may have made traditional race-based measurements of human differences obsolete

New and sophisticated methods for studying the relationship between human genetic differences, the environment, health and behavior, all made possible by the completion of the Human Genome Project, have made traditional race-based measurements of human differences obsolete

17 Jan 2005

GenoMed files patent application on two genes linked to common cancers

GenoMed announced today that it has filed a patent application on two genes linked to common cancers. These are the first new disease genes the company has filed on since its multiple patent applications about ACE, a "master" disease gene.

17 Jan 2005

Scientists discover that microRNAs regulate thousands of human genes

For many years, DNA and proteins have been viewed as the real movers and shakers in genomic studies, with RNA seen as little more than a messenger that shuttles information between the two.

16 Jan 2005

Missing sequence of the human Y chromosome may contain genes controlling stature and tumor development

Scientists have reported in the journal Genome Research that they have successfully cloned and characterized a previously intractable DNA sequence: a 554-kilobase-pair genomic segment near the centromere of the human Y chromosome. This sequence contains eight putatively active genes that could be implicated in sex-associated height differences and gonadal tumor development.

16 Jan 2005

Using models to understand malaria

Malaria is one of the world's major killers. More than 500 million people live in epidemic regions and some 2 million - mostly children - die each year. And each year, drug resistance increases in the malarial parasite, Plasmodium falciparum, and the search for new treatments becomes more desperate.

12 Jan 2005

Plant research may help understand cancer

The development of cancer is a complex process with a number of different causes. The root problem is loss of control in the cell division process. A fundamental biological process, cell division can be studied in many organisms.

10 Jan 2005

DNA News and Research

Further Reading

Evolutionarily ancient enzyme-repair system used to identify type of DNA damage responsible for the onset of skin-tumor development

New method of delivery of gene therapy may lead to safer treatment for cancer

New technique can greatly facilitate the development of vaccines against infectious diseases such as smallpox, malaria and tuberculosis

Modern humans have sloppy gene control mechanisms which can make us susceptible to diseases

New blood tests to soon replace painful bone marrow biopsies for leukemia and lymphoma patients

Priming embryonic stem cells to fulfill their promise

High blood pressure risk in African-Americans linked to genetics

NIH begins Phase 1 clinical trial of HIV vaccine candidate

Elsevier to launch journal devoted to nanomedicine

Single gene mutation as the cause of around one in 25 cases of Parkinson’s disease worldwide

Study provides insight into strategies for telomere-based molecular cancer therapeutics

Researchers attack cervical cancer

Prototype needle-free drug and vaccine delivery device

Scientists are a step closer to developing drug targets to treat fungal meningitis

Human Genome Project may have made traditional race-based measurements of human differences obsolete

GenoMed files patent application on two genes linked to common cancers

Scientists discover that microRNAs regulate thousands of human genes

Missing sequence of the human Y chromosome may contain genes controlling stature and tumor development

Using models to understand malaria

Plant research may help understand cancer

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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