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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Ichor Medical Systems issued key patent

Ichor Medical Systems today announced that it has been issued a patent that protects vital elements of the company's technology.

25 Aug 2005

New insight into how sunlight affects DNA

Chemists at Ohio State University have gained new insight into how sunlight affects DNA. And what they found overturns ideas about genetic mutation that originated decades ago.

24 Aug 2005

First human gene mutation that causes extreme farsightedness

Working with an Amish-Mennonite family tree, Johns Hopkins researchers at the Wilmer Eye Institute have discovered what appears to be the first human gene mutation that causes extreme farsightedness.

24 Aug 2005

First study to test the role of RNA chemical modifications on immunity

The investigators published their findings in the August issue of Immunity. "We think this study will open a new area of research in understanding how our immune systems protect us," says Weissman.

23 Aug 2005

State-of-the-art portable biosensing device based on micro and nanotechnologies

A state-of-the-art portable biosensing device based on micro- and nanotechnologies will empower doctors to rapidly and accurately forewarn patients of their genetic risk of developing diseases such as cancer.

23 Aug 2005

Novel mechanism, called recursive splicing reveals how cells process large genes

Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns).

22 Aug 2005

Global data exchange policy brings 100,000,000,000 letters of the genetic code

The world's three leading public repositories for DNA and RNA sequence information have reached 100 gigabases (100,000,000,000 bases; the 'letters' of the genetic code) of sequence.

22 Aug 2005

Discovery of a potential oncogene in ovarian cancer

Researchers at The University of Texas M. D. Anderson Cancer Center report they have discovered a potential oncogene in ovarian cancer, which is the leading cause of gynecological cancer death in U.S. women.

22 Aug 2005

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

The scientists found a gene mutation not previously known to be related to Fanconi anemia, and they say that BRIP1 is the first gene associated with the disease whose protein has a known function.

22 Aug 2005

Discovery of new gene FANCM sheds light on repair of damaged DNA

National Institute on Aging (NIA) researchers have discovered a new gene, FANCM, which sheds light on an important pathway involved in the repair of damaged DNA.

22 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Researchers have discovered a gene linked to age-related maculopathy

University of Pittsburgh researchers have discovered a gene linked to age-related maculopathy (ARM), the leading cause of untreatable blindness in the elderly. Their discovery suggests a simple test might be able to identify those at risk for what is commonly known as macular degeneration (AMD) and may lead to the development of more effective preventive strategies.

16 Aug 2005

Analytical tool to help detect cancer

Scientists have long used ultra-fine glass tubes known as capillaries to analyze the chemical makeup of substances. Called capillary electrophoresis, or CE, the method applies high voltage to the capillaries, and by measuring the rate that the various materials move through the capillaries, researchers are able to identify individual compounds.

16 Aug 2005

Genomes of Trypanosoma brucei and Trypanosoma cruzi sequenced

Oxford scientists have contributed to the genome sequencing of two parasites which cause major health problems in the developing world.

15 Aug 2005

MiRNA is opening up a whole new way of understanding carcinogenesis

Scientists mining vast, largely unexplored regions of the human genome have identified a small handful of mini-molecules that play a major role in the development of cancer and perhaps many other diseases.

15 Aug 2005

Activated Stat5 protein in prostate cancer can predict outcome, may help target treatment

Researchers from Lombardi Comprehensive Cancer Center at Georgetown University found that testing for an activated Stat5 protein in prostate tumor tissue effectively predicts which men have a form of prostate cancer that may become more aggressive and life threatening.

15 Aug 2005

DNA chip technology helps with discovery of new type 2 diabetes gene

In a new study appearing in the August 12 issue of the journal Cell, the investigators first identified genes that were altered in their level of expression in islets isolated from people with type 2 diabetes.

13 Aug 2005

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

A collaborative project between American and Chinese researchers developed a way to study the function of genes in mice and man by using a moveable genetic element from moths, according to a report in the journal Cell.

13 Aug 2005

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Scientists studying the structure and interaction of negatively charged lipids and DNA molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine.

13 Aug 2005

Pre-mRNA that codes for inflammatory protein identified

In a discovery that upends a longstanding tenet of human biology, University of Utah School of Medicine researchers have shown that a key process in gene regulation can occur in human platelets, unique cells that are unusual because they don't have a nucleus (anucleate).

11 Aug 2005

DNA News and Research

Further Reading

Ichor Medical Systems issued key patent

New insight into how sunlight affects DNA

First human gene mutation that causes extreme farsightedness

First study to test the role of RNA chemical modifications on immunity

State-of-the-art portable biosensing device based on micro and nanotechnologies

Novel mechanism, called recursive splicing reveals how cells process large genes

Global data exchange policy brings 100,000,000,000 letters of the genetic code

Discovery of a potential oncogene in ovarian cancer

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

Discovery of new gene FANCM sheds light on repair of damaged DNA

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Researchers have discovered a gene linked to age-related maculopathy

Analytical tool to help detect cancer

Genomes of Trypanosoma brucei and Trypanosoma cruzi sequenced

MiRNA is opening up a whole new way of understanding carcinogenesis

Activated Stat5 protein in prostate cancer can predict outcome, may help target treatment

DNA chip technology helps with discovery of new type 2 diabetes gene

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Pre-mRNA that codes for inflammatory protein identified

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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