DNA News and Research

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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

DNA repair by Brca2 prevents medulloblastoma

St. Jude investigators have gained some of the first major insights into how certain genes known to prevent cancer also guide the nervous system's normal development before birth and during infancy by repairing DNA damage.

23 Jun 2007

New understanding of modern pandemic infection

Human resistance to a retrovirus that infected chimpanzees and other nonhuman primates 4 million years ago ironically may be at least partially responsible for the susceptibility of humans to HIV infection today.

23 Jun 2007

New treatment slows the growth of colon and liver cancers

A. Navarro, a researcher at the School of Pharmacy of the University of Navarra, has developed a new treatment which slows the growth of colon and liver cancers.

23 Jun 2007

Adenovirus used to destroy cancer cells

With nearly $1 million in government funding, University of Rochester scientists are testing a new innovation in biotherapy by altering a common childhood respiratory virus, the adenovirus, to destroy cancer cells.

23 Jun 2007

RNA polymerase points to new targets for drug design

Researchers at UAB (University of Alabama at Birmingham) have new information on the structure of a key enzyme in bacteria that could lead to improved antibiotics and less antibiotic resistance.

23 Jun 2007

40 percent of parents willing to have their child's DNA stored in a government biobank

Genetic testing holds great promise for the future. Information generated by genetic testing may provide information that leads to new treatments for common diseases such as heart disease and diabetes.

23 Jun 2007

Entecavir can compromise HIV treatment

Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal, according to a new report in the New England Journal of Medicine.

23 Jun 2007

Whitehead scientist to study key mechanism in cell division

"Cell division is one of the most fundamental aspects of biology, the process that makes life," says Iain Cheeseman, PhD. "And it has an intrinsic beauty."

22 Jun 2007

Turn-ons and turn-offs for neurons

Our brain consists of billions of nerve cells enabling to learn, remember and reason.

20 Jun 2007

Master regulator of the stem cell state

For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types.

20 Jun 2007

Acquired DNA key to certain bacterial infection

Researchers announced this week the discovery of a mechanism by which Mycobacterium avium - a bacterium which can result in serious lung infections and is prevalent in emphysema and AIDS patients among others - infects tissue cells or macrophages and thus compromises the body's immunity.

19 Jun 2007

Faster, less expensive technique for mutating large, non-gene stretches of DNA

Genes account for only 2.5 percent of DNA in the human genetic blueprint, yet diseases can result not only from mutant genes, but from mutations of other DNA that controls genes.

19 Jun 2007

Alcohol may protect against rheumatoid arthritis

New data presented at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain, suggests that alcohol may protect against rheumatoid arthritis, with three units a week exhibiting protective effects and ten units a week being more protective still.

19 Jun 2007

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

Most known human genes in the genome map are still incompletely annotated, says Professor Alexandre Reymond, from the Centre for Integrative Genomics, University of Lausanne, Switzerland and the Department of Genetic Medicine, University of Geneva, Geneva, Switzerland.

19 Jun 2007

Otosclerosis gene identified

A gene responsible for the single most common cause of hearing loss among white adults, otosclerosis, has been identified for the first time, a scientist told the annual conference of the European Society of Human Genetics in Nice, France.

19 Jun 2007

Common DNA variations underlie susceptibility to fever after smallpox vaccination

Their finding is the first to link individual differences written into the genetic code with a vaccine-related complication, albeit a mild one.

19 Jun 2007

True nature of heterochromatin revealed

Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown.

19 Jun 2007

Scientists discover proteins in blood that accurately identify colon cancer and precancerous polyps

Initial studies of the proteins, CCSA-3 and CCSA-4, suggest they could be used to develop a blood test to identify at-risk individuals.

19 Jun 2007

New understanding of how the DNA helix replicates

A team of researchers led by University of Virginia Health System geneticists has uncovered a major secret in the mystery of how the DNA helix replicates itself time after time.

18 Jun 2007

Researchers use 'genomic pathway' to predict Parkinson's

A new Mayo Clinic study provides strong evidence that the joint effects of common DNA variations in several genes that encode proteins within a well-defined biological pathway largely explain why some persons get Parkinson's disease while others don't, and even predict with great accuracy at what age people might develop their first symptoms.

17 Jun 2007