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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Newly discovered gene could provide targets for diabetes therapies

The Juvenile Diabetes Research Foundation (JDRF) has announced that JDRF-funded researchers in Australia and the United Kingdom have identified a gene called Roquin that regulates the immune system and keeps harmful T cells in check.

1 Jun 2005

Interaction between cell and virus provides scientists valuable insights into the development of safe viral vectors for use in oncology

When infected by a virus, a cell uses specific defense mechanisms developed in the course of a long evolution. Thus, it can activate enzymes that disrupt or prevent replication of the viruses within the cell.

1 Jun 2005

Hybridon collaborates to develop immune modulatory (IMO) compounds for asthma and allergy

Hybridon today announced it had entered into research collaboration and license agreements with Novartis for the discovery, optimization, development and commercialization of Toll-like receptor 9 (TLR9) drug candidates targeting asthma and allergy based on Hybridon's proprietary immune modulatory oligonucleotide (IMO) technology platform.

1 Jun 2005

Exposure to pharmaceutical estrogen during fetal development can permanently "reprogram" tissue in a way that determines whether tumors will develop in adulthood

Researchers at The University of Texas M. D. Anderson Cancer Center may have uncovered the reason why some people who are genetically predisposed to hormone-dependent cancers develop the disease as an adult, while others who are similarly susceptible don't.

30 May 2005

New gene shows way for autoimmune disease

A new gene suspected to contribute to autoimmune diseases such as type 1 diabetes and lupus - a condition in which the body’s own immune system attacks organs such as the kidneys and skin - has been discovered by Australian National University (ANU) immunologists.

30 May 2005

New understanding of DNA repair processes may pave way to cancer treatments

A Burnham Institute study has found that a protein known for its role in gene regulation has another important function, that of initiating DNA repair. The study, published in the May 27th edition of Molecular Cell, points to new targets for treatment of cancer.

30 May 2005

Targeted Genetics issued patent related to adeno-associated virus (AAV) technology platform

Targeted Genetics Corporation has announced the issuance of another patent related to the Company's leading adeno-associated virus (AAV) technology platform. U.S. patent #6,897,045, titled "Adeno-Associated Virus Vectors," was issued to the University of Iowa Research Foundation and is exclusively licensed to Targeted Genetics.

30 May 2005

Bioniche Life Sciences granted European patent

Bioniche Life Sciences has announced that it has had another patent granted on its core technology: Mycobacterial Cell Wall-DNA Complex (MCC). The European Patent Organization (EPO) granted the patent: - "Composition and Method for Inducing Apoptosis in Prostate Cancer Cells" (EPO1165106)

30 May 2005

Technology for analyzing gene expression must be standardized

Technology for analyzing gene expression must be standardized among laboratories and across platforms around the world to support this age of human genome exploration, an Oregon Health & Science University researcher says.

29 May 2005

Why good medications are sometimes bad for the liver

The University of North Carolina at Chapel Hill is one of five clinical centers nationwide to receive funds from the National Institutes of Health to study why good medications are sometimes bad for the liver.

29 May 2005

'Brown fat cells' hold clues for possible obesity treatments

Joslin Diabetes Center scientists have discovered a group of genes that govern the genesis of calorie-burning fat cells. This discovery may lead to novel ways to treat obesity in humans.

26 May 2005

Protein, called "eed," crucial to the regulation of genes in embryonic stem cells

New research from University of North Carolina at Chapel Hill shows how a protein may be crucial to the regulation of genes in embryonic stem cells.

26 May 2005

Scientists show nuclear protein Ezh2 helps establish previously unknown signaling pathway in cells

Since 2001, scientists have wrestled with the discovery that there are fewer genes in humans than biological processes linked to those genes over the course of a human lifespan. One way to understand genetically coded events is by studying epigenetics, the regulation and heritability of genes at a cellular level due to molecular changes to the many proteins (called histones) that package DNA in a cell's nucleus.

23 May 2005

Gene keeps neural cells on correct developmental path

23 May 2005

Major step forward in stem cell research

Newcastle University (England) scientists have taken a major step forward in stem cell research, putting Britain in the vanguard of technology that could produce treatments for a range of conditions such as diabetes, Parkinson’s disease and spinal injuries.

23 May 2005

Gene keeps neural cells on correct developmental path

Embryonic stem cells with identical genomes grow into distinctive tissues, such as heart, bone, and brain. At one time, scientists believed the differences among cell types arose from various sets of genes switched on inside developing cells. Then, studies showed that adult neurons uniquely lack a protein that permanently turns off neuronal genes in the rest of the body's cells.

20 May 2005

Researchers generate patient-specific stem cells

Researchers have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury.

20 May 2005

Cetuximab (Erbitux) can battle cancer and prolong life in many patients with advanced colorectal cancer

"Even in people who have gone through six or more previous courses of chemotherapy, cetuximab, may fight the growth of cancer, giving patients additional months of life," says study presenter Heinz-Josef Lenz, M.D., associate professor of medicine at the Keck School of Medicine of the University of Southern California and USC/Norris Comprehensive Cancer Center.

20 May 2005

Bacteria in plaque may increase risk for heart attacks

Researchers have found evidence that the amount of bacteria in subgingival plaques, the deep plaques in periodontal pockets and around the teeth, may contribute to an individual's risk of a heart attack, according to two studies appearing the Journal of Periodontology.

20 May 2005

Bioniche granted additional patent for mycobacterial cell wall technology

Bioniche Life Sciences Inc., a research-based, technology-driven human and animal health biopharmaceutical company, today announced that it has had a new patent issued by the United States Patent and Trademark Office (USPTO) on its core mycobacterial cell wall technology.

18 May 2005

DNA News and Research

Further Reading

Newly discovered gene could provide targets for diabetes therapies

Interaction between cell and virus provides scientists valuable insights into the development of safe viral vectors for use in oncology

Hybridon collaborates to develop immune modulatory (IMO) compounds for asthma and allergy

Exposure to pharmaceutical estrogen during fetal development can permanently "reprogram" tissue in a way that determines whether tumors will develop in adulthood

New gene shows way for autoimmune disease

New understanding of DNA repair processes may pave way to cancer treatments

Targeted Genetics issued patent related to adeno-associated virus (AAV) technology platform

Bioniche Life Sciences granted European patent

Technology for analyzing gene expression must be standardized

Why good medications are sometimes bad for the liver

'Brown fat cells' hold clues for possible obesity treatments

Protein, called "eed," crucial to the regulation of genes in embryonic stem cells

Scientists show nuclear protein Ezh2 helps establish previously unknown signaling pathway in cells

Gene keeps neural cells on correct developmental path

Major step forward in stem cell research

Gene keeps neural cells on correct developmental path

Researchers generate patient-specific stem cells

Cetuximab (Erbitux) can battle cancer and prolong life in many patients with advanced colorectal cancer

Bacteria in plaque may increase risk for heart attacks

Bioniche granted additional patent for mycobacterial cell wall technology

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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