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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Exploring how gene variants affect brain cells in children with severe epilepsy

Epilepsy is a brain disorder that causes recurring seizures.

16 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

Study reveals human gut plasmid with biomarker potential

A component of the human intestinal flora that has been little studied to date is the focus of a new study.

16 Apr 2024

Genetically engineering skin bacteria to fight cancer

While studying a type of bacteria that lives on the healthy skin of every human being, researchers from Stanford Medicine and a colleague may have stumbled on a powerful new way to fight cancer.

15 Apr 2024

Arabica coffee's genetic legacy unveiled

The key to growing coffee plants that can better resist climate change in the decades to come may lie in the ancient past.

15 Apr 2024

Study reveals how aberrant epigenetic regulation contributes to aggressive pediatric brain tumors

A new study conducted by researchers at Tampere University and Tampere University Hospital revealed how aberrant epigenetic regulation contributes to the development of atypical teratoid/rhabdoid (AT/RT) tumors, which are aggressive brain tumors that mainly affect young children.

15 Apr 2024

Tiny DNA circles are key drivers of cancer formation, study suggests

Tiny circles of DNA that defy the accepted laws of genetics are key drivers of cancer formation, according to an international study led by researchers at Stanford Medicine.

15 Apr 2024

Bio-Rad announces collaboration agreement with oncocyte to commercialize transplant monitoring with droplet digital PCR

Collaboration Aims to Provide Researchers Cutting-Edge Tools to Enable Transformational Monitoring of Key Biomarkers in Solid Tissue Transplants.

From Bio-Rad Laboratories 15 Apr 2024

Understanding the role of genetic variants in male infertility

Approximately one in seven couples face difficulties conceiving a child naturally. Half of these cases are due to male infertility – either caused by the complete absence or low number of mature sperm.

13 Apr 2024

Hospital sinks fuel antibiotic-resistant bacteria spread

A new study published today in the American Journal of Infection Control reports the infection prevention steps taken to control a months-long multispecies outbreak of carbapenemase-producing Enterobacterales that occurred in a pediatric ward at the Toho University Omori Medical Center in Tokyo in 2017.

12 Apr 2024

Unveiling the key role of RNA modification in HIV-1 survival and replication

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

12 Apr 2024

Study reveals how DNA gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Nanopore sequencing unveils novel telomere length patterns

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Link between aldehydes and premature aging revealed

A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging.

12 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

ChatGPT could be an effective tool to help reduce vaccine hesitancy

New research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) suggests that the free-to-use, widely accessible ChatGPT could be an effective tool to help reduce vaccine hesitancy among the general public, as well as providing helpful advice on sexually transmitted infections (STIs) in conjunction with sexual health clinics, by improving knowledge and access to care.

10 Apr 2024

New lab assay could make diagnosis and treatment of lung cancer easier

A new lab assay developed by researchers at Fred Hutch Cancer Center could make diagnosis and treatment of small-cell lung cancer and non-small cell lung cancer easier.

10 Apr 2024

Unraveling the complex web of rectal infections and the microbiome in MSM

Study delves into the relationships between various sexually transmitted infections, including Neisseria gonorrhoeae, Chlamydia trachomatis, Torquetenovirus, and high-risk HPV, and their effects on the anorectal microbiome among men who have sex with men (MSM), unveiling complex interactions that may influence infection outcomes and treatment strategies.

10 Apr 2024

LMU researchers shed light on DNA repair mechanisms in Cockayne syndrome

Cockayne syndrome is a severe autosomal recessive disorder caused by defective DNA repair mechanisms.

10 Apr 2024

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

10 Apr 2024