DNA Purification News and Research

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The value of whole-exome sequencing as a first-tier genetic test in the diagnosis of skin disorders

The genetic etiology by whole-exome sequencing (WES).

23 Aug 2023

New sensor chip detects disease pathogens with 10x sensitivity

Texas A&M AgriLife Research scientists and collaborators at Iowa State University have developed a sensor chip that can detect many disease pathogens with 10 times the sensitivity of currently available methods.

26 Jun 2023

The importance of accurate pipetting in biomedical laboratory work

In this interview, Stephanie Stursberg, Group Product Manager for pipetting platforms at INTEGRA Biosciences, talks to NewsMedical about the importance of accurate and efficient pipetting in biomedical laboratory work.

From INTEGRA Biosciences 2 Nov 2022

Lysis Buffer for High Yield Enzymatic Shearing

Porvair Sciences reports how its Chromatrap® Lysis buffer for enzymatic shearing provides users with a complete lysis buffer for the disruption of nuclear cell membranes with a milder detergent than that required for mechanical fragmentation.

From Chromatrap® - Porvair Sciences Ltd 3 Sep 2021

High recovery of top-quality purified RNA

Porvair Sciences has launched new kits for rapid extraction of total RNA from a wide range of biological samples. These proprietary kits enable extraction of up to 1000 µg of application-ready pure RNA in as little as 10 minutes.

From Chromatrap® - Porvair Sciences Ltd 14 Apr 2021

New study unravels complete sequence of DNA repair mechanism

Every living organism has DNA, and every living organism engages in DNA replication, the process by which DNA makes an exact copy of itself during cell division. While it's a tried-and-true process, problems can arise.

25 Jan 2021

Naturally selected mutations of SARS-CoV-2 easily duplicated in vitro

In a recent and timely paper, currently available on the bioRxiv preprint server, researchers from Israel and France demonstrated how in vitro evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD) follows contagious mutation spread – but can also generate an efficient infection inhibitor.

10 Jan 2021

High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

Now, an intriguing recent study appeared on the bioRxiv * preprint server describes the use of in vitro evolution to elicit affinity maturation of the viral receptor-binding domain (RBD) of the spike protein to bind the host cell angiotensin-converting enzyme 2 (ACE2) with greater affinity.

7 Jan 2021

Advances in Virus Epigenetics

Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood.

From Chromatrap® - Porvair Sciences Ltd 25 Aug 2020

Coastal Genomics automates DNA purification process using 3D printing – accelerating cancer research, prenatal screening and numerous other fields by partnering with Sculpteo

Coastal Genomics, experts in life sciences automation, selected Sculpteo, a leader in online 3D printing and digital manufacturing, to develop unique components for an automated DNA purification process.

18 Jun 2020

Lab Automation for Biome Research

News Medical Life Sciences discussed how lab automation can improve the efficiency of biome research with Tom Copeland, Sales and Marketing Coordinator of Hudson Robotics, at Pittcon 2020.

From Hudson Robotics 11 May 2020

BIA Separations selected to support AveXis’ gene therapy pipeline

BIA Separations, a leading biochromatography development and manufacturing company, today announced it is collaborating with AveXis, a Novartis company, to enhance the commercial purification process for its gene therapy pipeline, beginning with Zolgensma (onasemnogene abeparvovec-xioi), the first U.S. Food and Drug Administration-approved gene therapy indicated for the treatment of pediatric patients with spinal muscular atrophy (SMA) who are less than two years of age.

22 Jul 2019

Disrupting ChIP Assay Technology with New Advancements

The Chromatrap ChIP technology is a bead-free method of performing ChIP. The potential of the technology emerged from our capabilities in manufacturing porous plastic filters for the filtration and separation of biological materials.

From Chromatrap® - Porvair Sciences Ltd 27 Jun 2019

High Throughput Nucleic Acid Purification Simplified

Labs demand purity and flexibility for high throughput nucleic acid purification, while needing to complete difficult downstream analysis, for example NGS.

From Promega Corporation 9 Apr 2019

Isolating Bacterial Pathogen DNA from Food Samples

Isolating bacterial pathogen DNA is important and often seen as QA ensure that the food manufactured or the ingredients used do not contain food-borne bacteria.

From Promega Corporation 5 Mar 2019

Easy and inexpensive test could one day help guide epilepsy treatment

An easy and inexpensive test for the HLA-B*15:02 allele could one day allow clinicians to quickly identify which epilepsy patients are at risk of carbamazepine hypersensitivity, according to study results presented by Gita V. Soraya at ILAE's 2018 Asian & Oceanian Epilepsy Congress in Bali.

4 Sep 2018