DNA Replication News and Research

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DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.
Molecular insight into oxygen sensing mechanism

Molecular insight into oxygen sensing mechanism

DNA synthesis in the 3’ and 5’ direction possible using new template-directed method

DNA synthesis in the 3’ and 5’ direction possible using new template-directed method

Parental methylated histones not transferred to daughter DNA

Parental methylated histones not transferred to daughter DNA

Orc1 mutations may explain pathology in manifestations of Meier-Gorlin syndrome

Orc1 mutations may explain pathology in manifestations of Meier-Gorlin syndrome

Microbiologists reveal how T. brucei’s key proteins organize to replicate its mtDNA

Microbiologists reveal how T. brucei’s key proteins organize to replicate its mtDNA

Study reveals new information about origin of tumors

Study reveals new information about origin of tumors

Researchers identify mechanism by which Zds1 protein regulates key function in mitosis

Researchers identify mechanism by which Zds1 protein regulates key function in mitosis

KLF15 molecule inhibits action of estrogen in the endometrium

KLF15 molecule inhibits action of estrogen in the endometrium

TopBP1 protein prevents early brain cells from DNA damage

TopBP1 protein prevents early brain cells from DNA damage

Cyclin D1 oncogene may promote chromosomal instability

Cyclin D1 oncogene may promote chromosomal instability

Cancer Genomics now available online

Cancer Genomics now available online

Sofie to receive U.S. patent for novel PET probes

Sofie to receive U.S. patent for novel PET probes

Shorter Chk1 protein neutralizes longer sibling to potentially benefit cancer patients

Shorter Chk1 protein neutralizes longer sibling to potentially benefit cancer patients

Scientists discover how DNA mismatch repair proteins work

Scientists discover how DNA mismatch repair proteins work

New substance can replace nucleoside thymidine in DNA biosynthesis

New substance can replace nucleoside thymidine in DNA biosynthesis

Researchers shed light on inner workings of endocycle

Researchers shed light on inner workings of endocycle

HSV1 drugs could slow progression of Alzheimer's disease

HSV1 drugs could slow progression of Alzheimer's disease

Researchers identify unusual genomic architecture linked with very severe forms of disease

Researchers identify unusual genomic architecture linked with very severe forms of disease

Cornell researchers learn how helicase enzyme works to unzip two strands of DNA

Cornell researchers learn how helicase enzyme works to unzip two strands of DNA

Caffeine in sunscreens may protect from skin cancer: Study

Caffeine in sunscreens may protect from skin cancer: Study