Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
MPD Foundation funds research for incurable blood disorders

MPD Foundation funds research for incurable blood disorders

Whole genome analysis of the protein kinases from Dictyostelium

Whole genome analysis of the protein kinases from Dictyostelium

Researchers identify potential targets for more effective analgesic drugs with potentially fewer side effects

Researchers identify potential targets for more effective analgesic drugs with potentially fewer side effects

Promising new targets for Alzheimer's drug therapies

Promising new targets for Alzheimer's drug therapies

Proteomics yields new drug targets for treating cardiogenic shock

Proteomics yields new drug targets for treating cardiogenic shock

Drug discoveries may be aided by formation of drug-target database

Drug discoveries may be aided by formation of drug-target database

Removing a gene involved in repairing damaged DNA causes metabolic syndrome

Removing a gene involved in repairing damaged DNA causes metabolic syndrome

New system for analyzing how drugs bind to proteins

New system for analyzing how drugs bind to proteins

Chink in cancer's armor

Chink in cancer's armor

Molecular Devices introduces a high-speed, laser-scanning, confocal imager

Molecular Devices introduces a high-speed, laser-scanning, confocal imager

Alternative method to produce heparin

Alternative method to produce heparin

Novel compound stops brain cell degeneration in Alzheimer's disease

Novel compound stops brain cell degeneration in Alzheimer's disease

Galapagos and Cancer Research Technology announce new anti-cancer drug discovery collaboration

Galapagos and Cancer Research Technology announce new anti-cancer drug discovery collaboration

Vioxx may still be the best option for treating some forms of arthritis

Vioxx may still be the best option for treating some forms of arthritis

Drug discovery companies turn to low-cost Asian countries to evade stringent regulations

Drug discovery companies turn to low-cost Asian countries to evade stringent regulations

Prospect of personalized medicine places new demands on the evaluation of new medicines

Prospect of personalized medicine places new demands on the evaluation of new medicines

MorphoSys signs agreement with Merck

MorphoSys signs agreement with Merck

New anti-clotting treatment

New anti-clotting treatment

Australian researchers determine structure of JAK2 kinase, huge implications for development of new cancer drugs

Australian researchers determine structure of JAK2 kinase, huge implications for development of new cancer drugs

Wellcome Trust awards £8.1 million to tackle tropical diseases

Wellcome Trust awards £8.1 million to tackle tropical diseases