Ductal Carcinoma News and Research

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Weight gain after breast cancer is a greater problem than previously thought

New study findings suggest that weight gain after breast cancer is a greater problem than previously thought.

25 Feb 2020

Measuring 'stickiness' of cancer cells could improve prognostic evaluation of tumors

A team of researchers led by the University of California San Diego has created a device that measures how "sticky" cancer cells are, which could improve prognostic evaluation of patient tumors. The device is built with a microfluidic chamber that sorts cells by their physical ability to adhere to their environment.

3 Feb 2020

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

Radiation therapy alone found to be cost-effective for treatment of DCIS

Ductal carcinoma in-situ (DCIS) accounts for one-fifth of breast cancer cases in the United States, according to the American Cancer Society.

11 Dec 2019

Shorter course of high-dose radiation treatment shows promise in breast cancer patients

A shorter course of higher-dose radiation treatment to part of the breast is showing promise in women with early-stage breast cancer who undergo breast conserving surgery, says a study led by Hamilton researchers.

6 Dec 2019

Women treated for early-stage breast cancer may develop invasive breast cancer

New research in the November 2019 issue of JNCCN—Journal of the National Comprehensive Cancer Network examines the implications of invasive breast cancer after breast-conserving treatment for ductal carcinoma in situ (aka DCIS, a form of non-invasive breast cancer) and which factors could impact overall survival.

25 Nov 2019

New research could help better understand progress of breast cancer

New research at Case Western Reserve University could help better determine which patients diagnosed with the pre-malignant breast cancer commonly as stage 0 are likely to progress to invasive breast cancer and therefore might benefit from additional therapy over and above surgery alone.

29 Oct 2019

Older women with DCIS gain no benefit from sentinel lymph node biopsy

Older women with a very early, non-invasive breast cancer known as ductal carcinoma in situ (DCIS) gain no long-term benefit from undergoing a sentinel lymph node biopsy to see if the cancer has spread, new research by the Yale School of Public Health has found.

24 Oct 2019

Cell adhesion protein promotes metastasis in breast cancer, study reveals

Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis.

From Johns Hopkins Medicine 11 Sep 2019

AI system could help better detect and diagnose breast cancer

UCLA researchers have developed an artificial intelligence system that could help pathologists read biopsies more accurately and to better detect and diagnose breast cancer.

12 Aug 2019

Partial breast irradiation effective alternative for treatment of low-risk breast cancer patients

Partial breast irradiation produces similar long-term survival rates and risk for recurrence compared with whole breast irradiation for many women with low-risk, early stage breast cancer, according to new clinical data from a national clinical trial involving researchers from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 May 2019

Six factors associated with invasive breast cancer recurrence after DCIS diagnosis

Six factors were associated with invasive recurrence of breast cancer after a diagnosis of ductal carcinoma in situ (DCIS), according to data from a meta-analysis.

25 Apr 2019

Radiation therapy can lower risk of breast cancer recurrence in patients with ‘good risk’ DCIS

A subset of patients with low-risk breast cancer is highly unlikely to see cancer return following breast conservation surgery but can lower that risk even further with radiation therapy, finds a new long-term clinical trial report.

30 Oct 2018

Breast Cancer as a Dynamic Disease

An interview with Dr. Andrew Ewald, discussing the influence of the myoepithelium on breast cancer growth and the importance of studying metastasis.

19 Oct 2018

Study identifies molecular switch that controls fate of milk-producing breast cells

A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

15 Oct 2018

Twice-a-year MRI more effective than mammograms for women with genetic breast cancer risk

Getting magnetic resonance imaging scans twice a year instead of one annual mammogram is far more effective at detecting early breast cancers in young women with a high-risk genetic profile than mammograms alone, according to a research team based at the University of Chicago Medicine and the University of Washington, Seattle.

14 Sep 2018

All MSP participants with invasive breast cancer can undergo more sparing surgical treatment

Participants in the German mammography screening program (MSP) who have invasive breast cancer—including interval cancers—can on the whole undergo more sparing surgical treatment compared with non-participants.

31 Aug 2018

Lumpectomy plus radiation associated with reduced risk of breast cancer death, study finds

Lumpectomy plus radiation was associated with a small clinical benefit in reduced risk of breast cancer death compared with lumpectomy or mastectomy alone in women with ductal carcinoma in situ, a noninvasive early form of breast cancer.

13 Aug 2018

Removing the cancer label - overhaul in cancer classification proposed

Australian researchers have asked for changes in the way doctors tend to label low risk cancerous conditions as “cancer” leading to over treatment. Certain diagnoses such as localised prostate cancer or “stage 0” breast cancers need to be looked at say the researchers at the University of Sydney and Bond University to prevent aggressive treatment where it is not needed.

12 Aug 2018

KU Cancer Center launches clinical trial to eliminate radiation therapy for HER2-positive breast cancer

Researchers at The University of Kansas Cancer Center have launched a clinical trial that eliminates radiation from the treatment protocol for an invasive type of breast cancer that accounts for one-fifth of all breast cancer patients.

30 Jun 2018