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Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Nanoparticles hold great promise for cancer diagnostics and therapies, but only to the extent that they can be selectively guided to tumors and cancer cells.

30 Mar 2015

DFG Senate approves establishment of one Clinical Research Unit, five Research Units

At its spring meeting in Bonn, the Senate of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) approved the establishment of one new Clinical Research Unit and five new Research Units.

30 Mar 2015

Mutations in hair keratins increase risk for dental defects, caries

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher Olivier Duverger, National Institutes of Health-National Institute of Neurological Disorders and Stroke, Bethesda, Md., USA, will present a study titled "Hair Keratins as Structural Organic Components of Mature Enamel: The Link Between Hair Disorders and Susceptibility to Dental Caries."

20 Mar 2015

Cardiac PET/CT imaging offers higher accuracy, better image quality than SPECT imaging

New heart imaging technology to diagnose coronary heart disease and other heart disorders is significantly more accurate, less expensive and safer than traditional methods, according to a new study by researchers from the Intermountain Medical Center Heart Institute in Salt Lake City.

17 Mar 2015

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

In 1953 Watson and Crick first published the discovery of the double helix structure of the DNA. They were able to visualize the DNA structure by means of X-Ray diffraction. Techniques, such as electron microscopy, allowed scientists to identify nucleosomes, the first and most basic level of chromosome organisation

13 Mar 2015

Researchers investigate effects of neuromodulatory medication on orofacial tissue

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher M.J. Al-Musawi, Newcastle University, Newcastle upon Tyne, UK, will present a study titled "In Vitro Effects of Topical Neuromodulatory Medication on Orofacial Tissue."

13 Mar 2015

When you eat is just as important as what you eat

If you're looking to improve your heart health by changing your diet, when you eat may be just as important as what you eat.

13 Mar 2015

TSRI researchers create picture of whole dynein-dynactin structure

A team led by scientists at The Scripps Research Institute has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.

12 Mar 2015

Andor Neo sCMOS camera is perfect partner for correlative microscopy

CD44 is recognised as an important cell surface receptor involved in the adhesion of circulating leukocytes to endothelium, a process that is critical for their trafficking in the vasculature. Now, a Japanese group of researchers using an ultra-sensitive Andor Neo sCMOS camera in their correlative microscopy set-up has demonstrated that microvilli projections around the cell surface mediate this adhesion.

From Andor Technology Ltd. 11 Mar 2015

Weak spots in ebola’s defenses: an interview with Dr. Andrew Ward

There are hundreds of other antibodies against Ebola that we are in the process of imaging using the electron microscope. We are looking for new sites of vulnerability as well as subtle differences in the way the known sites are attacked. In particular we are looking for antibodies that the virus is unlikely to escape from when it mutates.

11 Mar 2015

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Armed with a microscope capable of zooming in on organisms measured in billionths of a meter, scientists report they are the first to observe one of the tiny molecular machines that bacteria use to infect host cells. Findings appear in the Proceedings of the National Academy of Sciences.

10 Mar 2015

Nanobody Nano-85 holds promise for detection of noroviral RNA

Infection with highly contagious noroviruses, while not usually fatal, can lead to a slew of unpleasant symptoms such as excessive vomiting and diarrhea. Current treatment options are limited to rehydration of the patient. "Additionally, noroviruses come in a variety of constantly evolving strains.

9 Mar 2015

Scientists uncover how primary protein responsible for multidrug resistance reacts to therapeutic drugs

Cancer patients fear the possibility that one day their cells might start rendering many different chemotherapy regimens ineffective. This phenomenon, called multidrug resistance, leads to tumors that defy treatment.

5 Mar 2015

Research may help cancer centers provide better radiation therapy

Using complex computational algorithms based on repeated sampling, a University of Arkansas graduate student helped spearhead a project to develop a computer simulator that provides customized electron beam tunings for radiation therapy.

4 Mar 2015

TSRI researchers show how ABC transporters cause multidrug resistance

3 Mar 2015

Cherenkov Effect can help make radiation therapy safer, more effective for patients with cancer

The characteristic blue glow from a nuclear reactor is present in radiation therapy, too. Investigators from Dartmouth's Norris Cotton Cancer Center, led by Brian W. Pogue, PhD, and PhD candidates Adam K. Glaser and Rongxiao Zhang, published in Physics in Medicine and Biology how the complex parts of the blue light known as the Cherenkov Effect can be measured and used in dosimetry to make therapies safer and more effective.

26 Feb 2015

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

Christian Griesinger, director of the NMR-based Structural Biology department at the Max-Planck Institute for Biophysical Chemistry, talks about his research into neurodegenerative diseases using NMR to examine the dynamics of disordered proteins.

From Bruker BioSpin - NMR, EPR and Imaging 23 Feb 2015

EPSRC reveals new super-powerful electron microscope that can identify position of single atoms

A new super powerful electron microscope that can pinpoint the position of single atoms, and will help scientists push boundaries even further, in fields such as advanced materials, healthcare and power generation, will be unveiled today, Thursday February 19th, by the Engineering and Physical Sciences Research Council.

23 Feb 2015

From the scent of geranium to cough medicine; A self-assembling catalyst helps to construct complex biological scaffolds

With great elegance nature builds up complex structures from simple building blocks. A central class of compounds are terpenes. More than 8000 terpenes and about 30,000 of the related terpenoids are currently known. They are the key substances for many biological and pharmaceutical functions.

18 Feb 2015

NTU Singapore setting up new institute to find cures for human diseases

Nanyang Technological University is setting up a new institute to advance research in the life sciences, with a focus on ramping up Singapore's efforts in finding cures for human diseases.

16 Feb 2015

Electron News and Research

Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

DFG Senate approves establishment of one Clinical Research Unit, five Research Units

Mutations in hair keratins increase risk for dental defects, caries

Cardiac PET/CT imaging offers higher accuracy, better image quality than SPECT imaging

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

Researchers investigate effects of neuromodulatory medication on orofacial tissue

When you eat is just as important as what you eat

TSRI researchers create picture of whole dynein-dynactin structure

Andor Neo sCMOS camera is perfect partner for correlative microscopy

Weak spots in ebola’s defenses: an interview with Dr. Andrew Ward

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Nanobody Nano-85 holds promise for detection of noroviral RNA

Scientists uncover how primary protein responsible for multidrug resistance reacts to therapeutic drugs

Research may help cancer centers provide better radiation therapy

TSRI researchers show how ABC transporters cause multidrug resistance

Cherenkov Effect can help make radiation therapy safer, more effective for patients with cancer

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

EPSRC reveals new super-powerful electron microscope that can identify position of single atoms

From the scent of geranium to cough medicine; A self-assembling catalyst helps to construct complex biological scaffolds

NTU Singapore setting up new institute to find cures for human diseases

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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