Epigenomics News and Research

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New technique enhances understanding of chromatin organization

Researchers at the University of California San Diego Center for Epigenomics (C4E) have developed a new technique, called Droplet Hi-C, that allows scientists to rapidly determine chromatin organization, the arrangement of genetic material within cells.

18 Oct 2024

Computational tools unlock the secrets of the genome

In collaboration with the International Conference on Research in Computational Molecular Biology (RECOMB), Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.

13 Oct 2024

Unveiling the mechanism behind DNA organization in early embryos

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos.

16 Sep 2024

Study highlights benefits of exercise for both men and women

Females' and males' muscles differ in glucose and fatty acid handling – but regular physical activity quickly triggers similar beneficial metabolic changes in the muscles of both sexes, new research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9-13 September) has found.

16 Aug 2024

Advanced technology and AI used to diagnose rare diseases and birth abnormalities

Researchers at London Health Sciences Centre (LHSC) and Lawson Health Research Institute are using advanced technology and artificial intelligence (AI) to diagnose rare diseases and prenatal exposure-related birth abnormalities in two studies published today in American Journal of Human Genetics and Genetics in Medicine.

31 Jul 2024

Insilico Medicine's PandaOmics Box enhances drug discovery with advanced AI capabilities

The development of innovative medicines is an expensive, time-consuming and risky business. On average, it usually takes at least a decade and billions of dollars to bring a new drug from project initiation to approval.

25 Jul 2024

New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

With the advent of new omics technologies in recent years, there has been a deluge of complex, high-dimensional data on Alzheimer's disease (AD).

12 Jun 2024

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging.

24 May 2024

Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

A whole-organism molecular map of the temporal effects of endurance training in rats.

3 May 2024

Neuroscientists identify age-defying RNAs in the brain

Certain RNA molecules in the nerve cells in the brain last a life time without being renewed. Neuroscientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now demonstrated that this is the case together with researchers from Germany, Austria and the USA.

5 Apr 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

Researchers develop a cost-effective method to spatially characterize and map brain epigenomes

An estimated one in six people suffer from a brain disorder worldwide, according to the American Brain Foundation.

20 Mar 2024

AI and predictive medicine: Recent advances

The potential of deep learning (DL) in enhancing predictive modeling for omics data analysis.

4 Mar 2024

New standards for evaluating aging biomarkers unveiled

A new paper led by Harvard researchers has zeroed in on biomarkers of aging using omic data from population-based studies.

16 Feb 2024

Nutrigenomics paves the way for customized diets in lactose intolerance care

The current evidence on omics tools that allow for developing tailored nutrition strategies for individuals with lactose intolerance (LI).

24 Jan 2024

MAbID offers a deep dive into chromatin dynamics and gene regulation

Researchers from the group of Jop Kind developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease.

4 Dec 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Keck School of Medicine of USC to focus on Hispanic patients with NAFLD in multi-omics study

The Keck School of Medicine of USC has received funding from the National Institutes of Health as part of a five-year, $50.3 million "multi-omics" study of human health and disease involving six sites.

26 Sep 2023

Michigan researchers receive $26 million NIH grant to study environmental impacts on child health

Backed by a $26 million federal grant, researchers at three Michigan universities, a leading health care system, and a state agency will continue a long-term study of how exposure to environmental factors during pregnancy and early childhood can impact health for a lifetime.

1 Sep 2023