Fecal Transplant News and Research

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Researchers identify genes that may improve success of fecal microbe transplants

Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant.

13 Oct 2023

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

In a world-first clinical trial published in the journal Nature Medicine, a multi-center study from Lawson Health Research Institute, the Centre hospitalier de l'Université de Montréal and the Jewish General Hospital (JGH) has found fecal microbiota transplants (FMT) from healthy donors are safe and show promise in improving response to immunotherapy in patients with advanced melanoma.

7 Jul 2023

Fecal microbiota transplant: Effective solution for recurrent C. difficile infections

Researchers provide an overview of fecal microbiota transplantation in treating recurrent Clostridioides difficile infection.

27 Apr 2023

New treatment may help counteract food allergies and inflammatory diseases in future

Although many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal consequences.

22 Aug 2022

Gut virome may warn of a serious and often fatal disease in preterm infants

Immediately after birth, human infants begin to develop a complex, interwoven fabric of microbes in their gut.

26 Apr 2022

Exploring the vital connection between gut microbes, physical activity, and health

Our bowels accommodate billions of active microbes that affect the health, a fact that is arousing increasing interest also among athletes.

26 Mar 2022

Fiber-rich diet may help some melanoma patients to respond to immunotherapy

A diet rich in fiber may help some people being treated for melanoma respond to immunotherapy treatment by influencing the gut microbiome, according to a new study led by researchers at the Center for Cancer Research at the National Cancer Institute, part of the National Institutes of Health, and the University of Texas MD Anderson Cancer Center.

23 Dec 2021

UVA research sheds light on why fecal transplant can benefit patients with C. difficile infections

New research from the University of Virginia School of Medicine sheds light on why a fecal transplant can benefit patients with dangerous recurrent C. difficile infections – and suggests a way to improve patient outcomes.

14 Dec 2021

Maternal fecal transplant may help restore gut microbiota in newborns with diabetes risk

Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a Rutgers study.

20 Jul 2021

New research identifies a link between the gut microbiome and strokes

A recent study demonstrates the impact of diets that are high in choline and trimethylamine on increasing stroke severity and functional deficits.

21 Jun 2021

Plant-based diet appears to offer protection against hypertension and preeclampsia

A plant-based diet appears to afford significant protection to rats bred to become hypertensive on a high-salt diet, scientists report. When the rats become pregnant, the whole grain diet also protects the mothers and their offspring from deadly preeclampsia.

14 Jun 2021

Fecal transplant overcomes resistance to immunotherapy in melanoma patients

Researchers at UPMC Hillman Cancer Center and the National Cancer Institute demonstrate that changing the gut microbiome can transform patients with advanced melanoma who never responded to immunotherapy-;which has a failure rate of 40% for this type of cancer-;into patients who do.

5 Feb 2021

Mathematical model reveals the risk of SARS-CoV-2 infection after fecal microbiota transplantation

In their new paper available on the bioRxiv* preprint server, US researchers from the OpenBiome nonprofit organization used a mathematical model to simulate the usefulness of different testing strategies for fecal samples and showed that the probability of releasing a fecal microbiota donation with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is low when several important variables are taken into account.

28 Jun 2020

Common food additive alters gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

25 Jun 2020

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease.

9 Jun 2020

Study explores the growth rate effect of gut bacteria on break down of dietary fibers

It is known that approximately 80% of human immune system functions in the gastrointestinal tract. Gut bacteria and their metabolites play a fundamental role in the interaction between gut and other organs.

29 Apr 2020

Maternal consumption of low-calorie sweeteners alters metabolism, gut microbiota in offspring

Many people turn to artificial or so-called natural sweeteners to cut calories and lose weight. A new study led by Dr. Raylene Reimer, PhD, published in the high-impact journal Gut discovered that the consumption of low-calorie sweeteners while pregnant increased body fat in their offspring and disrupted their gut microbiota - the trillions of bacteria and other microorganisms that inhabit the intestinal tract and affect our health and risk of numerous diseases.

29 Jan 2020

Doctors report first death from fecal microbiota transplant

Details of an investigational study have emerged after a man died following a fecal microbiate transplant. The events prompted the FDA to set new safety guidelines for the practice.

31 Oct 2019

Gut microbiome altered by burn injury and influenced by fluid resuscitation, study shows

Major burns lead to changes in the gastrointestinal tract bacteria, and these alterations of the gut microbiome are influenced by resuscitation with intravenous (IV) fluids, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of theShockSociety. The journal is published in the Lippincott portfolio by Wolters Kluwer.

25 Oct 2019

Gut bacterial profile can predict gut damage following radiotherapy

Rather like a physical fingerprint, the gut microbial pattern can be used to identify certain vulnerabilities in patients who are undergoing radiation therapy for prostate or gynecologic cancer, predicting which of them are most likely to suffer damage to the intestine.

3 Oct 2019