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Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

A novel mouse model to test SARS-CoV-2 viral infection

In a recent study posted to the Research Square* preprint server, researchers developed a novel mouse model for testing infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

26 Apr 2022

Scientists win $2.85 million grant to use novel technology for studying babies with hydrocephalus

A five-year, $2.85 million grant to use novel technology to study babies with hydrocephalus has been awarded to a team of UTHealth Houston researchers by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

25 Apr 2022

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

For more than two decades, University of Alabama at Birmingham researcher Susan Bellis, Ph.D., has studied how the addition of sialic acid to various proteins increases cancer resistance and oncogenicity.

22 Apr 2022

New photo-responsive nanomedicine for light-controlled colorectal cancer therapy

A research team from Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has developed a photo-responsive nanomedicine for light-controlled colorectal cancer therapy.

21 Apr 2022

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Researchers demonstrated ocular tropism of SARS-CoV-2 through neuronal invasion in transgenic mice with hACE2 expression.

20 Apr 2022

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly.

18 Apr 2022

Researchers uncover a key regulator of pregnancy-associated heart growth

Northwestern Medicine scientists have uncovered a key regulator of pregnancy-associated heart growth, according to a recent study published in the Journal of Clinical Investigation.

18 Apr 2022

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

New aspergillosis infection model can help better observe the growth of fungus

A chip-based infection model developed by researchers in Jena, Germany, enables live microscopic observation of damage to lung tissue caused by the invasive fungal infection aspergillosis.

13 Apr 2022

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Researchers used cryogenic electron microscopy (cryo-EM) to determine the structure of the spike (S) protein of BA.2 sub-variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and compared them with previously determined S structures of Omicron's BA.1 sub-variant.

11 Apr 2022

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

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11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Researchers identify a potentially effective compound against COVID-19 against the SARS-CoV-2 PLpro.

10 Apr 2022

Cytoskeletal proteins work synergistically in the cell cortex to form intracellular networks

Investigators have discovered that two cytoskeletal proteins which were previously thought to function independently actually interact and form cytoskeletal networks within the cell surface, according to findings published in Proceedings of the National Academy of Sciences.

7 Apr 2022

Fluorescence News and Research

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

A novel mouse model to test SARS-CoV-2 viral infection

Scientists win $2.85 million grant to use novel technology for studying babies with hydrocephalus

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

New photo-responsive nanomedicine for light-controlled colorectal cancer therapy

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Researchers uncover a key regulator of pregnancy-associated heart growth

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

New aspergillosis infection model can help better observe the growth of fungus

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Cytoskeletal proteins work synergistically in the cell cortex to form intracellular networks

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Revolutionizing the fluorescence microscopy landscape with the all-in-one Microhub, Mica

Bruker introduces Ultima Investigator Plus — Multiphoton microscope for tissue imaging

New tissue-clearing method could speed the study of many disease-related biological processes

Fluorescence eBook

Michael Stryker

The past, present and future of automation and digitalization in the life sciences laboratory

Arxspan BioDrive: A Versatile Solution for Molecular Biology

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