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High-resolution atlas illustrates the development of human retina

What cell types are found in which human tissue, and where? Which genes are active in the individual cells, and which proteins are found there?

8 May 2023

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

In this study, the effects of a high-fat diet on the formation of bisretinoids in photoreceptor cells were explored. The results showed that mice on a high-fat diet had increased levels of bisretinoids and retinol-binding protein 4, which are associated with metabolic dysregulation.

8 May 2023

Intratumoral bacteria linked with natural purple photosynthetic bacteria show strong anticancer efficacy

Cancer remains one of the leading causes of death worldwide. Researchers are constantly looking for new therapies with improved anticancer activity, fewer side effects, and lower costs.

8 May 2023

Powerful two-photon microscopy for imaging fast biological processes

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution.

4 May 2023

New technique effectively identifies residual tumor tissue during breast-conserving surgery

A new technique designed to allow surgeons to identify and remove residual tumor tissue during breast-conserving surgery showed promising results in a multi-center trial led by investigators from the Mass General Cancer Center, a member of Mass General Brigham.

3 May 2023

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Cell membranes play a critical role by serving as containment units and separating the inner cellular space from the extracellular environment.

26 Apr 2023

Neutrophils found to play a key role in fibromyalgia pain

Targeting neutrophil activity and interactions with sensory neurons may be a potential approach for treating fibromyalgia pain.

25 Apr 2023

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

25 Apr 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

Researchers pioneer a new method for fast miRNA amplification and detection

In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes.

24 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

The Power of Solid-State Nuclear Magnetic Resonance in Biological Research

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Spectroscopy Award, Robert Tycko.

From Pittcon 20 Apr 2023

Researchers develop novel molecular nanocages for siRNA delivery

Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases.

19 Apr 2023

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

A team of researchers have developed an easy-to-use colorimetric assay for the detection of food contaminated with salmonella.

18 Apr 2023

Key memory receptor is localized to interneurons

A key receptor regulating memory formation has been localized to interneurons, according to a study with implications for drug development.

11 Apr 2023

Highly complementary, biologically relevant protein-protein interactions can evolve entirely by chance

Proteins are the key players for virtually all molecular processes within the cell. To fulfil their diverse functions, they have to interact with other proteins.

7 Apr 2023

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria.

7 Apr 2023

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

From CrestOptics 3 Apr 2023

Orbit Discovery and Evergreen Discovery collaborate to discover peptides for targeting radiopharmaceuticals

Evergreen Discovery (Evergreen), a leading radiopharmaceutical drug development company with a focus on the treatment and diagnosis of cancer.

From Orbit Discovery 3 Apr 2023

Groundbreaking technique offers a new way to gain detailed information about organic tissues

A groundbreaking technique developed by researchers affiliated with the USC Michelson Center for Convergent Bioscience presents a new way of gathering and organizing highly detailed information about organic tissues in record time.

31 Mar 2023

Fluorescence News and Research

High-resolution atlas illustrates the development of human retina

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

Intratumoral bacteria linked with natural purple photosynthetic bacteria show strong anticancer efficacy

Powerful two-photon microscopy for imaging fast biological processes

New technique effectively identifies residual tumor tissue during breast-conserving surgery

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Neutrophils found to play a key role in fibromyalgia pain

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Researchers pioneer a new method for fast miRNA amplification and detection

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

The Power of Solid-State Nuclear Magnetic Resonance in Biological Research

Researchers develop novel molecular nanocages for siRNA delivery

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

Key memory receptor is localized to interneurons

Highly complementary, biologically relevant protein-protein interactions can evolve entirely by chance

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

Orbit Discovery and Evergreen Discovery collaborate to discover peptides for targeting radiopharmaceuticals

Groundbreaking technique offers a new way to gain detailed information about organic tissues

Fluorescence eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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