Ganglion News and Research

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In anatomy, a ganglion (plural ''ganglia'') is a biological tissue mass, most commonly a mass of nerve cell bodies. Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to retinal ganglion cells.

Novel antibody shows promise for pain relief in peripheral nerves

Cell surface proteins play a crucial role in cell communication and in sensing changes in the extracellular environment.

9 Oct 2024

NYU Langone secures NIH award to explore eye imaging for early detection of Alzheimer's and Parkinson's

Researchers at NYU Langone Health were awarded $1.6 million from the National Institutes of Health (NIH) to investigate changes in the eye that may indicate early signs of Alzheimer's disease and Parkinson's disease.

2 Oct 2024

Study: Early brain wiring driven by spontaneous cellular activity

In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog -; four legs, fur, a tail, etc. -; a young child will eventually be able to identify dogs going forward.

16 Aug 2024

New brain targets for GLP1-based obesity drugs may reduce weight without nausea

Researchers identified distinct hindbrain GLP1R neurons driving satiety and aversion, offering new targets for effective, side-effect-free obesity treatments.

14 Jul 2024

Novel DNA aptamers of melanopsin developed to regulate circadian rhythm

DNA aptamers of melanopsin that regulate the clock hands of biological rhythms were developed by the Toyohashi University of Technology and the National Institute of Advanced Industrial Science and Technology (AIST) group.

12 Jul 2024

Innovative research sheds light on migraine mechanisms and potential therapies

New research describes for the first time how a spreading wave of disruption and the flow of fluid in the brain triggers headaches, detailing the connection between the neurological symptoms associated with aura and the migraine that follows.

4 Jul 2024

New signaling pathway identified in aural migraine headaches

The rapid influx of cerebral spinal fluid (CSF) and protein solutes released during cortical spreading depression (CSD) in the brain activates neurons to trigger aural migraine headaches, according to a new mouse study.

4 Jul 2024

Researchers characterize thalamic and cortical neurons that respond to stimulation of the ocular surface

Nerve fibers on the eye surface are involved in many relevant physiological processes, from detecting and transmitting external stimuli to maintaining the integrity of the cornea.

25 Jun 2024

Study identifies functional sex differences in specialized pain-producing nerve cells

Research suggests that males and females differ in their experience of pain, but up until now, no one knew why.

10 Jun 2024

Research reveals light's impact on metabolism beyond circadian rhythms

A recent Nature Metabolism review highlights how light exposure or deprivation affects metabolic activities like thermogenesis and glucose homeostasis through non-circadian pathways.

4 Jun 2024

Avian flu crosses species, infecting cats and cattle in Texas and Kansas

A study in the CDC's Emerging Infectious Disease Journal reports the spread of H5N1 avian influenza among cats and dairy cattle in Texas and Kansas, showing systemic illness in cattle and significant fatalities in cats exposed to the virus through infected milk.

1 May 2024

Proteasomes: Expanding roles beyond cellular waste management

The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts.

13 Apr 2024

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Ultra-processed foods linked to higher glaucoma risk, study warns

Study finds a significant relationship between the highest intake of ultra-processed foods, especially sweets, and an increased risk of developing glaucoma among Spanish university graduates, highlighting the importance of dietary quality for ocular health.

8 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

Although primary open-angle glaucoma (POAG) is the leading cause of blindness in people over the age of 55, there remains no cure for the disease and its biological mechanisms are not well understood.

16 Feb 2024

Johns Hopkins scientists unravel mystery of retinal cell communication

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical "vision" signals to the brain.

25 Jan 2024

IU researchers aim to develop a new therapy for glaucoma

Researchers at Indiana University School of Medicine are using a novel approach to hopefully develop a new therapy for glaucoma, a complex disease that eventually leads to blindness, thanks to a new five-year, $2 million R01 grant from the National Eye Institute.

8 Jan 2024

New research debunks color's influence on the human internal clock

Vision is a complex process. The visual perception of the environment is created by a combination of different wavelengths of light, which are decoded as colors and brightness in the brain.

22 Dec 2023