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Digital twins: Revolutionizing autoimmune disease treatment

Individual patients with autoimmune diseases can receive tailored medication by computationally treating their so-called digital twins with thousands of medications.

20 Mar 2024

Researchers develop a cost-effective method to spatially characterize and map brain epigenomes

An estimated one in six people suffer from a brain disorder worldwide, according to the American Brain Foundation.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

Study highlights causal associations between gut microbes and hypothyroidism

The association between the microbial community of the gut and hypothyroidism.

20 Mar 2024

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

19 Mar 2024

Severity of current SARS-CoV-2 variants is not linked to the number of mutations

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two most prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to previous variants.

19 Mar 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Study uncovers how APOBEC enzymes drive cancer mutations

A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.

18 Mar 2024

Study reveals the inner workings of gene mutations linked to ultra-rare syndrome

A team from the University of Ottawa's Faculty of Medicine has completed an exciting new study that reveals the inner workings of gene mutations that result in an ultra-rare syndrome with fewer than 100 reported cases since its first description in the early 1960s.

18 Mar 2024

Machine learning models to predict age from brain transcriptome changes

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, "Genome-wide transcriptome profiling and development of age prediction models in the human brain."

15 Mar 2024

Newly discovered adhesion GPCR mayo controls midgut development in Drosophila

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

15 Mar 2024

Rapid, easy-to-use diagnostic test could save more lives from melioidosis

Globally, more than half of patients die after infection with the neglected tropical disease, melioidosis, often before they are diagnosed.

13 Mar 2024

Atypical brain connections linked to ADHD symptoms

Researchers at the National Institutes of Health (NIH) have discovered that symptoms of attention-deficit/hyperactivity disorder (ADHD) are tied to atypical interactions between the brain's frontal cortex and information processing centers deep in the brain.

13 Mar 2024

Genome News and Research

Digital twins: Revolutionizing autoimmune disease treatment

Researchers develop a cost-effective method to spatially characterize and map brain epigenomes

Immune cell protein identified as potential target for rare liver cancer treatment

Study highlights causal associations between gut microbes and hypothyroidism

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Severity of current SARS-CoV-2 variants is not linked to the number of mutations

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study uncovers how APOBEC enzymes drive cancer mutations

Study reveals the inner workings of gene mutations linked to ultra-rare syndrome

Machine learning models to predict age from brain transcriptome changes

Newly discovered adhesion GPCR mayo controls midgut development in Drosophila

Rapid, easy-to-use diagnostic test could save more lives from melioidosis

Atypical brain connections linked to ADHD symptoms

Ricoh and ERS Genomics enter into CRISPR/Cas9 license agreement

Tracing Monkeypox virus: Leveraging ancient orangutan DNA to investigate the 1965 Rotterdam Zoo outbreak

Protein Kdm1a plays a crucial role in preserving neuronal identity, study shows

MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Groundbreaking study unveils sex-specific genetic influences on blood pressure

Study unravels FOXO1's influence on blood vessel development

Unveiling the molecular mechanism responsible for crossover interference during meiosis

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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