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MicroRNAs may increase cancer susceptibility

New evidence indicates that small pieces of noncoding genetic material known as microRNAs (miRNAs) might influence cancer susceptibility.

24 May 2007

Researchers find alteration in gene associated with uterine cancer

Researchers at the Translational Genomics Research Institute (TGen) today announced the discovery of previously unrecognized alterations in a gene called FGFR2 in a subset of endometrial cancers, the most common gynecologic cancer in the United States.

24 May 2007

Tool will revolutionise functional genomic studies in clostridia

The genome of the organism that produces the world's most lethal toxin has been revealed.

24 May 2007

Status of malaria in the world today

In an editorial in this week's JAMA: The Journal of the American Medical Association, Gianna Zuccotti, M.D., Contributing Editor, and Catherine D. DeAngelis, M.D., M.P.H., Editor in Chief, JAMA, comment on the status of malaria in the world today.

24 May 2007

Scientists evolve new proteins from scratch

Nature, through the trial and error of evolution, has discovered a vast diversity of life from what can only presumed to have been a primordial pool of building blocks.

24 May 2007

MIT researchers uncover surprising difference in gene regulation in mouse and human liver cells

Scientists often study mice as a model for human biology and disease, because their basic biological processes are assumed to be essentially the same as those of humans.

22 May 2007

Decoding gene expression in cancer tumors using noninvasive imaging

By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine has developed tools that may some day allow physicians to view a CT image of a cancer tumor and discern its genetic activity.

22 May 2007

Genes add up risk of autoimmune disease

Geneticists have identified a link between the number of copies of a specific gene an individual has and their susceptibility to autoimmune diseases like lupus.

22 May 2007

New computational system identifies viruses and bacteria

Now that the genome sequences of hundreds of bacteria and viruses are known, we can design tests that will rapidly detect the presence of these species based solely on their DNA.

18 May 2007

First draft of the genome sequence of Aedes aegypti mosquito

Developing new strategies to prevent and control yellow fever and dengue fever has become more possible with the completion of the first draft of the genome sequence of Aedes aegypti mosquito by scientists led by Vishvanath Nene at The Institute for Genomic Research (TIGR) and David Severson at the University of Notre Dame.

18 May 2007

Scientists convert the sequence of proteins into music

UCLA molecular biologists have turned protein sequences into original compositions of classical music.

17 May 2007

Study of unexplained respiratory infections leads researchers to new virus

An ongoing effort to identify the microorganisms that make us sick has discovered a new virus potentially linked to unexplained respiratory infections.

17 May 2007

Yin Yang 1 regulates early B cell development

A new paper in the May 15th issue of Genes & Development reveals how a protein called Yin Yang 1 regulates early B cell development.

17 May 2007

Dealing with emerging diseases

The outbreak of severe acute respiratory syndrome (SARS) in 2002 was a loud wake-up call for researchers studying infectious diseases.

16 May 2007

Study finds large number of new proteins implicated in Huntington's disease

Researchers from four organizations have identified more than 200 new proteins that bind to normal and mutant forms of the protein that causes Huntington's disease (HD).

11 May 2007

Opossum DNA provides new insight into natural selection

Study of the DNA of a South American marsupial called the opossum has revealed that a gene's location influences whether or not it is likely to gather changes that could lead to disease.

10 May 2007

Researchers map genome for mite-borne typhus

Researches at Uppsala University, in collaboration with a Korean research team, have mapped and analyzed the genome for mite-borne typhus.

10 May 2007

FluForecast trial predicted high human H5N1 mortality in Indonesia

When H5N1 was thought to be quiescent in 2006, in a prospective open trial, FluForecast, a software program which measures virus gene proteins, predicted high human mortality H5N1 outbreaks to come.

10 May 2007

Structural variation in the human genome

A major new effort to uncover the medium- and large-scale genetic differences between humans may soon reveal DNA sequences that contribute to a wide range of diseases, according to a paper by Howard Hughes Medical Institute investigator Evan Eichler and 17 colleagues published in the May 10, 2007, Nature.

10 May 2007

Bipolar disorder - the clue may be in the genes

The first scan of the entire human genetic code has revealed that developing bipolar disorder may to some extent depend on the combined effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself.

9 May 2007