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Study causes big shift in how we think about p53 gene

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate mutations, which ultimately may lead to cancer.

27 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

Found! - mutant viruses that laid NSW low with gastro

New mutant viruses responsible for gastroenteritis outbreaks in New South Wales in recent times have been identified by research published in Emerging Infectious Diseases, a journal of the US Centers for Disease Control.

27 Jun 2005

PNNL ScalaBLAST may be used to process complex genomic sequences

A new computational tool developed at the Department of Energy's Pacific Northwest National Laboratory is speeding up our understanding of the machinery of life - bringing us one step closer to curing diseases, finding safer ways to clean the environment and protecting the country against biological threats.

21 Jun 2005

Rosetta Genomics identifies hundreds of novel human microRNAs

In a study published online this week and to be published as a cover story in the July issue of Nature Genetics, Rosetta Genomics' scientists report identification of hundreds of human microRNA genes, including the first report of primate specific microRNAs.

21 Jun 2005

Researchers demonstrate direct transfer of terminally differentiated cell nuclei

With the advent of nuclear-transfer cloning, it is now possible to produce mice from the nuclei of differentiated cells, such as peripheral blood lymphocytes and olfactory sensory neurons.

20 Jun 2005

Baby wallaby bone development may hold key to human development

Melbourne researchers are one step closer to unravelling the secrets of human bone development in a new study involving three-dimensional synchrotron images of baby wallabies.

20 Jun 2005

Melbourne researchers take head lice treatment to the world

A new Victorian biotechnology company, Hatchtech, announced at BIO 2005 that its technology is the first in the world to kill 100% of head lice eggs. International clinical trials are expected to begin within a year and the product may be on market shelves within three years.

19 Jun 2005

New techniques use mitochondrial DNA as an early indicator for certain types of cancer

A pilot study at the National Institute of Standards and Technology (NIST), in support of the National Cancer Institute's Early Detection Research Network (EDRN), has validated the measurement accuracy of new techniques that use mitochondrial DNA as an early indicator for certain types of cancer.

16 Jun 2005

Scientists have tracked down the biological trigger that gives rise to Van Buchem disease

...a hereditary, disfiguring bone disorder that can cause blindness and deafness. The findings provide insight into long-range gene regulation and could lead to new treatments for osteoporosis and other crippling bone disorders.

16 Jun 2005

Research challenges the evolutionary paradigm that continuous alterations occur during the course of genome evolution

Researchers report today that regions of the human genome have been hotspots for acquiring duplicated DNA sequences - but only at specific time-points during evolution.

16 Jun 2005

Jumping genes help detemine uniqueness of individual brains

Scientists at the Salk Institute for Biological Studies may have found one explanation for the puzzling variety in brain organization and function: mobile elements, pieces of DNA that can jump from one place in the genome to another, randomly changing the genetic information in single brain cells.

15 Jun 2005

New research shows that genes exert powerful effect on sexual behavior

New research has shown that the manipulation of a single gene in female fruit flies can make their sexual behavior resemble that of males, in a study that demonstrates the power of individual genes and the profound impact of genetics on complex sexual behavior.

15 Jun 2005

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that enables scientists to mass-produce human papillomavirus (HPV) in the laboratory.

13 Jun 2005

Research accelerates the search for an effective cancer vaccine

By devising a novel way to package the genome of a common human tumor virus - the virus that causes common warts, genital warts and that is implicated in prevalent cancers - scientists have paved the way for making the pathogen far more accessible to biomedical science.

13 Jun 2005

Researchers discover how microRNA are involved in the development of heart muscle

Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle.

12 Jun 2005

Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Researchers led by Dr. Shiv Srivastava from the Center for Prostate Disease Research (CPDR), Uniformed Services University of the Health Sciences (USU), report the groundbreaking discovery of the ETS-Related Gene (ERG) as one of the frequent proto-oncogene overexpressions in prostate cancer cells.

10 Jun 2005

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Using targeted RNA interference, or RNAi libraries, researchers at Harvard Medical School describe the first large-scale classification of kinase and phosphatase gene families on the basis of their role in apoptosis and cell survival. This study appears in the June issue of Nature Cell Biology.

10 Jun 2005

DNA discovery may help explain disorders such as autism

Researchers have made a discovery that may in future help to explain many aspects of human social behavior and disorders such as autism.

10 Jun 2005

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers at Johns Hopkins have uncovered how a majority of the genetic changes in the hepatic-C virus, the most common cause of liver disease, allow it to evade the body's immune system during infection.

10 Jun 2005

Genome News and Research

Study causes big shift in how we think about p53 gene

Technique called phylogenetic footprinting reveals new gene regulation system

Found! - mutant viruses that laid NSW low with gastro

PNNL ScalaBLAST may be used to process complex genomic sequences

Rosetta Genomics identifies hundreds of novel human microRNAs

Researchers demonstrate direct transfer of terminally differentiated cell nuclei

Baby wallaby bone development may hold key to human development

Melbourne researchers take head lice treatment to the world

New techniques use mitochondrial DNA as an early indicator for certain types of cancer

Scientists have tracked down the biological trigger that gives rise to Van Buchem disease

Research challenges the evolutionary paradigm that continuous alterations occur during the course of genome evolution

Jumping genes help detemine uniqueness of individual brains

New research shows that genes exert powerful effect on sexual behavior

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer

Research accelerates the search for an effective cancer vaccine

Researchers discover how microRNA are involved in the development of heart muscle

Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

DNA discovery may help explain disorders such as autism

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

eBook: A guide to RNA sequencing eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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