Glucocorticoid News and Research

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Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).

Breastfeeding changes gene activity that regulates infant's response to stress

It has long been known that there are many physical and mental health benefits of breastfeeding for mothers and babies. But can these benefits be due to genetic changes induced by breastfeeding? New research suggests that connection.

27 Sep 2018

New guidance for treatment of bone loss in hematologic stem cell transplant Recipients

Hematopoietic stem cell transplantation is the treatment of choice for many patients with malignant and non-malignant hematological diseases, such as leukemia and multiple myeloma. The success of recent advances in such transplantation techniques and supportive care measures, has led to greater numbers of long-term HSCT survivors.

20 Sep 2018

Brief yet acute stressors have lasting effects, study finds

Little is known about how brief yet acute stressors – such as war, natural disasters and terror attacks – affect those exposed to them, though human experience suggests they have long-term impacts.

29 Aug 2018

Ferring announces FDA approval of ZOMACTON for injection in four new pediatric indications

Ferring Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has approved ZOMACTON for injection in four additional pediatric indications

20 Jul 2018

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Knopp Biosciences LLC today announced the publication of a report in the journal Blood that a Phase 2 study of dexpramipexole in hypereosinophilic syndromes met its co-primary endpoints.

10 May 2018

New treatment option appears promising for patients with glucocorticoid-induced osteoporosis

About one in every 100 people in the world takes glucocorticoids long term to treat immune-mediated diseases. However, glucocorticoids, such as prednisone, have a side effect -- they induce the bone loss called osteoporosis, causing an estimated yearly bone fracture rate of 5 percent.

27 Apr 2018

Early life stress impacts how the sensory systems develop, review shows

Life needs stimulation. However, overstimulation can cause exhaustion and illness. During specific sensitive periods early in life, stress can even affect later mental health.

16 Apr 2018

LSD1 enzyme regulates skeletal muscle differentiation and metabolic activity

Our bodies convert food into energy for all life activities. These metabolic processes allow the cells that make up our bodies to produce (anabolism) and consume (catabolism) energy molecules from nutrients.

12 Apr 2018

Study shows impact of prenatal stress on offspring stress hormone levels

Vertebrate species, including humans, exposed to stress prenatally tend to have higher stress hormones after birth, according to a new Dartmouth-led study published in Scientific Reports.

11 Apr 2018

Mother's stress during pregnancy changes brain connectivity in-utero

The time babies spend in the womb is far from idle. The brain is changing more rapidly during this time than at any other time in development. It is an active time for the fetus to grow and explore, and of course connect to its mother.

26 Mar 2018

New findings yield insights into factors that contribute to aggressive endometrial tumors

New research from Huntsman Cancer Institute at the University of Utah indicates steroid and hormone receptors are simultaneously active in many endometrial cancer tissues.

13 Mar 2018

New guidelines intend to provide template for optimal, most up-to-date DMD care

Diagnostic and treatment advances are helping patients with Duchenne muscular dystrophy-;one of nine major types of muscular dystrophy that affects males-;live into their 30s and beyond, raising challenges in such areas as education, vocation, levels of independence, personal relationships, emotional health, and intimacy.

13 Mar 2018

Researchers reveal new molecular target to help ease asthma symptoms

Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A -- or VEGFA -- plays a major role in the inflammation and airway obstruction associated with asthma.

7 Mar 2018

Steroid study provides new insights into medicines' side effects

Fresh insights into key hormones found in commonly prescribed medicines have been discovered, providing further understanding of the medicines' side effects.

13 Dec 2017

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.

5 Dec 2017

Johns Hopkins researchers crack key part of mystery surrounding proteins

What makes the body of a person or any other organism work can, for the most part, be summed up in a word: proteins.

28 Nov 2017

Obesity linked to worse patient-reported outcomes in women with lupus

Obesity is independently associated with worse patient-reported outcomes in women with systemic lupus erythematosus, including disease activity, depressive symptoms, pain and fatigue, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

$Opioid and antidepressant use related to increased risk of osteoporotic fractures for RA patients$

Opioid and antidepressant use related to increased risk of osteoporotic fractures for RA patients

Opioids and selective serotonin reuptake inhibitors, a widely used group of antidepressants, are both associated with higher risk of osteoporotic fractures for patients with rheumatoid arthritis, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease

A study published in the journal Nature Neuroscience, from Nature publishing group, describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease.

25 Sep 2017

Research finds new therapeutic strategy to prevent infections in spinal cord injury patients

New research led by The Ohio State University Wexner Medical Center found a potential therapeutic strategy to prevent infections in patients with spinal cord injuries.

22 Sep 2017