Patients with hypertension, diabetes and heart disease more likely to die from COVID-19

As the coronavirus disease (COVID-19) evolves, important information emerges, thanks to studies and analyses undertaken by scientists and health experts. With more data available based on patients in actual healthcare settings, scientists have more information on how the virus affects the body and who are at most risk of the disease.

Now, a team of researchers has found that people with hypertension, diabetes, and heart disease are more likely to die from COVID-19. The study, published in the journal PLOS ONE, is titled, “Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China”.

While it is known that older adults, especially those who are above 60, are at a higher risk of succumbing to the viral infection, the team from Central Hospital of Wuhan, Hubei province, China, confirmed that patients with comorbidities as revealed by computed tomography (CT) scans, were much more likely to die from the disease.

The team linked clinical features identified from CT scans of the lungs of patients with eventual outcomes. They used the CT score based on features they noted on the results, including glass opacity, abnormality on both sides of the lungs, and the widespread distribution of pathology in the lungs.

Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China. Image Credit: Travel Faery / Shutterstock
Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China. Image Credit: Travel Faery / Shutterstock

The study

In the retrospective study, the team recruited 27 patients who fulfilled the clinical criteria for COVID-19, who had developed pneumonia. The patients either recovered from the disease or had died in the hospital. The patients were diagnosed based on the positive results of the throat swab test.

All the patients underwent treatment with intravenous ribavirin 0.5 grams twice daily and oral oseltamivir 75 mg, two times a day. Some patients also had antibiotics, and some received glucocorticoid or immunoglobulin administration.

The patients also had CT scans to visualize their lungs, where the coronavirus wreaks havoc, causing inflammation.

The results of the study show that of the 27 patients, 12 were men and 15 were women. The median age of the patients was 60 years old. Of the 27 patients, 17 recovered and were discharged, while ten died in the hospital.

Comorbidities worsen COVID-19

They found that the median age of those who died was higher than those who recovered. The severity of COVID-19 grows higher as the age of the patient increases. Those who are more than 60 years old are at a higher risk of dying from the infection.

Meanwhile, the study also shows that patients with comorbidities, such as hypertension, diabetes, and cardiac disease, are more likely to die from COVID-19. Eleven patients developed acute respiratory distress syndrome (ARDS), while 10 of them died.

The team also found that there is no difference between males and females in terms of disease severity and death toll.

CT scan score

The team also found that those with higher CT scan scores, or those with severe manifestations based on the results of the CT scan, had a higher chance of dying from the illness. The most common features seen in CT scans include glass opacities, mixed with consolidations, peripheral, or combined peripheral and central distributions, bilateral, and lower lung zones involved.

The team found that the average score of those patients who died was 30, while those who recovered had a CT scan score of 12.

The team notes that the study permits the comparison of radiologic findings with the mortality of patients stricken with COVID-19.

“We hope the simple scoring method, according to CT scans, may help triage patients and screening patients who need more aggressive treatment and close monitoring. However, the efficacy of such an approach to decrease mortality remains to be validated in future studies,” the team wrote in the paper. They added that since the study only involved 27 patients, further and more extensive studies should be done for more accurate results.

Journal reference:

Yuan, M., Yin, W., Tao, Z., Tan, W., and Hu, Y. (2020). Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China. PLOS ONE. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230548

Angela Betsaida B. Laguipo

Written by

Angela Betsaida B. Laguipo

Angela is a nurse by profession and a writer by heart. She graduated with honors (Cum Laude) for her Bachelor of Nursing degree at the University of Baguio, Philippines. She is currently completing her Master's Degree where she specialized in Maternal and Child Nursing and worked as a clinical instructor and educator in the School of Nursing at the University of Baguio.

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Laguipo, Angela. (2020, April 02). Patients with hypertension, diabetes and heart disease more likely to die from COVID-19. News-Medical. Retrieved on June 06, 2020 from https://www.news-medical.net/news/20200402/Patients-with-hypertension-diabetes-and-heart-disease-more-likely-to-die-from-COVID-19.aspx.

  • MLA

    Laguipo, Angela. "Patients with hypertension, diabetes and heart disease more likely to die from COVID-19". News-Medical. 06 June 2020. <https://www.news-medical.net/news/20200402/Patients-with-hypertension-diabetes-and-heart-disease-more-likely-to-die-from-COVID-19.aspx>.

  • Chicago

    Laguipo, Angela. "Patients with hypertension, diabetes and heart disease more likely to die from COVID-19". News-Medical. https://www.news-medical.net/news/20200402/Patients-with-hypertension-diabetes-and-heart-disease-more-likely-to-die-from-COVID-19.aspx. (accessed June 06, 2020).

  • Harvard

    Laguipo, Angela. 2020. Patients with hypertension, diabetes and heart disease more likely to die from COVID-19. News-Medical, viewed 06 June 2020, https://www.news-medical.net/news/20200402/Patients-with-hypertension-diabetes-and-heart-disease-more-likely-to-die-from-COVID-19.aspx.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
You might also like... ×
Kawasaki disease outbreak in children with COVID-19