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How DNA and life experiences leave distinct marks on the human immune system

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and environmental exposures shape the human immune system through distinct DNA methylation mechanisms. Genetic effects concentrate within gene bodies of memory cells, while environmental exposures primarily remodel regulatory regions in naive immune cells.

28 Jan 2026

Lifetime heavy drinking sharply raises colorectal cancer risk, major US study finds

Lifetime alcohol intake, not just recent drinking, is associated with colorectal cancer risk in older adults followed in the PLCO Cancer Screening Trial. Heavy and consistent long-term drinking was linked to higher colorectal cancer risk, while alcohol cessation was associated with lower odds of early, nonadvanced adenomas.

28 Jan 2026

Men still develop heart disease 10 years earlier than women

Historical data indicate that men develop coronary heart disease (CHD) 10 years before women. A recent study in the Journal of the American Heart Association indicates that this sex gap still remains.

28 Jan 2026

Nudges to clinicians and patients increase the rate of influenza vaccination

Patients were 28 percent more likely to get a flu shot when they got a text message reminder and their primary care provider already had an order for the shot waiting, new research from the Perelman School of Medicine showed.

28 Jan 2026

Scientists offer new insight into how common parasite T. gondii causes disease

A University of California, Riverside team of scientists has found that Toxoplasma gondii, a common parasite affecting up to one-third of the global population, is far more complex than previously believed.

27 Jan 2026

Faster hepatitis C treatment with interdisciplinary primary care

Hepatitis C virus treatment is increasingly being offered in primary care because medications now require less frequent monitoring and have fewer adverse effects.

27 Jan 2026

Study identifies genes, smoking, and obesity as pneumonia risk factors

Researchers at the University of Oulu have identified genes that increase susceptibility to pneumonia. Alongside inherited risk factors, smoking and higher body mass were also found to raise the risk of developing the disease.

27 Jan 2026

Analyzing the role of smoking in viral recovery

COVID-19 brought about lasting changes that are still being felt today in the post-pandemic era, with one being the unprecedented side effect known as Long COVID.

27 Jan 2026

Targeted Fab fragments dismantle the allergy trigger

Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such as anaphylaxis, asthma, food allergy, and allergic rhinitis are driven by immunoglobulin E (IgE), an antibody that binds to immune cells, including mast cells and basophils.

27 Jan 2026

Trump policies at odds with emerging understanding of covid’s long-term harm

27 Jan 2026

Blood protein albumin identified as key defense against deadly black fungus

A new international study published in Nature has identified albumin, the most abundant protein in human blood, as a powerful and previously unrecognized defense against mucormycosis, a rare but often fatal fungal infection.

27 Jan 2026

More iron, less damage: why chronic lung infections persist

Research shows that iron-rich conditions boost Pseudomonas aeruginosa growth and biofilm formation, yet reduce virulence, complicating chronic lung infections.

26 Jan 2026

WHO Member States advance negotiations on the Pathogen Access and Benefit‑Sharing system

The World Health Organization (WHO) Member States this week advanced their negotiations on the Pathogen Access and Benefit‑Sharing (PABS) system in a resumed session of the Intergovernmental Working Group (IGWG) on the WHO Pandemic Agreement.

24 Jan 2026

Evidence of African lineage Zika virus circulation in neotropical primates in Southern Brazil

Announcing a new article publication for Zoonoses journal. Mosquito-borne orthoflaviviruses are maintained in cycles involving mosquito and vertebrate hosts.

23 Jan 2026

Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality

Bacterial infections (BIs) are common and severe complications in patients with liver cirrhosis, but global data are limited. Here, we aimed to evaluate the global prevalence, temporal changes, and associated mortality risk of BIs in liver cirrhosis.

23 Jan 2026

Scientists discover a non-classical platelet mechanism linked to severe infections

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor integrin αIIbβ3. This leads to the formation of a stable platelet plug that seals the wound and stops bleeding. When this process becomes dysregulated, however, it can result in vessel-occluding clots - so-called thromboses - which may cause myocardial infarction or stroke.

23 Jan 2026

Study traces deep origins of syphilis to prehistoric Americas

A newly sequenced genome of the bacterium that causes syphilis, Treponema pallidum, highlights the deep antiquity of treponemal diseases in the Americas.

22 Jan 2026

WHO and Novartis extend partnership to eliminate leprosy for another 5 years

Access to treatment for leprosy is essential to global efforts to eliminate leprosy, says the World Health Organization (WHO) ahead of World Leprosy Day, to be observed on 25 January.

22 Jan 2026

Survey shows growing public familiarity with RSV vaccines and antibody injections

Amid a surprisingly severe flu season and a Covid-19 resurgence, those highly contagious respiratory illnesses are drawing the largest share of media coverage and public attention.

21 Jan 2026

Study clarifies role of steroids in treating HSV encephalitis

A major UK clinical trial has shown that adding the corticosteroid dexamethasone to standard antiviral treatment for encephalitis (brain inflammation), caused by herpes simplex virus (HSV) does not improve long-term outcomes overall, although early use may lead to better recovery, and the treatment is safe for patients in whom encephalitis is suspected.

21 Jan 2026

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Disease/Infection News

How DNA and life experiences leave distinct marks on the human immune system

Lifetime heavy drinking sharply raises colorectal cancer risk, major US study finds

Men still develop heart disease 10 years earlier than women

Nudges to clinicians and patients increase the rate of influenza vaccination

Scientists offer new insight into how common parasite T. gondii causes disease

Faster hepatitis C treatment with interdisciplinary primary care

Study identifies genes, smoking, and obesity as pneumonia risk factors

Analyzing the role of smoking in viral recovery

Targeted Fab fragments dismantle the allergy trigger

Trump policies at odds with emerging understanding of covid’s long-term harm

Blood protein albumin identified as key defense against deadly black fungus

More iron, less damage: why chronic lung infections persist

WHO Member States advance negotiations on the Pathogen Access and Benefit‑Sharing system

Evidence of African lineage Zika virus circulation in neotropical primates in Southern Brazil

Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality

Scientists discover a non-classical platelet mechanism linked to severe infections

Study traces deep origins of syphilis to prehistoric Americas

WHO and Novartis extend partnership to eliminate leprosy for another 5 years

Survey shows growing public familiarity with RSV vaccines and antibody injections

Study clarifies role of steroids in treating HSV encephalitis

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