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Machine learning predicts who will decline faster in Alzheimer’s disease using routine clinic data

Researchers developed and validated ElasticNet machine learning models that predict 12-month MMSE and BADL outcomes in Alzheimer’s disease and mild cognitive impairment using routinely collected clinical data. The cognitive model demonstrated external validation in ADNI, showing that individualized progression forecasting is feasible without biomarkers or neuroimaging.

1 Mar 2026

Acoziborole receives positive opinion for single-dose sleeping sickness treatment

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has granted a positive opinion to Acoziborole Winthrop (acoziborole) as a single-dose oral treatment for both early- and advanced-stage gambiense sleeping sickness in adults as well as in adolescents 12 years and older weighing at least 40 kilograms.

27 Feb 2026

New structural insights pave way for hantavirus vaccines

Hantaviruses, transmitted from rodents to people, have a death rate approaching 40%. They're found around the world, and because there are no approved vaccines or treatments, they're among the pathogens of highest concern for future pandemics.

27 Feb 2026

PEX38 protein offers new target against tropical trypanosome diseases

The pathogens that cause tropical diseases rely on an essential protein that is absent from all other organism. This discovery opens the possibility for targeted treatment.

27 Feb 2026

Polystyrene nanoplastics influence Salmonella survival and antibiotic resistance

Plastic products are ubiquitous in our food supply chain, shedding microplastics into every part of the human ecosystem.

27 Feb 2026

WHO updates 2026-2027 flu vaccine composition amidst viral evolution

The World Health Organization (WHO) today announced recommendations for the viral composition of influenza (or "flu") vaccines for the 2026-2027 northern hemisphere influenza season.

27 Feb 2026

Denmark achieves historic elimination of mother-to-child HIV and syphilis transmission

The World Health Organization (WHO) has certified Denmark for the elimination of mother-to-child transmission (EMTCT) of HIV and syphilis, recognizing the country's sustained commitment to ensuring every child is born free of these infections.

27 Feb 2026

Researchers discover critical vulnerability shared by pathogens causing tropical diseases

Researchers working with Professor Ralf Erdmann at Ruhr University Bochum, Germany, have discovered a critical vulnerability shared by the pathogens that cause African sleeping sickness, Chagas disease, and leishmaniasis.

27 Feb 2026

Study highlights systemic forces sustaining tuberculosis transmission

Despite major advances in diagnostics and treatment, tuberculosis (TB) remains the world's deadliest infectious disease.

26 Feb 2026

Scientists uncover key protein essential for malaria parasite survival

An international team of scientists has shed light on the development of the malaria parasite and have identified a unique protein essential for its survival and transmission, which offers a promising new target for antimalaria drugs.

26 Feb 2026

New daily tablet simplifies long-term HIV care

A new, daily oral tablet that combines two current HIV treatment medications, bictegravir and lenacapavir (BIC/LEN), may be able to effectively replace more complicated HIV treatment regimens used by people living with HIV who are long-term survivors, according to the results of a new phase 3 clinical trial published in The Lancet.

26 Feb 2026

Experimental antibiotics disrupt bacterium that causes tuberculosis

Researchers from the University of Sydney and the Centenary Institute have discovered how a promising class of experimental antibiotics disrupts the bacterium that causes tuberculosis (TB), paving the way for urgently needed new treatments.

25 Feb 2026

New single pill regimen simplifies treatment for resistant HIV

A phase 3 clinical trial, led by Professor Chloe Orkin of Queen Mary University of London, has shown that a new, daily oral tablet that combines two current HIV treatment medications – bictegravir and lenacapavir (BIC/LEN) – may simplify treatment significantly for people with HIV who currently take very complex treatments.

25 Feb 2026

RSV and COVID-19 trigger different immune responses in infants

Young infants hospitalized with respiratory syncytial virus (RSV) often become much sicker compared to those infected with SARS-CoV-2, the virus that causes COVID-19.

25 Feb 2026

Prior COVID infection increases kidney disease risk

Approximately one in seven adults in the United States has kidney disease, where the organs responsible for filtering waste and excess water from the blood are damaged, according to the Centers for Disease Control and Prevention.

25 Feb 2026

COVID-19 initially reduced asthma attacks but widened socioeconomic disparities, study finds

A large retrospective study of more than 162,000 asthma patients in the Bronx found that asthma exacerbations dropped sharply after the onset of COVID-19 before rebounding in children but remaining lower in adults. Socioeconomic disparities widened during the pandemic, particularly among Medicaid recipients, certain income groups, and patients with documented unmet social needs, while racial and ethnic gaps persisted without significantly expanding.

25 Feb 2026

Meningococcal B vaccine fails to prevent gonorrhea, trial shows

Contrary to existing evidence from observational studies, the meningococcal B vaccine (4CMenB) has no effect on preventing the acquisition of gonorrhea, according to the results of the world's largest randomized control trial (RCT) into possible efficacy, conducted by Griffith University's Institute for Biomedicine and Glycomics and the Kirby Institute at UNSW Sydney.

25 Feb 2026