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Mature dendritic cell vesicles enhance influenza vaccine effectiveness

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body's immune response, according to a study by researchers in the Institute for Biomedical Sciences at Georgia State University.

2 Jul 2025

As mosquito season peaks, officials brace for new normal of dengue cases

As summer ushers in peak mosquito season, health and vector control officials are bracing for the possibility of another year of historic rates of dengue.

2 Jul 2025

Targeting RAP proteins for next-generation malaria treatments

A University of California, Riverside-led team has made an advance in the basic understanding of Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, that could make novel, highly targeted anti-malarial therapies possible.

1 Jul 2025

Scientists trace leprosy’s roots in South America back 4,000 years

Researchers have recovered and sequenced Mycobacterium lepromatosis genomes from 4,000-year-old human remains in Chile, providing the first molecular evidence of ancient leprosy in the Americas. The findings reveal the deep evolutionary roots and complex spread of Hansen’s disease long before European contact.

1 Jul 2025

HIV treatment linked to risk of early knee osteoarthritis

Acquired immune deficiency syndrome, or AIDS, caused by the human immunodeficiency virus (HIV), weakens the body's immune system and can be life-threatening if left untreated.

1 Jul 2025

Vaccination plays key role in preventing cardiovascular events after infection

Today, a new ESC Clinical Consensus Statement published in the European Heart Journal discusses the key role of vaccination in preventing cardiovascular events following various viral and bacterial infections.

1 Jul 2025

Researchers uncover how bacteria hijack tick cells to survive and spread

Washington State University researchers have discovered how the bacteria that cause anaplasmosis and Lyme disease hijack cellular processes in ticks to ensure their survival and spread to new hosts, including humans.

1 Jul 2025

Macrophage-derived lipocalin 2 drives severe pneumonia in SARS-CoV-2 infection

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying severe pneumonia has remained a major research challenge.

1 Jul 2025

How underreporting masks the real impact of RSV in older populations

Research shows RSV leads to high hospitalization rates in adults, emphasizing the importance of enhanced surveillance and diagnostic measures in healthcare.

1 Jul 2025

Researchers link genetic ancestry to severity of dengue fever

For the first time, the extreme variability in dengue fever has been linked to a biological mechanism, potentially opening doors to new treatments and vaccines for the most common mosquito-borne disease worldwide.

30 Jun 2025

WHO certifies Suriname as malaria free after decades of efforts

Today, Suriname became the first country in the Amazon region to receive malaria-free certification from the World Health Organization (WHO). This historic milestone follows nearly 70 years of commitment by the government and people of Suriname to eliminate the disease across its vast rainforests and diverse communities.

30 Jun 2025

Genetic bottlenecks limit the rise of pandemic cholera strains

A new study by the Genomics and Microbial Evolution Group at the Miguel Hernández University of Elche (UMH) together with the Department of Host-Microbe Interactions at St. Jude Children's Research Hospital in Memphis, USA, sheds light on one of the great enigmas of microbiology: why only certain strains of common bacteria become pandemic pathogens.

30 Jun 2025

GATE complex discovery sheds light on CMV's evasion of immune defenses

New research from the University of Pittsburgh School of Medicine and La Jolla Institute for Immunology, published today in Nature Microbiology, reveals an opportunity for developing a therapy against cytomegalovirus (CMV), the leading infectious cause of birth defects in the United States.

30 Jun 2025

Ancient DNA sheds light on the origins of leprosy in the Americas

Hansen's Disease, more commonly known as leprosy, is a chronic disease that can lead to physical impairment. Today it exists in over 100 countries, and while the infection is treatable, access to treatment varies widely with socioeconomic conditions.

30 Jun 2025

WHO Scientific Advisory Group for the Origins of Novel Pathogens reports on SARS-CoV-2 origins

The WHO Scientific Advisory Group for the Origins of Novel Pathogens (SAGO), a panel of 27 independent, international, multidisciplinary experts, today published its report on the origins of SARS-CoV-2, the virus responsible for the COVID-19 pandemic.

27 Jun 2025

Beetle-inspired tuberculosis testing device offers accurate detection for people with HIV

Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB from traditional tests by eliminating the immune cells relied upon to sound the alarm.

27 Jun 2025

New technology brings antibiotic resistance surveillance to the field

Antibiotics are one of the greatest triumphs in the history of medical science - but these lifesaving tools have a dark side.

26 Jun 2025

New U.S. poll shows strong backing for routine childhood vaccines

In the midst of a multi-state measles outbreak, a new poll by Harvard T.H. Chan School of Public Health and the de Beaumont Foundation finds that most U.S. adults (79%) say parents should be required to have children vaccinated against preventable diseases like measles, mumps, and rubella to attend school.

26 Jun 2025

Updated COVID-19 vaccines found effective against severe illness

A new multi-state study led by the Centers for Disease Control and Prevention's (CDC) VISION Network – including Regenstrief Institute – has provided the most comprehensive assessment to date of the effectiveness of 2023-2024 COVID-19 vaccines among adults in the U.S. during the XBB and JN.1 Omicron subvariant waves.

25 Jun 2025

Gut microbe emerges as a promising tool in the fight against COVID-19

Researchers found that Akkermansia muciniphila boosts lung-specific antiviral immunity against SARS-CoV-2 in mice by modulating the gut–lung axis. This commensal gut bacterium shows promise as a potential biomarker and biotherapeutic candidate for COVID-19 and other respiratory infections.

25 Jun 2025