Disease/Infection News

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Three-drug strategy forces pancreatic tumors into lasting regression

A triple-targeted preclinical therapy combining daraxonrasib, afatinib, and SD36 drove durable pancreatic cancer regression by blocking KRAS/RAS, EGFR/HER2, and STAT3 signaling. The approach prevented treatment resistance across mouse and human tumor-derived models, but remains preclinical and requires more clinically suitable drug combinations before human testing.

2 Jun 2026

Is any level of alcohol safe? Major review reveals where drinking risks rise

This Burden of Proof review found that alcohol consumption is associated with higher risks for several cancers, liver disease, pancreatitis, lower respiratory infections, tuberculosis, and atrial fibrillation. Although low-to-moderate drinking showed modest observational links with lower risks of type 2 diabetes, dementia, and some cardiovascular outcomes, the evidence was weaker and potentially biased.

2 Jun 2026

Gladstone receives NIAID grant to establish the Center for PhAIge Therapy

When a bacterial infection stops responding to antibiotics, doctors have few options to treat it. Phages-viruses that naturally infect and kill bacteria-have long intrigued clinicians as a potential weapon against these infections.

2 Jun 2026

Cross-reactive T cells target measles and dangerous Nipah viruses

T cells are some of the immune system's most important warriors. They can stop tumor growth and even fight off severe infections.

2 Jun 2026

New discovery provides insights into how seasonal influenza viruses infect people

Scientists investigating how influenza viruses replicate within cells "accidentally" discovered that different flu viruses use distinct strategies to infiltrate cells in the first place.

2 Jun 2026

Study shows how HIV leads to chronic pain

Over half of the people carrying HIV experience chronic pain at some point, which is difficult to treat. In a new JNeurosci paper, Hui-Lin Pan, from The University of Texas MD Anderson Cancer Center, and colleagues used mice to explore how HIV leads to chronic pain.

1 Jun 2026

DRC and WHO reaffirm strong partnership to contain Ebola outbreak in Ituri Province

The Government of the Democratic Republic of the Congo (DRC) and the World Health Organization (WHO) reaffirm their strong partnership and shared commitment to protect the health and well-being of the people of Ituri Province and the nation at large, following the joint mission to Bunia led by Dr Samuel Roger Kamba, Minister of Health, Mr. Patrick Muyaya Katembwe, Minister of Communication and Medias, and the visit of WHO Director-General Dr Tedros Adhanom Ghebreyesus.

1 Jun 2026

Why new Alzheimer’s drugs are dividing regulators worldwide

The Lancet World Report examines why regulators in the US, UK, and Europe have reached different decisions on new amyloid-targeting Alzheimer’s drugs despite evidence that they can modestly slow clinical decline. It highlights the unresolved balance among benefits, safety risks, costs, access, and the need for broader, earlier, and more patient-centered treatment strategies.

31 May 2026

Tick protein discovery could help prevent disease transmission

Few creatures inspire as much universal dislike as ticks. Though small, these parasites have an enormous impact on human and animal health. Each year, ticks spread viruses and bacteria that infect people, livestock, wildlife and pets around the world.

29 May 2026

Novel therapeutic agent proposed to combat drug resistant tuberculosis

A research team led by Associate Professor Noriyuki Kurita from the Department of Computer Science and Engineering at Toyohashi University of Technology and by Associate Professor Pornpan Pungpo from Ubon Ratchathani University in Thailand has proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques.

29 May 2026

New approach helps design better antibiotics to fight drug-resistant infections

A new way of designing antibiotics could support the discovery of new treatments for drug-resistant infections.

29 May 2026

WHO prioritizes candidate vaccines and therapeutics for Bundibugyo virus

In response to the current outbreak of Ebola disease caused by Bundibugyo virus occurring in the Democratic Republic of the Congo, with cases also reported in Uganda, WHO convened several of its expert and advisory groups.

29 May 2026

Experimental vaccine triggers broadly neutralizing HIV antibodies in macaques

For years, researchers have been hoping for vaccines that protect people against not just one strain of HIV, but every strain of the quickly mutating virus.

28 May 2026

Gut microbiota may determine severity of life-threatening sepsis infections

Why do some people recover easily from bacterial infections while others rapidly deteriorate into life-threatening sepsis? According to a new study, the answer may lie not only in the invading pathogen itself, but also in the microorganisms already living inside the gut.

28 May 2026

Study reveals inequities in wastewater-based disease outbreak detection systems

Wastewater surveillance was hailed during the COVID-19 pandemic as a more equitable way to track disease.

27 May 2026

Heart health before pandemic influenced severity of COVID-19 infections

Better heart health before the pandemic was linked to a lower risk of severe COVID-19 events, according to research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

27 May 2026

Healthy hearts prior to pandemic reduced severe COVID-19 risk

27 May 2026

Climate change could expand chikungunya into temperate regions worldwide

Chikungunya ('to become contorted' in the Kimakonde language, named after the characteristic joint ache) is classified as one of the neglected tropical diseases by the World Health Organization.

27 May 2026

ICU pneumonia mortality rates remain elevated in developing nations

A scientific review published today in the NEJM Evidence journal, coordinated by the D'Or Institute for Research and Education (IDOR), evaluated outcomes of adults with community-acquired pneumonia (CAP) admitted to intensive care units (ICUs) in middle-income countries.

26 May 2026

New AI tools identify potential drugs for rare Ebola virus

Recent advances in artificial intelligence have enabled Southwest Research Institute (SwRI) to identify nearly two dozen antiviral compounds that could potentially treat a rare species of Ebola virus (Bundibugyo virus) currently affecting the Democratic Republic of Congo.

26 May 2026