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Researchers discover blood gene signatures that can predict COVID-19 severity

A team of scientists from the University of Chicago, NCH Healthcare System and the University of South Florida has identified a specific set of genes associated with a poor prognosis of COVID-19.

26 Nov 2020

Researchers develop synthetic defective SARS-CoV-2 genome that inhibits viral replication

A shorter genome comprising only a part of the SARS-CoV-2's RNA genome competes with the normal virus for growth and can potentially prevent viral replication.

26 Nov 2020

Antihypertensive drugs may reduce COVID-19 mortality in at-risk patients

A new multicenter study that recently appeared on the medRxiv* preprint server in November 2020 has found a lower or equal risk of fatal COVID-19 in hypertensive patients, depending on the type of medication they are on.

26 Nov 2020

Phycobilins found to inhibit SARS-CoV-2 enzymes in vitro

Researchers have released an interesting new study that describes the broad-spectrum of antiviral activity that phycobilins can have. Phycobilins, which are bioactive plant compounds, were found to inhibit two coronavirus enzymes.

26 Nov 2020

Study shows lower light pollution during COVID-19 lockdown in Granada

A novel study reports a favorable change in light pollution during the lockdown in Granada, Spain, from March to May 2020, and has traced it back to several different causes related to COVID-19 lockdown measures.

26 Nov 2020

Early interferon therapy may mitigate COVID-19 severity

A recent review of COVID-19 therapies explores the utility of interferons in the battle against severe COVID-19, and concludes that they deserve further development.

26 Nov 2020

Early use of existing treatment helps save hospitalized COVID-19 patients

The lives of patients hospitalized with COVID-19 are being saved by doctors who are using an existing medical treatment at an earlier stage.

25 Nov 2020

Lungs of COVID-19 patients show good recovery in most cases

Lung tissue of patients who suffered severely from COVID-19 shows good recovery in most cases. This was revealed by a study carried out by the Radboud university medical center that has now been published in Clinical Infectious Diseases.

25 Nov 2020

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

A team of scientists from South Korea and the United States has conducted an interesting study to investigate whether mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect the severity of coronavirus disease 2019 (COVID-19). The study findings reveal that mutations in the viral spike protein and RNA polymerase complex can increase the risk of COVID-19 mortality.

25 Nov 2020

COVID-19 vaccine candidate tested preclinically at UAB poised for Phase 1 clinical study

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer is poised for clinical testing to begin in December.

25 Nov 2020

Half of the population is unaware of the relation between climate change and infectious diseases

Although it is a widely known scientific fact that infectious diseases emerge and re-emerge due to climate change, a study which included the involvement of the UAB published in PlosOne reveals that 48.9% of the population surveyed are not aware of this relation.

25 Nov 2020

Study sheds new light on genetic risk factors that make individuals susceptible to severe COVID-19

Even as tens of thousands of Americans test positive for COVID-19 each day, physicians still aren't sure why some people experience mild to no symptoms while others become critically ill.

25 Nov 2020

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

In a recent cutting-edge study, US researchers unveiled an anti-staphylococcal enterotoxin B monoclonal antibody that can be repurposed to target the cleavage site of the SARS-CoV-2 spike glycoprotein and, in turn, inhibit viral infection. Their findings are currently available on bioRxiv preprint server.

25 Nov 2020

SARS-CoV-2 likely circulating in China as early as mid-October 2019

Researchers in the United States have conducted a modeling study suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – could have been circulating in the Chinese province of Hubei as early as mid-October 2019.

25 Nov 2020

Genomic analysis provides clues about SARS-CoV-2 ancestry and transmission

Researchers in the UK conducting a genomic analysis of severe acute respiratory virus syndrome coronavirus 2 (SARS-CoV-2) and SARS-like coronaviruses in the bat and pangolin have identified strong host-associated divergences that could provide clues about the ancestry and interspecies transmission of SARS-CoV-2.

25 Nov 2020

FDA issues guidance on use of dry heat to support reuse of certain respirators

Today, the U.S. Food and Drug Administration issued guidance on the use of dry heat to help support the single-user reuse of certain particulate filtering facepiece respirators (FFRs), such as N95 respirators, by health care personnel when there is a limited supply of respirators during the COVID-19 public health emergency.

25 Nov 2020

Researchers discover close SARS-CoV-2-relative in animal hosts outside China

In a major new discovery that might deepen our understanding of SARS-CoV-2’s animal origins and its genetic evolution, coronaviruses very closely related to SARS-CoV-2 have been discovered in two horseshoe bats outside of China.

25 Nov 2020

Convalescent plasma treatment ineffective in treating severe COVID-19, study finds

A recent study based at a hospital in Buenos Aires, Argentina, found that convalescent plasma therapy for patients with severe COVID-19, and COVID-19-related pneumonia, was largely ineffective.

25 Nov 2020

Researchers explore prevention measures for SARS-CoV-2 transmission during international travel

Researchers from the Centres for Disease Prevention and Control (CDC) have released findings of their study on the transmission of SARS-CoV-2 via international travel.

25 Nov 2020

Why employers find it so hard to test for COVID

Brandon Hudgins works the main floor at Fleet Feet, a running-shoe store chain, for more than 30 hours a week. He chats with customers, measuring their feet and dashing in and out of the storage area to locate right-sized shoes. Sometimes, clients drag their masks down while speaking. Others refuse to wear masks at all.

25 Nov 2020

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Disease/Infection News

Researchers discover blood gene signatures that can predict COVID-19 severity

Researchers develop synthetic defective SARS-CoV-2 genome that inhibits viral replication

Antihypertensive drugs may reduce COVID-19 mortality in at-risk patients

Phycobilins found to inhibit SARS-CoV-2 enzymes in vitro

Study shows lower light pollution during COVID-19 lockdown in Granada

Early interferon therapy may mitigate COVID-19 severity

Early use of existing treatment helps save hospitalized COVID-19 patients

Lungs of COVID-19 patients show good recovery in most cases

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

COVID-19 vaccine candidate tested preclinically at UAB poised for Phase 1 clinical study

Half of the population is unaware of the relation between climate change and infectious diseases

Study sheds new light on genetic risk factors that make individuals susceptible to severe COVID-19

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

SARS-CoV-2 likely circulating in China as early as mid-October 2019

Genomic analysis provides clues about SARS-CoV-2 ancestry and transmission

FDA issues guidance on use of dry heat to support reuse of certain respirators

Researchers discover close SARS-CoV-2-relative in animal hosts outside China

Convalescent plasma treatment ineffective in treating severe COVID-19, study finds

Researchers explore prevention measures for SARS-CoV-2 transmission during international travel

Why employers find it so hard to test for COVID

The American Lung Association say to wear masks to stop the spread of COVID-19; Here’s why

The Prospects of Semaglutide for Treatment of Type 2 Diabetes Patients

Discovering a new role for a protein that could cause breast cancer to spread to the lungs

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