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Scientists develop monoclonal antibodies combinations that protect animals from Ebola viruses

Scientists from academia, industry, and government have developed a combination of monoclonal antibodies that protected animals from all three Ebola viruses known to cause human disease. Their work is described in two companion studies published online in the journal Cell Host & Microbe.

11 Jan 2019

Clinical evidence firmly confirms the HIV Undetectable = Untransmittable concept

In recent years, an overwhelming body of clinical evidence has firmly established the HIV Undetectable = Untransmittable concept as scientifically sound, say officials from the National Institutes of Health.

11 Jan 2019

Staphylococcus aureus: Study describes development of resistance to antibiotic for the first time

The Staphylococcus aureus bacterium is one of the commonest pathogens and can even cause sepsis. The new antibiotic dalbavancin is very effective against many bacterial pathogens.

10 Jan 2019

Neuropeptide Y may hold key to exacerbating severe influenza

Severe influenza virus infection is characterized by a strong inflammatory response and profuse viral replication in lungs. These viruses, such as the notorious avian flu, have a high rate of death and to date there are no effective treatments.

10 Jan 2019

Viral replication not necessary to cause lethal disease by food-borne pathogen

The replication of a bacterial virus is not necessary to cause lethal disease in a mouse model of a food-borne pathogen called Enterohemorrhagic Escherichia coli, according to a study published January 10 in the open-access journal PLOS Pathogens by Sowmya Balasubramanian, John Leong and Marcia Osburne of Tufts University School of Medicine, and colleagues.

10 Jan 2019

Specific respiratory microbiome may be linked to influenza susceptibility, finds study

Specific respiratory microbiome communities may be linked to influenza susceptibility, according to a study published January 9, 2019 in the open-access journal PLOS ONE by Betsy Foxman from the University of Michigan, USA, and colleagues

10 Jan 2019

Experimental drug can protect against Ebola in a single dose

There is a new medication that in one dose successfully protected nonhuman primates against a lethal infection of all strains of the deadly Ebola virus. The findings are now available in Cell Host & Microbe.

9 Jan 2019

New “drug sponge” could reduce chemotherapy side effects

Researchers have developed a 3D polymer sponge that absorbs excess chemotherapy drugs from the bloodstream following treatment.

9 Jan 2019

Certain psychiatric drugs may increase risk of pneumonia

A review of published studies indicates that use of benzodiazepines and benzodiazepine related drug, which are prescribed to treat various psychiatric diseases, may increase the risk of pneumonia.

9 Jan 2019

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

The Wistar Institute, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc., announce that the FDA has approved the initiation of a first-in-human clinical trial investigating the safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody therapeutic technology for the prevention of Zika virus infection.

9 Jan 2019

New analytic method can precisely detect viral infections using immune responses

Cytomegalovirus is widespread and remains in the body for a lifetime after infection. In healthy individuals, this virus is usually kept in check but can become dangerous when the immune system is weakened or during pregnancy.

8 Jan 2019

High-fat diets shown to increase blood pressure

A new study has added to the evidence that a high-fat diet is unhealthy for both younger males and females. The study also found sex-linked differences in the physiological effects of a HFD.

8 Jan 2019

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Researchers from LSTM and the University of Liverpool have successfully optimized a hit from a whole cell screening of a 10000-compound library to deliver the first novel fully synthetic and rationally designed anti-Wolbachia drug, AWZ1066S, which could potentially be used to treat onchocerciasis and lymphatic filariasis.

8 Jan 2019

The Opal: Pushing the Boundaries of Parkinson’s Disease Research

An interview with Dr. Kristen Sowalsky, discussing a wearable gait sensor and its impact on Parkinson’s disease research.

From APDM Wearable Technologies 8 Jan 2019

USC research could lay foundation for a vaccine against tick-borne virus

Two groundbreaking discoveries by USC researchers could lead to medications and a vaccine to treat or prevent a hemorrhagic fever transmitted by a new tick species before it spreads across the United States.

7 Jan 2019

Faulty immune receptor in HIV patients could be reason why many experience complications

For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues, diabetes and chronic inflammation.

7 Jan 2019

Study confirms increased pneumonia risk with prescription opioids

A study led by researchers at Yale University has shown that taking prescribed opioids increases the risk of pneumonia, irrespective of HIV status.

7 Jan 2019

Alzheimer's pathophysiology shows racial disparities

A study has identified racial disparities between African-Americans and Caucasians in the way in which Alzheimer’s disease arises and develops.

7 Jan 2019

Scientists identify wildlife species that are most likely to host flaviviruses

After collecting data and comparing it with every known mammal and bird species on Earth, scientists from the University of California, Davis, have identified wildlife species that are the most likely to host flaviviruses such as Zika, West Nile, dengue and yellow fever.

6 Jan 2019

New review looks at comprehensive AIDS prevention programs in prisons

In the current issue of Family Medicine and Community Health (Volume 6,Number 4, 2018; DOI: https://doi.org/10.15212/FMCH.2018.0118: , Somayeh Zare, Mehdi Kargar, Jeyran Ostovarfar, Mohammad Hossein Kaveh of the Department of the Health Education and Promotion, School of Health, Shiraz University of Medical Science, Shiraz, Iran discuss how studies show that suitable design of educational programs can affect prisoners' awareness of AIDS.

4 Jan 2019

Disease/Infection News

Scientists develop monoclonal antibodies combinations that protect animals from Ebola viruses

Clinical evidence firmly confirms the HIV Undetectable = Untransmittable concept

Staphylococcus aureus: Study describes development of resistance to antibiotic for the first time

Neuropeptide Y may hold key to exacerbating severe influenza

Viral replication not necessary to cause lethal disease by food-borne pathogen

Specific respiratory microbiome may be linked to influenza susceptibility, finds study

Experimental drug can protect against Ebola in a single dose

New “drug sponge” could reduce chemotherapy side effects

Certain psychiatric drugs may increase risk of pneumonia

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

New analytic method can precisely detect viral infections using immune responses

High-fat diets shown to increase blood pressure

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

The Opal: Pushing the Boundaries of Parkinson’s Disease Research

USC research could lay foundation for a vaccine against tick-borne virus

Faulty immune receptor in HIV patients could be reason why many experience complications

Study confirms increased pneumonia risk with prescription opioids

Alzheimer's pathophysiology shows racial disparities

Scientists identify wildlife species that are most likely to host flaviviruses

New review looks at comprehensive AIDS prevention programs in prisons

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Training Students to use Imaging Techniques: NMR and EPR

High Quality Purification of Proteins Through Liquid Chromatography

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