Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Unlocking the future of dementia: Your telomere length could predict your risk

The recent study in General Psychiatry found that leukocyte telomere length (LTL) is significantly associated with the risk of developing dementia, especially Alzheimer's disease. Using data from over 430,000 individuals, the study suggests that telomere length could serve as a predictive biomarker for brain health and dementia risk.

12 Sep 2023

Can a healthy lifestyle keep depression at bay?

A groundbreaking study reveals that maintaining a healthy lifestyle—including good sleep, social connection, and regular exercise—can significantly reduce the risk of depression, regardless of genetic predisposition. The research emphasizes that lifestyle choices may have a greater impact on depression risk than genetics, offering actionable avenues for prevention.

11 Sep 2023

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Tiziana Life Sciences Ltd. (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies via novel routes of drug delivery, today announced acceptance of a publication, “Nasal Administration of anti-CD3 monoclonal antibody (mAb) ameliorates disease in a mouse model of Alzheimer’s disease”, in the preeminent journal, Proceedings of the National Academy of Sciences (PNAS), that supports foralumab’s mechanism as a potential treatment for Alzheimer’s disease (AD), a difficult-to-treat neuroinflammatory disease.

9 Sep 2023

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

Teen brains with depression show heightened sensitivity to parental criticism

Adolescents with depression show heightened neural activity in response to parental criticism and are less positively impacted by parental praise, according to a study in Psychological Medicine. The research underscores the importance of psycho-education for parents and clinicians to better understand the unique emotional sensitivities of adolescents with depressive disorders.

6 Sep 2023

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Though drug developers have achieved some progress in treating Alzheimer's disease with medicines that reduce amyloid-beta protein, other problems of the disease including inflammation, continue unchecked.

29 Aug 2023

Study examines health impacts of second-hand cigarette smoke exposure

In a recent study, researchers evaluated the effects of chronic second-hand smoke exposure on cognition, behavior, neuropathology, and metabolism.

29 Aug 2023

A review of the neurological imaging techniques in dementia diagnosis

Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.

28 Aug 2023

Time-restricted feeding reverses Alzheimer's symptoms in mice, offers new hope for accessible treatment

Researchers explore the therapeutic potential of circadian-modulating interventions to treat Alzheimer’s disease.

27 Aug 2023

Adolescence stress exposure impacts rodent brain development and behavior

Adolescence stress exposure in rodents can lead to reduced hippocampal cell proliferation, neuroplasticity, and cognitive impairments, as well as increased depressive-like behaviors. These effects may persist into adulthood but with variable impact.

27 Aug 2023

Brain lesions associated with MS memory dysfunction connect to a memory circuit

Between 30 to 50 percent of people living with multiple sclerosis (MS) will experience memory problems but the cause is uncertain.

23 Aug 2023

Max Planck Florida receives NIH funding to investigate the neural circuits underlying Alzheimer's disease

Max Planck Florida will be able to expand their research program to investigate the neural circuits underlying Alzheimer's disease with new support.

22 Aug 2023

The relationship between breast milk feeding and infants’ neurodevelopment via epigenetics

Researchers collated studies on the epigenetic advantages of breast milk feeding and neurodevelopment in infants.

22 Aug 2023

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

The impacts of physical activity on the neuronal formation and prevent age-related cognitive decay.

22 Aug 2023

Melatonin enhances long-term memory by modulating protein phosphorylation

Multiple studies have demonstrated the memory-enhancing effects of melatonin and its derivatives in animal models. It is also known that the formation of both short- and long-term memories require the phosphorylation of certain memory-related proteins.

21 Aug 2023

Hippocampus News and Research

Further Reading

Unlocking the future of dementia: Your telomere length could predict your risk

Can a healthy lifestyle keep depression at bay?

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

Teen brains with depression show heightened sensitivity to parental criticism

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Study examines health impacts of second-hand cigarette smoke exposure

A review of the neurological imaging techniques in dementia diagnosis

Time-restricted feeding reverses Alzheimer's symptoms in mice, offers new hope for accessible treatment

Adolescence stress exposure impacts rodent brain development and behavior

Brain lesions associated with MS memory dysfunction connect to a memory circuit

Max Planck Florida receives NIH funding to investigate the neural circuits underlying Alzheimer's disease

The relationship between breast milk feeding and infants’ neurodevelopment via epigenetics

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

Melatonin enhances long-term memory by modulating protein phosphorylation

The cognitive effects of the MIND diet

Platelets quell the inflammation of an aging brain and body: Study finds

Study provides insight into aging of the brain

Injection of a specific blood factor can replicate the benefits of exercise in the brain

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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