Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Exercise can reverse effects of early-life trauma

Athletes have long known about the natural “high” exercise can induce. Now, for the first time, medical researchers have demonstrated that exercise can reverse the effects in the brain of psychological trauma experienced early in life.

13 Jul 2010

Adeona completes $1 million equity financing and provides update on Zinthionein ZC clinical study

Adeona Pharmaceuticals, Inc., announced today that on July 6, 2010, it completed an equity financing of $1 million with a single institutional investor, Seaside 88, L.P. The financing involved the sale of 1,212,121 registered shares of common stock and no warrants. Enclave Capital served as placement agent and will receive a 7% cash commission and 5-year warrants to acquire 60,606 shares of Adeona at $1.32 per share. The use of proceeds is intended for general corporate purposes.

6 Jul 2010

Research may provide key to understanding interplay between exercise, aging and neurogenesis

Stem cells in the brain remain dormant until called upon to divide and make more neurons. However, little has been known about the molecular guards that keep them quiet.

2 Jul 2010

Imbalance in neuroendocrine system linked to depression in MS patients: Study

Now, in the first such study in living humans, researchers at UCLA suggest a cause, and it's not psychological, but physical: atrophy of a specific region of the hippocampus, a critical part of the brain involved in mood and memory, among other functions.

2 Jul 2010

New research identifies memory and brain scan as best tests for predicting Alzheimer's disease

New research has identified the memory and brain scan tests that appear to predict best whether a person with cognitive problems might develop Alzheimer's disease. The research is published in the June 30, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology.

1 Jul 2010

Sleep enhances ability to remember to do something in future

When it comes to executing items on tomorrow's to-do list, it's best to think it over, then "sleep on it," say psychologists at Washington University in St. Louis.

1 Jul 2010

Research findings open new ways to enhance memory function and treat catastrophic brain diseases

For the first time, scientists have linked a brain compound called kynurenic acid to cognition, possibly opening doors for new ways to enhance memory function and treat catastrophic brain diseases, according to a new study from the University of Maryland School of Medicine. When researchers decreased the levels of kynurenic acid in the brains of mice, their cognition was shown to improve markedly, according to the study, which was published in the July issue of the journal Neuropsychopharmacology.

1 Jul 2010

Researchers use neonatal piglet model to study infant brain development

Events occurring during the development of an infant's brain can leave behind fingerprints. And researchers at the University of Illinois are interested in learning how these fingerprints can predict future behavioral problems such as cognitive deficits, anxiety disorders, depression, and even autism.

29 Jun 2010

ARS study finds link between vitamin D and cognitive function

At a time when consumer interest in health-enhancing foods is high, Agricultural Research Service (ARS)-funded scientists have contributed to a limited but growing body of evidence of a link between vitamin D and cognitive function.

25 Jun 2010

Researchers study how APOE4 becomes a potent risk factor for Alzheimer's disease

A molecule implicated in Alzheimer's disease interferes with brain cells by making them unable to "recycle" the surface receptors that respond to incoming signals, researchers at UT Southwestern Medical Center have found.

15 Jun 2010

New research shows astrocytes play important role in the function of nerve cells

Astrocytes are the most common type of cell in the brain and play an important role in the function of neurons - nerve cells. New research from the University of Gothenburg, Sweden, shows that they are also directly involved in the regulation of signalling between neurons.

15 Jun 2010

Astrocytes involved in regulation of signalling between neurons: Study

14 Jun 2010

Ginkgo extract EGb 761 promotes formation of new nerve cells, cell connections in brain's memory center

US scientists have shown that the Ginkgo extract EGb 761® promotes the formation of new nerve cells and new cell connections in the hippocampus, the brain's memory center. According to Professor Yuan Luo from the University of Maryland, Baltimore, the Ginkgo constituents responsible for these effects are quercetin and bilobalide.

11 Jun 2010

Brain stimulation with ultrasound may enhance cognitive function

The ability to diagnose and treat brain dysfunction without surgery, may rely on a new method of noninvasive brain stimulation using pulsed ultrasound developed by a team of scientists led by William "Jamie" Tyler, a neuroscientist at Arizona State University. The approach, published in the journal Neuron on June 9, shows that pulsed ultrasound not only stimulates action potentials in intact motor cortex in mice but it also "elicits motor responses comparable to those only previously achieved with implanted electrodes and related techniques," says Yusuf Tufail, the lead author from ASU's School of Life Sciences.

10 Jun 2010

Older veterans with PTSD more likely to develop dementia: Report

Older veterans with post-traumatic stress disorder appear more likely to develop dementia over a seven-year period than those without PTSD, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

8 Jun 2010

Adeona completes 50% enrollment in Part 2 CopperProof-2 study of oral zinc cysteine for Alzheimer's Disease

Adeona Pharmaceuticals, Inc. announced the completion of 50% enrollment in Part 2 of its clinical study, A Prospective, Randomized, Double Blind Trial of a Novel Oral Zinc Cysteine Preparation in Alzheimer's Disease (CopperProof-2).

7 Jun 2010

CPAP Therapy increases gray-matter volume in obstructive sleep apnea patients

Obstructive sleep apnea patients had reductions of grey-matter volume at baseline but showed significant grey-matter volume increase after three months of CPAP therapy, according to a research abstract that will be presented Monday, June 7, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

7 Jun 2010

Researchers induce memory of safety in brain of rats

Researchers have found a way to pharmacologically induce a memory of safety in the brain of rats, mimicking the effect of training. The finding suggests possibilities for new treatments for individuals suffering from anxiety disorders.

4 Jun 2010

Research finding suggests possibilities for future treatment of anxiety disorders

Researchers at the University of Puerto Rico, School of Medicine have found a way to pharmacologically induce a memory of safety in the brain of rats. As reported in the June, 4 2010 issue of Science, administering brain-derived neurotrophic factor into the prefrontal cortex prevented rats from expressing fear to a tone that had been previously paired with a shock.

4 Jun 2010

Thymosin beta 4 reduces brain tissue damage, improves brain function in rats: Research paper

RegeneRx Biopharmaceuticals, Inc. announced today that in a preclinical research paper published in the May 2010 issue of the Journal of Neurosurgery, (online ahead of publication), scientists found that the systemic administration of thymosin beta 4, or Tβ4, significantly reduced brain tissue damage and improved brain function in rats with traumatic brain injury, or TBI.

24 May 2010

Hippocampus News and Research

Further Reading

Exercise can reverse effects of early-life trauma

Adeona completes $1 million equity financing and provides update on Zinthionein ZC clinical study

Research may provide key to understanding interplay between exercise, aging and neurogenesis

Imbalance in neuroendocrine system linked to depression in MS patients: Study

New research identifies memory and brain scan as best tests for predicting Alzheimer's disease

Sleep enhances ability to remember to do something in future

Research findings open new ways to enhance memory function and treat catastrophic brain diseases

Researchers use neonatal piglet model to study infant brain development

ARS study finds link between vitamin D and cognitive function

Researchers study how APOE4 becomes a potent risk factor for Alzheimer's disease

New research shows astrocytes play important role in the function of nerve cells

Astrocytes involved in regulation of signalling between neurons: Study

Ginkgo extract EGb 761 promotes formation of new nerve cells, cell connections in brain's memory center

Brain stimulation with ultrasound may enhance cognitive function

Older veterans with PTSD more likely to develop dementia: Report

Adeona completes 50% enrollment in Part 2 CopperProof-2 study of oral zinc cysteine for Alzheimer's Disease

CPAP Therapy increases gray-matter volume in obstructive sleep apnea patients

Researchers induce memory of safety in brain of rats

Research finding suggests possibilities for future treatment of anxiety disorders

Thymosin beta 4 reduces brain tissue damage, improves brain function in rats: Research paper

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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